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Pulmonary opacity

MedGen UID:
1615377
•Concept ID:
C4531104
•
Finding
HPO: HP:0031457

Definition

Opacity refers to any area that preferentially attenuates the x-ray beam and therefore appears more opaque than the surrounding area. It is a nonspecific term that does not indicate the size or pathologic nature of the abnormality. [from HPO]

Professional guidelines

PubMed

Admission chest CT findings and risk assessment for stroke-associated pneumonia.
Arsava EM, Ardali Duzgun S, Durhan G, Cakan M, Akpinar E, Topcuoglu MA
Acta Neurol Belg 2023 Apr;123(2):433-439. Epub 2022 Jul 25 doi: 10.1007/s13760-022-02043-7. PMID: 35879553Free PMC Article
Drug-Related Pneumonitis Induced by Osimertinib as First-Line Treatment for Epidermal Growth Factor Receptor Mutation-Positive Non-Small Cell Lung Cancer: A Real-World Setting.
Sato Y, Sumikawa H, Shibaki R, Morimoto T, Sakata Y, Oya Y, Tamiya M, Suzuki H, Matsumoto H, Yokoi T, Hashimoto K, Kobe H, Hino A, Inaba M, Tsukita Y, Ikeda H, Arai D, Maruyama H, Hara S, Tsumura S, Sakata S, Fujimoto D
Chest 2022 Nov;162(5):1188-1198. Epub 2022 Jun 1 doi: 10.1016/j.chest.2022.05.035. PMID: 35661746
Transient Asymptomatic Pulmonary Opacities Occurring during Osimertinib Treatment.
Noonan SA, Sachs PB, Camidge DR
J Thorac Oncol 2016 Dec;11(12):2253-2258. Epub 2016 Sep 13 doi: 10.1016/j.jtho.2016.08.144. PMID: 27618759Free PMC Article

Recent clinical studies

Etiology

Admission chest CT findings and risk assessment for stroke-associated pneumonia.
Arsava EM, Ardali Duzgun S, Durhan G, Cakan M, Akpinar E, Topcuoglu MA
Acta Neurol Belg 2023 Apr;123(2):433-439. Epub 2022 Jul 25 doi: 10.1007/s13760-022-02043-7. PMID: 35879553Free PMC Article
Drug-Related Pneumonitis Induced by Osimertinib as First-Line Treatment for Epidermal Growth Factor Receptor Mutation-Positive Non-Small Cell Lung Cancer: A Real-World Setting.
Sato Y, Sumikawa H, Shibaki R, Morimoto T, Sakata Y, Oya Y, Tamiya M, Suzuki H, Matsumoto H, Yokoi T, Hashimoto K, Kobe H, Hino A, Inaba M, Tsukita Y, Ikeda H, Arai D, Maruyama H, Hara S, Tsumura S, Sakata S, Fujimoto D
Chest 2022 Nov;162(5):1188-1198. Epub 2022 Jun 1 doi: 10.1016/j.chest.2022.05.035. PMID: 35661746
Associations between CT pulmonary opacity score on admission and clinical characteristics and outcomes in patients with COVID-19.
Luo H, Wang Y, Liu S, Chen R, Chen T, Yang Y, Wang D, Ju S
Intern Emerg Med 2022 Jan;17(1):153-163. Epub 2021 Jun 30 doi: 10.1007/s11739-021-02795-9. PMID: 34191219Free PMC Article
Evaluation of Chest Radiographs of Children with Newly Diagnosed Acute Lymphoblastic Leukemia.
Smith WT, Shiao KT, Varotto E, Zhou Y, Iijima M, Anghelescu DL, Cheng C, Jeha S, Pui CH, Kaste SC, Inaba H
J Pediatr 2020 Aug;223:120-127.e3. doi: 10.1016/j.jpeds.2020.04.003. PMID: 32711740Free PMC Article
Clinical approach to the patient with suspected ventilator-associated pneumonia.
Vidaur L, Sirgo G, Rodríguez AH, Rello J
Respir Care 2005 Jul;50(7):965-74; discussion 974. PMID: 15972116

