U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Recurrent Diffuse Large B-Cell Lymphoma

MedGen UID:
163605
•Concept ID:
C0855111
•
Neoplastic Process
Synonym: Relapsed Diffuse Large B-Cell Lymphoma

Definition

The reemergence of diffuse large B-cell lymphoma after a period of remission. [from NCI]

Professional guidelines

PubMed

Follicular lymphoma: 2023 update on diagnosis and management.
Jacobsen E
Am J Hematol 2022 Dec;97(12):1638-1651. Epub 2022 Oct 18 doi: 10.1002/ajh.26737. PMID: 36255040
Treatment strategies for patients with diffuse large B-cell lymphoma.
Poletto S, Novo M, Paruzzo L, Frascione PMM, Vitolo U
Cancer Treat Rev 2022 Nov;110:102443. Epub 2022 Jul 31 doi: 10.1016/j.ctrv.2022.102443. PMID: 35933930
Follicular lymphoma: 2020 update on diagnosis and management.
Freedman A, Jacobsen E
Am J Hematol 2020 Mar;95(3):316-327. Epub 2019 Dec 22 doi: 10.1002/ajh.25696. PMID: 31814159

Recent clinical studies

Etiology

Checking in on Lenalidomide in Diffuse Large B Cell Lymphoma.
Goldfinger M, Xu M, Bertino JR, Cooper DL
Clin Lymphoma Myeloma Leuk 2019 Jun;19(6):e307-e311. Epub 2019 Feb 27 doi: 10.1016/j.clml.2019.02.012. PMID: 30926391
A phase II study of sorafenib (BAY 43-9006) in recurrent diffuse large B cell lymphoma: an eastern cooperative oncology group study (E1404).
Greenwald DR, Li H, Luger SM, Go RS, King D, Patel T, Gascoyne RD, Kolesar J, Kahl BS, Horning S
J Hematol Oncol 2013 Jul 5;6:46. doi: 10.1186/1756-8722-6-46. PMID: 23829878Free PMC Article
Successful treatment of non-Hodgkin lymphoma associated immune thrombocytopenia with involved field radiotherapy.
Berrang T, Holloway C, Hart J, Yee A, Berry B, Kotb R
Hematol Oncol 2013 Dec;31(4):218-20. Epub 2013 Apr 22 doi: 10.1002/hon.2048. PMID: 23606442
Successful treatment with third stem cell transplant from an allogeneic donor for a patient with relapsed diffuse large B-cell lymphoma.
Takasaki H, Ishii Y, Yamamoto W, Tsuchihashi H, Motomura S, Tomita N, Ishigatsubo Y, Sakai R
Exp Clin Transplant 2013 Apr;11(2):199-202. Epub 2013 Feb 20 doi: 10.6002/ect.2012.0105. PMID: 23425447

Diagnosis

Checking in on Lenalidomide in Diffuse Large B Cell Lymphoma.
Goldfinger M, Xu M, Bertino JR, Cooper DL
Clin Lymphoma Myeloma Leuk 2019 Jun;19(6):e307-e311. Epub 2019 Feb 27 doi: 10.1016/j.clml.2019.02.012. PMID: 30926391
Recurrent Diffuse Large B-Cell Lymphoma Presenting with Pancoast Syndrome: A Rare Cause of Radicular Neck Pain in the Emergency Department.
Correia MS, Clark RF
J Emerg Med 2018 Sep;55(3):399-401. Epub 2018 Jul 23 doi: 10.1016/j.jemermed.2018.06.015. PMID: 30049430
Development of taxane-containing chemotherapy of doxorubicin-resistant diffuse large B-cell lymphoma.
Wu L, Wang J, Li Y, Zuo L, Zhang Z, Ouyang J, Fan J, Li H
Anticancer Drugs 2014 Aug;25(7):826-31. doi: 10.1097/CAD.0000000000000067. PMID: 24423982
Early diagnosis of recurrent diffuse large B-cell lymphoma showing intravascular lymphoma by random skin biopsy.
Kasuya A, Hashizume H, Takigawa M
J Dermatol 2011 Jun;38(6):571-4. Epub 2010 Dec 13 doi: 10.1111/j.1346-8138.2010.01127.x. PMID: 21914155
Intravascular lymphomatosis of the skin as a manifestation of recurrent B-cell lymphoma.
Asagoe K, Fujimoto W, Yoshino T, Mannami T, Liu Y, Kanzaki H, Arata J
J Am Acad Dermatol 2003 Feb;48(2 Suppl):S1-4. doi: 10.1067/mjd.2003.112. PMID: 12582370

