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Palate Carcinoma

MedGen UID:
107845
•Concept ID:
C0558354
•
Neoplastic Process
Synonyms: Carcinoma of Palate; Carcinoma of the Palate; Palate carcinoma
SNOMED CT: Palate carcinoma (274084007)

Definition

A carcinoma that arises from the hard or soft palate. Representative examples include squamous cell carcinoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma. [from NCI]

Professional guidelines

PubMed

Salvage split course brachytherapy for tonsil and soft palate carcinoma: treatment techniques and results.
Maulard C, Housset M, Delanian S, Ucla L, Rozec C, Chauveinc L, Baillet F
Laryngoscope 1994 Mar;104(3 Pt 1):359-63. doi: 10.1288/00005537-199403000-00019. PMID: 8127194
Oral carcinoma of the upper jaw. Results of radiation treatment.
Shibuya H, Horiuchi J, Suzuki S, Amagasa M, Mashima K
Acta Radiol Oncol 1984;23(5):331-5. doi: 10.3109/02841868409136029. PMID: 6095603

Recent clinical studies

Etiology

Radiation treatment of soft palate squamous cell carcinoma.
Rapp CT, Chera BS, Morris CG, Amdur RJ, Kirwan JM, Mendenhall WM
Head Neck 2020 Mar;42(3):530-538. Epub 2019 Nov 27 doi: 10.1002/hed.26035. PMID: 31773865
Carcinoma of the hard palate treated with radiotherapy: a retrospective review of 31 cases.
Yorozu A, Sykes AJ, Slevin NJ
Oral Oncol 2001 Sep;37(6):493-7. doi: 10.1016/s1368-8375(00)00136-6. PMID: 11435175
Salvage split course brachytherapy for tonsil and soft palate carcinoma: treatment techniques and results.
Maulard C, Housset M, Delanian S, Ucla L, Rozec C, Chauveinc L, Baillet F
Laryngoscope 1994 Mar;104(3 Pt 1):359-63. doi: 10.1288/00005537-199403000-00019. PMID: 8127194
Significance of tumor thickness in soft palate carcinoma.
Baredes S, Leeman DJ, Chen TS, Mohit-Tabatabai MA
Laryngoscope 1993 Apr;103(4 Pt 1):389-93. doi: 10.1002/lary.5541030405. PMID: 8459747
Carcinoma of hard palate in India in relation to reverse smoking of chuttas.
Reddy CR
J Natl Cancer Inst 1974 Sep;53(3):615-9. doi: 10.1093/jnci/53.3.615. PMID: 4412322

Diagnosis

Clear-cell Variant of Mucoepidermoid Carcinoma Presenting as a Palatal Mass in a 10-Year-old Boy.
Han SH, O'Toole TR, Meyer RG, Geiersbach KB, Islam MN, Cheng L, Lai J
Anticancer Res 2023 Feb;43(2):939-942. doi: 10.21873/anticanres.16238. PMID: 36697075
Air gun pellet remaining in the maxillary sinus for 50 years: a relevant risk factor for the patient?
Kühnel TV, Tudor C, Neukam FW, Nkenke E, Stockmann P
Int J Oral Maxillofac Surg 2010 Apr;39(4):407-11. Epub 2009 Dec 3 doi: 10.1016/j.ijom.2009.10.021. PMID: 19962278
Imaging findings of radiation-induced sarcoma of the head and neck.
Makimoto Y, Yamamoto S, Takano H, Motoori K, Ueda T, Kazama T, Kaneoya K, Shimofusa R, Uno T, Ito H, Hanazawa T, Okamoto Y, Hayasaki K
Br J Radiol 2007 Oct;80(958):790-7. Epub 2007 Oct 1 doi: 10.1259/bjr/20938070. PMID: 17908819
Computed tomography of carcinoma of the upper gingiva and hard palate: correlation with the surgical and histopathological findings.
Araki K, Ariji E, Shimizu M, Kanda S, Ozeki S, Shinohara M, Ariji Y
Dentomaxillofac Radiol 1997 May;26(3):177-82. doi: 10.1038/sj.dmfr.4600235. PMID: 9442604
Second head and neck cancers following radiation therapy of T1 and T2 cancers of the oral cavity and oropharynx.
Fijuth J, Mazeron JJ, Le Péchoux C, Piedbois P, Martin M, Haddad E, Calitchi E, Pierquin B, Le Bourgeois JP
Int J Radiat Oncol Biol Phys 1992;24(1):59-64. doi: 10.1016/0360-3016(92)91022-f. PMID: 1512164