Diagnosis

Admission chest CT findings and risk assessment for stroke-associated pneumonia.
Arsava EM, Ardali Duzgun S, Durhan G, Cakan M, Akpinar E, Topcuoglu MA
Acta Neurol Belg 2023 Apr;123(2):433-439. Epub 2022 Jul 25 doi: 10.1007/s13760-022-02043-7. PMID: 35879553Free PMC Article
Drug-Related Pneumonitis Induced by Osimertinib as First-Line Treatment for Epidermal Growth Factor Receptor Mutation-Positive Non-Small Cell Lung Cancer: A Real-World Setting.
Sato Y, Sumikawa H, Shibaki R, Morimoto T, Sakata Y, Oya Y, Tamiya M, Suzuki H, Matsumoto H, Yokoi T, Hashimoto K, Kobe H, Hino A, Inaba M, Tsukita Y, Ikeda H, Arai D, Maruyama H, Hara S, Tsumura S, Sakata S, Fujimoto D
Chest 2022 Nov;162(5):1188-1198. Epub 2022 Jun 1 doi: 10.1016/j.chest.2022.05.035. PMID: 35661746
Associations between CT pulmonary opacity score on admission and clinical characteristics and outcomes in patients with COVID-19.
Luo H, Wang Y, Liu S, Chen R, Chen T, Yang Y, Wang D, Ju S
Intern Emerg Med 2022 Jan;17(1):153-163. Epub 2021 Jun 30 doi: 10.1007/s11739-021-02795-9. PMID: 34191219Free PMC Article
Acute pulmonary complications in patients with hematologic malignancies.
Choi MH, Jung JI, Chung WD, Kim YJ, Lee SE, Han DH, Ahn MI, Park SH
Radiographics 2014 Oct;34(6):1755-68. doi: 10.1148/rg.346130107. PMID: 25310429
Clinical approach to the patient with suspected ventilator-associated pneumonia.
Vidaur L, Sirgo G, Rodríguez AH, Rello J
Respir Care 2005 Jul;50(7):965-74; discussion 974. PMID: 15972116

Therapy

Admission chest CT findings and risk assessment for stroke-associated pneumonia.
Arsava EM, Ardali Duzgun S, Durhan G, Cakan M, Akpinar E, Topcuoglu MA
Acta Neurol Belg 2023 Apr;123(2):433-439. Epub 2022 Jul 25 doi: 10.1007/s13760-022-02043-7. PMID: 35879553Free PMC Article
Drug-Related Pneumonitis Induced by Osimertinib as First-Line Treatment for Epidermal Growth Factor Receptor Mutation-Positive Non-Small Cell Lung Cancer: A Real-World Setting.
Sato Y, Sumikawa H, Shibaki R, Morimoto T, Sakata Y, Oya Y, Tamiya M, Suzuki H, Matsumoto H, Yokoi T, Hashimoto K, Kobe H, Hino A, Inaba M, Tsukita Y, Ikeda H, Arai D, Maruyama H, Hara S, Tsumura S, Sakata S, Fujimoto D
Chest 2022 Nov;162(5):1188-1198. Epub 2022 Jun 1 doi: 10.1016/j.chest.2022.05.035. PMID: 35661746
Endobronchial localization of Hodgkin's disease.
Amro L, Jridi S, Sajiai H, Serhane H, Batahar SA
Pan Afr Med J 2017;28:9. Epub 2017 Sep 7 doi: 10.11604/pamj.2017.28.9.11315. PMID: 29138655Free PMC Article
Transient Asymptomatic Pulmonary Opacities Occurring during Osimertinib Treatment.
Noonan SA, Sachs PB, Camidge DR
J Thorac Oncol 2016 Dec;11(12):2253-2258. Epub 2016 Sep 13 doi: 10.1016/j.jtho.2016.08.144. PMID: 27618759Free PMC Article
Clinical approach to the patient with suspected ventilator-associated pneumonia.
Vidaur L, Sirgo G, Rodríguez AH, Rello J
Respir Care 2005 Jul;50(7):965-74; discussion 974. PMID: 15972116