Therapy

Checking in on Lenalidomide in Diffuse Large B Cell Lymphoma.
Goldfinger M, Xu M, Bertino JR, Cooper DL
Clin Lymphoma Myeloma Leuk 2019 Jun;19(6):e307-e311. Epub 2019 Feb 27 doi: 10.1016/j.clml.2019.02.012. PMID: 30926391
Development of taxane-containing chemotherapy of doxorubicin-resistant diffuse large B-cell lymphoma.
Wu L, Wang J, Li Y, Zuo L, Zhang Z, Ouyang J, Fan J, Li H
Anticancer Drugs 2014 Aug;25(7):826-31. doi: 10.1097/CAD.0000000000000067. PMID: 24423982
Early diagnosis of recurrent diffuse large B-cell lymphoma showing intravascular lymphoma by random skin biopsy.
Kasuya A, Hashizume H, Takigawa M
J Dermatol 2011 Jun;38(6):571-4. Epub 2010 Dec 13 doi: 10.1111/j.1346-8138.2010.01127.x. PMID: 21914155
Response to second-line therapy defines the potential for cure in patients with recurrent diffuse large B-cell lymphoma: implications for the development of novel therapeutic strategies.
Elstrom RL, Martin P, Ostrow K, Barrientos J, Chadburn A, Furman R, Ruan J, Shore T, Schuster M, Cerchietti L, Melnick A, Coleman M, Leonard JP
Clin Lymphoma Myeloma Leuk 2010 Jun;10(3):192-6. doi: 10.3816/CLML.2010.n.030. PMID: 20511164
Phospho-p70S6K/p85S6K and cdc2/cdk1 are novel targets for diffuse large B-cell lymphoma combination therapy.
Zhao MY, Auerbach A, D'Costa AM, Rapoport AP, Burger AM, Sausville EA, Stass SA, Jiang F, Sands AM, Aguilera N, Zhao XF
Clin Cancer Res 2009 Mar 1;15(5):1708-20. Epub 2009 Feb 17 doi: 10.1158/1078-0432.CCR-08-1543. PMID: 19223503

Prognosis

Checking in on Lenalidomide in Diffuse Large B Cell Lymphoma.
Goldfinger M, Xu M, Bertino JR, Cooper DL
Clin Lymphoma Myeloma Leuk 2019 Jun;19(6):e307-e311. Epub 2019 Feb 27 doi: 10.1016/j.clml.2019.02.012. PMID: 30926391
A phase II study of sorafenib (BAY 43-9006) in recurrent diffuse large B cell lymphoma: an eastern cooperative oncology group study (E1404).
Greenwald DR, Li H, Luger SM, Go RS, King D, Patel T, Gascoyne RD, Kolesar J, Kahl BS, Horning S
J Hematol Oncol 2013 Jul 5;6:46. doi: 10.1186/1756-8722-6-46. PMID: 23829878Free PMC Article
Successful treatment with third stem cell transplant from an allogeneic donor for a patient with relapsed diffuse large B-cell lymphoma.
Takasaki H, Ishii Y, Yamamoto W, Tsuchihashi H, Motomura S, Tomita N, Ishigatsubo Y, Sakai R
Exp Clin Transplant 2013 Apr;11(2):199-202. Epub 2013 Feb 20 doi: 10.6002/ect.2012.0105. PMID: 23425447
Response to second-line therapy defines the potential for cure in patients with recurrent diffuse large B-cell lymphoma: implications for the development of novel therapeutic strategies.
Elstrom RL, Martin P, Ostrow K, Barrientos J, Chadburn A, Furman R, Ruan J, Shore T, Schuster M, Cerchietti L, Melnick A, Coleman M, Leonard JP
Clin Lymphoma Myeloma Leuk 2010 Jun;10(3):192-6. doi: 10.3816/CLML.2010.n.030. PMID: 20511164
Intravascular lymphomatosis of the skin as a manifestation of recurrent B-cell lymphoma.
Asagoe K, Fujimoto W, Yoshino T, Mannami T, Liu Y, Kanzaki H, Arata J
J Am Acad Dermatol 2003 Feb;48(2 Suppl):S1-4. doi: 10.1067/mjd.2003.112. PMID: 12582370

Clinical prediction guides

A phase II study of sorafenib (BAY 43-9006) in recurrent diffuse large B cell lymphoma: an eastern cooperative oncology group study (E1404).
Greenwald DR, Li H, Luger SM, Go RS, King D, Patel T, Gascoyne RD, Kolesar J, Kahl BS, Horning S
J Hematol Oncol 2013 Jul 5;6:46. doi: 10.1186/1756-8722-6-46. PMID: 23829878Free PMC Article
Response to second-line therapy defines the potential for cure in patients with recurrent diffuse large B-cell lymphoma: implications for the development of novel therapeutic strategies.
Elstrom RL, Martin P, Ostrow K, Barrientos J, Chadburn A, Furman R, Ruan J, Shore T, Schuster M, Cerchietti L, Melnick A, Coleman M, Leonard JP
Clin Lymphoma Myeloma Leuk 2010 Jun;10(3):192-6. doi: 10.3816/CLML.2010.n.030. PMID: 20511164

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...