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Malignant Palate Neoplasm

MedGen UID:
57553
•Concept ID:
C0153378
•
Neoplastic Process
Synonyms: CA - Cancer of palate; Cancer of palate; Cancer of Palate; Cancer of the Palate; Malignant Neoplasm of Palate; Malignant neoplasm of roof of mouth; Malignant Neoplasm of the Palate; Malignant Palate Tumor; Malignant tumor of palate; Malignant Tumor of Palate; Malignant tumor of roof of mouth; Malignant Tumor of the Palate; Palate Cancer
SNOMED CT: Malignant tumor of roof of mouth (363390005); Malignant neoplasm of roof of mouth (363390005); Cancer of palate (363390005); CA - Cancer of palate (363390005); Malignant tumor of palate (363390005)

Definition

A primary or metastatic malignant neoplasm that affects the hard palate, soft palate, or uvula. [from NCI]

Professional guidelines

PubMed

Management of NK/T-Cell Lymphoma, Nasal Type.
Allen PB, Lechowicz MJ
J Oncol Pract 2019 Oct;15(10):513-520. doi: 10.1200/JOP.18.00719. PMID: 31600461Free PMC Article
ACR Appropriateness Criteria® ipsilateral radiation for squamous cell carcinoma of the tonsil.
Expert Panel on Radiation Oncology--Head & Neck Cancer:, Yeung AR, Garg MK, Lawson J, McDonald MW, Quon H, Ridge JA, Saba N, Salama JK, Smith RV, Yom SS, Beitler JJ; American College of Radiology
Head Neck 2012 May;34(5):613-6. Epub 2012 Jan 17 doi: 10.1002/hed.21993. PMID: 22250010
Diagnosis and management of primary nasal lymphoma of T-cell or NK-cell origin.
Liang R
Clin Lymphoma 2000 Jun;1(1):33-7; discussion 38. doi: 10.3816/clm.2000.n.002. PMID: 11707809

Recent clinical studies

Etiology

Palate Lymphoma: CT Findings.
Celenk C, Celenk P
AJR Am J Roentgenol 2016 Sep;207(3):628-30. Epub 2016 Jun 24 doi: 10.2214/AJR.16.16360. PMID: 27341038
Reactive hyperplasias,precancerous and malignant lesions of the oral mucosa.
Krahl D, Altenburg A, Zouboulis CC
J Dtsch Dermatol Ges 2008 Mar;6(3):217-32. doi: 10.1111/j.1610-0387.2007.06625.x. PMID: 18315622
Oral cavity and oropharynx tumors.
Stambuk HE, Karimi S, Lee N, Patel SG
Radiol Clin North Am 2007 Jan;45(1):1-20. doi: 10.1016/j.rcl.2006.10.010. PMID: 17157621
Salivary gland neoplasms in Maiduguri, north-eastern Nigeria.
Otoh EC, Johnson NW, Olasoji H, Danfillo IS, Adeleke OA
Oral Dis 2005 Nov;11(6):386-91. doi: 10.1111/j.1601-0825.2005.01137.x. PMID: 16269031
Palatal mass.
Fantasia JE, Damm DD
Gen Dent 2000 Mar-Apr;48(2):140, 203. PMID: 11199572

Diagnosis

Palatal kissing tumors.
Bagnarosa T, Ferri J
J Stomatol Oral Maxillofac Surg 2023 Feb;124(1S):101306. Epub 2022 Oct 12 doi: 10.1016/j.jormas.2022.10.005. PMID: 36241159
Pleomorphic adenoma of hard palate: a case report.
Yousra Z, Saliha C
Pan Afr Med J 2021;38:146. Epub 2021 Feb 9 doi: 10.11604/pamj.2021.38.146.26508. PMID: 33912316Free PMC Article
Palate Lymphoma: CT Findings.
Celenk C, Celenk P
AJR Am J Roentgenol 2016 Sep;207(3):628-30. Epub 2016 Jun 24 doi: 10.2214/AJR.16.16360. PMID: 27341038
Abrikossoff's tumor.
Becelli R, Perugini M, Gasparini G, Cassoni A, Fabiani F
J Craniofac Surg 2001 Jan;12(1):78-81. doi: 10.1097/00001665-200101000-00013. PMID: 11314193
Differential diagnosis of the palatal mass.
Houston GD, Brown FH
Compendium 1993 Oct;14(10):1222-4, 1226, 1228-31; quiz 1232. PMID: 8118828

Therapy

Skeletal and alveolar changes in conventional rapid palatal expansion (RPE) and miniscrew-assisted RPE (MARPE): a prospective randomized clinical trial using low-dose CBCT.
Chun JH, de Castro ACR, Oh S, Kim KH, Choi SH, Nojima LI, Nojima MDCG, Lee KJ
BMC Oral Health 2022 Apr 8;22(1):114. doi: 10.1186/s12903-022-02138-w. PMID: 35395801Free PMC Article
Oncologic causes of oculopalatal tremors: neurophysiology and treatment.
Fiani B, Runnels J, Sarhadi K, Sarno E, Kondilis A
Acta Neurol Belg 2021 Oct;121(5):1111-1116. Epub 2021 Jul 20 doi: 10.1007/s13760-021-01761-8. PMID: 34286476
Oral Kaposi's sarcoma: a review and update.
Fatahzadeh M, Schwartz RA
Int J Dermatol 2013 Jun;52(6):666-72. doi: 10.1111/j.1365-4632.2012.05758.x. PMID: 23679875
Nasopharyngeal carcinoma.
Brennan B
Orphanet J Rare Dis 2006 Jun 26;1:23. doi: 10.1186/1750-1172-1-23. PMID: 16800883Free PMC Article
Pre-irradiation tattooing.
Baluyot ST Jr, Shumrick DA
Arch Otolaryngol 1972 Aug;96(2):151-3. doi: 10.1001/archotol.1972.00770090225011. PMID: 5081919