Therapy

Prognostic value of p16 expression and alcohol consumption in Japanese patients with oropharyngeal squamous cell carcinoma.
Saito Y, Yoshida M, Ushiku T, Omura G, Ebihara Y, Shimono T, Fukayama M, Yamasoba T, Asakage T
Cancer 2013 Jun 1;119(11):2005-11. Epub 2013 Mar 15 doi: 10.1002/cncr.28015. PMID: 23504914
Second head and neck cancers following radiation therapy of T1 and T2 cancers of the oral cavity and oropharynx.
Fijuth J, Mazeron JJ, Le Péchoux C, Piedbois P, Martin M, Haddad E, Calitchi E, Pierquin B, Le Bourgeois JP
Int J Radiat Oncol Biol Phys 1992;24(1):59-64. doi: 10.1016/0360-3016(92)91022-f. PMID: 1512164
An iridium-192 mold for use in treating carcinoma of the soft palate.
Keys DJ, Marks JE, Sharma SC
Radiology 1979 Dec;133(3 Pt 1):802-3. doi: 10.1148/133.3.802. PMID: 504673

Prognosis

Radiation treatment of soft palate squamous cell carcinoma.
Rapp CT, Chera BS, Morris CG, Amdur RJ, Kirwan JM, Mendenhall WM
Head Neck 2020 Mar;42(3):530-538. Epub 2019 Nov 27 doi: 10.1002/hed.26035. PMID: 31773865
Air gun pellet remaining in the maxillary sinus for 50 years: a relevant risk factor for the patient?
Kühnel TV, Tudor C, Neukam FW, Nkenke E, Stockmann P
Int J Oral Maxillofac Surg 2010 Apr;39(4):407-11. Epub 2009 Dec 3 doi: 10.1016/j.ijom.2009.10.021. PMID: 19962278
Carcinoma of the hard palate treated with radiotherapy: a retrospective review of 31 cases.
Yorozu A, Sykes AJ, Slevin NJ
Oral Oncol 2001 Sep;37(6):493-7. doi: 10.1016/s1368-8375(00)00136-6. PMID: 11435175
Salvage split course brachytherapy for tonsil and soft palate carcinoma: treatment techniques and results.
Maulard C, Housset M, Delanian S, Ucla L, Rozec C, Chauveinc L, Baillet F
Laryngoscope 1994 Mar;104(3 Pt 1):359-63. doi: 10.1288/00005537-199403000-00019. PMID: 8127194
Significance of tumor thickness in soft palate carcinoma.
Baredes S, Leeman DJ, Chen TS, Mohit-Tabatabai MA
Laryngoscope 1993 Apr;103(4 Pt 1):389-93. doi: 10.1002/lary.5541030405. PMID: 8459747

Clinical prediction guides

Imaging findings of radiation-induced sarcoma of the head and neck.
Makimoto Y, Yamamoto S, Takano H, Motoori K, Ueda T, Kazama T, Kaneoya K, Shimofusa R, Uno T, Ito H, Hanazawa T, Okamoto Y, Hayasaki K
Br J Radiol 2007 Oct;80(958):790-7. Epub 2007 Oct 1 doi: 10.1259/bjr/20938070. PMID: 17908819
Carcinoma of the hard palate treated with radiotherapy: a retrospective review of 31 cases.
Yorozu A, Sykes AJ, Slevin NJ
Oral Oncol 2001 Sep;37(6):493-7. doi: 10.1016/s1368-8375(00)00136-6. PMID: 11435175
Salvage split course brachytherapy for tonsil and soft palate carcinoma: treatment techniques and results.
Maulard C, Housset M, Delanian S, Ucla L, Rozec C, Chauveinc L, Baillet F
Laryngoscope 1994 Mar;104(3 Pt 1):359-63. doi: 10.1288/00005537-199403000-00019. PMID: 8127194
Second head and neck cancers following radiation therapy of T1 and T2 cancers of the oral cavity and oropharynx.
Fijuth J, Mazeron JJ, Le Péchoux C, Piedbois P, Martin M, Haddad E, Calitchi E, Pierquin B, Le Bourgeois JP
Int J Radiat Oncol Biol Phys 1992;24(1):59-64. doi: 10.1016/0360-3016(92)91022-f. PMID: 1512164

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