Prognosis

Admission chest CT findings and risk assessment for stroke-associated pneumonia.
Arsava EM, Ardali Duzgun S, Durhan G, Cakan M, Akpinar E, Topcuoglu MA
Acta Neurol Belg 2023 Apr;123(2):433-439. Epub 2022 Jul 25 doi: 10.1007/s13760-022-02043-7. PMID: 35879553Free PMC Article
Evaluation of Follow-Up CT Scans in Patients with Severe Initial Pulmonary Involvement by COVID-19.
Pazooki B, Ahangari A, Mehrabi Nejad MM, Batavani N, Salahshour F
Can Respir J 2022;2022:6972998. Epub 2022 Dec 29 doi: 10.1155/2022/6972998. PMID: 36618585Free PMC Article
Associations between CT pulmonary opacity score on admission and clinical characteristics and outcomes in patients with COVID-19.
Luo H, Wang Y, Liu S, Chen R, Chen T, Yang Y, Wang D, Ju S
Intern Emerg Med 2022 Jan;17(1):153-163. Epub 2021 Jun 30 doi: 10.1007/s11739-021-02795-9. PMID: 34191219Free PMC Article
Dynamic evolution of COVID-19 on chest computed tomography: experience from Jiangsu Province of China.
Wang YC, Luo H, Liu S, Huang S, Zhou Z, Yu Q, Zhang S, Zhao Z, Yu Y, Yang Y, Wang D, Ju S
Eur Radiol 2020 Nov;30(11):6194-6203. Epub 2020 Jun 10 doi: 10.1007/s00330-020-06976-6. PMID: 32524223Free PMC Article
Endobronchial localization of Hodgkin's disease.
Amro L, Jridi S, Sajiai H, Serhane H, Batahar SA
Pan Afr Med J 2017;28:9. Epub 2017 Sep 7 doi: 10.11604/pamj.2017.28.9.11315. PMID: 29138655Free PMC Article

Clinical prediction guides

Imaging features of radiation-induced lung disease and its relationship with clinical and dosimetric factors in breast cancer patients.
Yilmaz U, Koylu M, Savas R, Alanyali S
J Cancer Res Ther 2023 Apr;19(Supplement):S0. doi: 10.4103/jcrt.jcrt_442_21. PMID: 37147965
Admission chest CT findings and risk assessment for stroke-associated pneumonia.
Arsava EM, Ardali Duzgun S, Durhan G, Cakan M, Akpinar E, Topcuoglu MA
Acta Neurol Belg 2023 Apr;123(2):433-439. Epub 2022 Jul 25 doi: 10.1007/s13760-022-02043-7. PMID: 35879553Free PMC Article
Associations between CT pulmonary opacity score on admission and clinical characteristics and outcomes in patients with COVID-19.
Luo H, Wang Y, Liu S, Chen R, Chen T, Yang Y, Wang D, Ju S
Intern Emerg Med 2022 Jan;17(1):153-163. Epub 2021 Jun 30 doi: 10.1007/s11739-021-02795-9. PMID: 34191219Free PMC Article
A nomogram predicting severe COVID-19 based on a large study cohort from China.
Liu S, Luo H, Lei Z, Xu H, Hao T, Chen C, Wang Y, Xie J, Liu L, Ju S, Qiu H, Wang D, Yang Y
Am J Emerg Med 2021 Dec;50:218-223. Epub 2021 Aug 9 doi: 10.1016/j.ajem.2021.08.018. PMID: 34392141Free PMC Article
Age differences in clinical features and outcomes in patients with COVID-19, Jiangsu, China: a retrospective, multicentre cohort study.
Luo H, Liu S, Wang Y, Phillips-Howard PA, Ju S, Yang Y, Wang D
BMJ Open 2020 Oct 5;10(10):e039887. doi: 10.1136/bmjopen-2020-039887. PMID: 33020106Free PMC Article

Recent systematic reviews

Epidemiologic, clinical, and laboratory findings of the COVID-19 in the current pandemic: systematic review and meta-analysis.
Xie Y, Wang Z, Liao H, Marley G, Wu D, Tang W
BMC Infect Dis 2020 Aug 31;20(1):640. doi: 10.1186/s12879-020-05371-2. PMID: 32867706Free PMC Article

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