Prognosis

Polymorphous adenocarcinoma of salivary glands.
Mimica X, Katabi N, McGill MR, Hay A, Zanoni DK, Shah JP, Wong RJ, Cohen MA, Patel SG, Ganly I
Oral Oncol 2019 Aug;95:52-58. Epub 2019 Jun 7 doi: 10.1016/j.oraloncology.2019.06.002. PMID: 31345394Free PMC Article
Oral malignant melanoma--an unusual presentation.
Thomas PS, Babu GS, Anusha RL, Shetty S
Gerodontology 2012 Jun;29(2):e1241-3. Epub 2010 Nov 17 doi: 10.1111/j.1741-2358.2010.00450.x. PMID: 22612841
Oral cavity and oropharynx tumors.
Stambuk HE, Karimi S, Lee N, Patel SG
Radiol Clin North Am 2007 Jan;45(1):1-20. doi: 10.1016/j.rcl.2006.10.010. PMID: 17157621
Head and neck mucosal melanoma.
Mendenhall WM, Amdur RJ, Hinerman RW, Werning JW, Villaret DB, Mendenhall NP
Am J Clin Oncol 2005 Dec;28(6):626-30. doi: 10.1097/01.coc.0000170805.14058.d3. PMID: 16317276
Palatal mass.
Fantasia JE, Damm DD
Gen Dent 2000 Mar-Apr;48(2):140, 203. PMID: 11199572

Clinical prediction guides

Skeletal and alveolar changes in conventional rapid palatal expansion (RPE) and miniscrew-assisted RPE (MARPE): a prospective randomized clinical trial using low-dose CBCT.
Chun JH, de Castro ACR, Oh S, Kim KH, Choi SH, Nojima LI, Nojima MDCG, Lee KJ
BMC Oral Health 2022 Apr 8;22(1):114. doi: 10.1186/s12903-022-02138-w. PMID: 35395801Free PMC Article
Carcinoma Cuniculatum of the Oral Cavity: A Series of 6 Cases and Review of Literature.
Yadav S, Bal M, Rane S, Mittal N, Janu A, Patil A
Head Neck Pathol 2022 Mar;16(1):213-223. Epub 2021 Jun 2 doi: 10.1007/s12105-021-01340-6. PMID: 34076846Free PMC Article
Mucoepidermoid carcinoma: Evaluating the prognostic impact of primary tumor site.
Mimica X, Yuan A, Hay A, Katabi N, Zanoni DK, Valero C, Shah JP, Wong RJ, Cohen MA, Patel SG, Ganly I
Oral Oncol 2021 Dec;123:105602. Epub 2021 Nov 9 doi: 10.1016/j.oraloncology.2021.105602. PMID: 34768210Free PMC Article
Sialolipomas of minor salivary glands: A multi-institutional study and literature review.
Cunha JLS, de Sousa SF, Mota CP, Rocha Silva JV, Cavalcante IL, Marinho EB, Soares CD, de Albuquerque-Júnior RLC, Cavalcante RB, Abrahão AC, Agostini M, Romañach MJ, de Andrade BAB, Vargas PA, de Almeida OP
J Oral Pathol Med 2021 Feb;50(2):210-219. Epub 2021 Jan 12 doi: 10.1111/jop.13124. PMID: 33187016
Hypertrophic Olivary Degeneration: Neurosurgical Perspective and Literature Review.
Onen MR, Moore K, Cikla U, Ucer M, Schmidt B, Field AS, Baskaya MK
World Neurosurg 2018 Apr;112:e763-e771. Epub 2018 Jan 31 doi: 10.1016/j.wneu.2018.01.150. PMID: 29382617

Recent systematic reviews

Long-term efficacy and stability of miniscrew-assisted rapid palatal expansion in mid to late adolescents and adults: a systematic review and meta-analysis.
Zeng W, Yan S, Yi Y, Chen H, Sun T, Zhang Y, Zhang J
BMC Oral Health 2023 Nov 3;23(1):829. doi: 10.1186/s12903-023-03574-y. PMID: 37924088Free PMC Article
Local recurrence and survival after treatment of oral squamous cell carcinoma of the maxilla: A systematic review and meta-analysis.
Slieker FJB, Rombout DAA, de Bree R, Van Cann EM
Oral Surg Oral Med Oral Pathol Oral Radiol 2022 Jun;133(6):626-638. Epub 2021 Oct 13 doi: 10.1016/j.oooo.2021.10.003. PMID: 35165055
Oral Mucosal Melanoma.
Nisi M, Izzetti R, Gennai S, Pucci A, Lenzi C, Graziani F
J Craniofac Surg 2022 May 1;33(3):830-834. Epub 2021 Jul 30 doi: 10.1097/SCS.0000000000008054. PMID: 34334749
How Increased Nodal Metastasis and Recurrence in Cribriform Adenocarcinoma Relate to Polymorphous Adenocarcinoma and Survival: A Systematic Review.
Gates JC, Gargano SM, Cherkas E, Kraus DH, Tuluc M
J Oral Maxillofac Surg 2021 Sep;79(9):1970-1976. Epub 2021 Apr 20 doi: 10.1016/j.joms.2021.03.027. PMID: 34023291
Cervical metastases of oral maxillary squamous cell carcinoma: A systematic review and meta-analysis.
Zhang WB, Peng X
Head Neck 2016 Apr;38 Suppl 1:E2335-42. Epub 2016 Feb 18 doi: 10.1002/hed.24274. PMID: 26890607

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