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Recurrent Primary Malignant Central Nervous System Neoplasm

MedGen UID:: 1666091
•Concept ID:: C4727424
•: Neoplastic Process

Definition

The reemergence of a primary malignant central nervous system neoplasm after a period of remission. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVRecurrent Primary Malignant Central Nervous System Neoplasm

Disease
- Disorder by Site
  - Disorder of nervous system
    - Disorder of the central nervous system
      - Neoplasm of the central nervous system
        Malignant neoplasm of the central nervous system
        Recurrent Primary Malignant Central Nervous System Neoplasm
        Recurrent Anaplastic (Malignant) Meningioma
        Recurrent Anaplastic Ganglioglioma
        Recurrent Atypical Teratoid/Rhabdoid Tumor
        Recurrent Central Nervous System Lymphoma
        Recurrent Central Nervous System Non-Hodgkin Lymphoma
        Recurrent Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System
        Recurrent Primary Vitreoretinal Non-Hodgkin Lymphoma
        Recurrent Childhood Central Nervous System Embryonal Neoplasm
        Recurrent Childhood Medulloblastoma
        Recurrent Childhood Pineoblastoma
        Recurrent Childhood Supratentorial Embryonal Tumor, Not Otherwise Specified
        Recurrent Malignant Brain Neoplasm
        Recurrent Diffuse Intrinsic Pontine Glioma
        Recurrent Diffuse Midline Glioma, H3 K27M-Mutant
        Recurrent Gliomatosis Cerebri
        Recurrent Childhood Gliomatosis Cerebri
        Recurrent Malignant Choroid Plexus Neoplasm
        Recurrent Medulloblastoma
        Recurrent Medulloblastoma, SHH-Activated
        Recurrent Medulloblastoma, WNT-Activated
        Recurrent Supratentorial Glioblastoma
        Recurrent Malignant Glioma
        Recurrent Glioblastoma
        Recurrent Childhood Glioblastoma
        Recurrent Giant Cell Glioblastoma
        Recurrent Gliosarcoma
        Recurrent Small Cell Glioblastoma
        Recurrent WHO Grade 3 Glioma
        Recurrent Anaplastic Astrocytoma
        Recurrent Anaplastic Ependymoma
        Recurrent Anaplastic Oligoastrocytoma
        Recurrent Anaplastic Oligodendroglioma
        Recurrent Anaplastic Pleomorphic Xanthoastrocytoma
        Recurrent Retinoblastoma

Professional guidelines

PubMed

Primary central nervous system lymphoma.

Ferreri AJM, Calimeri T, Cwynarski K, Dietrich J, Grommes C, Hoang-Xuan K, Hu LS, Illerhaus G, Nayak L, Ponzoni M, Batchelor TT
Nat Rev Dis Primers 2023 Jun 15;9(1):29. doi: 10.1038/s41572-023-00439-0. PMID: 37322012 Free PMC Article

Management of glioblastoma: State of the art and future directions.

Tan AC, Ashley DM, López GY, Malinzak M, Friedman HS, Khasraw M
CA Cancer J Clin 2020 Jul;70(4):299-312. Epub 2020 Jun 1 doi: 10.3322/caac.21613. PMID: 32478924

Current treatment options for meningioma.

Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455

See all (673)

Recent clinical studies

Etiology

Benign Glioma.

Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934

Treatment Options for Recurrent Primary CNS Lymphoma.

Kaulen LD, Baehring JM
Curr Treat Options Oncol 2022 Nov;23(11):1548-1565. Epub 2022 Oct 7 doi: 10.1007/s11864-022-01016-5. PMID: 36205806

Primary Central Nervous System Lymphomas.

Chukwueke U, Grommes C, Nayak L
Hematol Oncol Clin North Am 2022 Feb;36(1):147-159. doi: 10.1016/j.hoc.2021.09.004. PMID: 34801161

Extranodal Diffuse Large B Cell Lymphoma: Molecular Features, Prognosis, and Risk of Central Nervous System Recurrence.

Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605 Free PMC Article

Current treatment options for meningioma.

Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455

See all (3019)

Diagnosis

Primary central nervous system lymphoma.

Evidence-based expert consensus on the management of primary central nervous system lymphoma in China.

Chen T, Liu Y, Wang Y, Chang Q, Wu J, Wang Z, Geng D, Yu JT, Li Y, Li XQ, Chen H, Zhuang D, Li J, Wang B, Jiang T, Lyu L, Song Y, Qiu X, Li W, Lin S, Zhang X, Lu D, Lei J, Chen Y, Mao Y
J Hematol Oncol 2022 Sep 29;15(1):136. doi: 10.1186/s13045-022-01356-7. PMID: 36176002 Free PMC Article

Primary central nervous system lymphoma.

Schaff LR, Grommes C
Blood 2022 Sep 1;140(9):971-979. doi: 10.1182/blood.2020008377. PMID: 34699590 Free PMC Article

Extranodal Diffuse Large B Cell Lymphoma: Molecular Features, Prognosis, and Risk of Central Nervous System Recurrence.

Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605 Free PMC Article

Primary CNS Lymphoma.

Grommes C, DeAngelis LM
J Clin Oncol 2017 Jul 20;35(21):2410-2418. Epub 2017 Jun 22 doi: 10.1200/JCO.2017.72.7602. PMID: 28640701 Free PMC Article

See all (3056)

Therapy

Treatment Options for Recurrent Primary CNS Lymphoma.

Kaulen LD, Baehring JM
Curr Treat Options Oncol 2022 Nov;23(11):1548-1565. Epub 2022 Oct 7 doi: 10.1007/s11864-022-01016-5. PMID: 36205806

Evidence-based expert consensus on the management of primary central nervous system lymphoma in China.

Primary central nervous system lymphoma.

Schaff LR, Grommes C
Blood 2022 Sep 1;140(9):971-979. doi: 10.1182/blood.2020008377. PMID: 34699590 Free PMC Article

Molecular stratifications, biomarker candidates and new therapeutic options in current medulloblastoma treatment approaches.

Menyhárt O, Győrffy B
Cancer Metastasis Rev 2020 Mar;39(1):211-233. doi: 10.1007/s10555-020-09854-1. PMID: 31970590 Free PMC Article

Primary CNS Lymphoma.

Grommes C, DeAngelis LM
J Clin Oncol 2017 Jul 20;35(21):2410-2418. Epub 2017 Jun 22 doi: 10.1200/JCO.2017.72.7602. PMID: 28640701 Free PMC Article

See all (2418)

Prognosis

Primary central nervous system lymphoma.

Schaff LR, Grommes C
Blood 2022 Sep 1;140(9):971-979. doi: 10.1182/blood.2020008377. PMID: 34699590 Free PMC Article

Extranodal Diffuse Large B Cell Lymphoma: Molecular Features, Prognosis, and Risk of Central Nervous System Recurrence.

Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605 Free PMC Article

Current treatment options for meningioma.

Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455

Primary CNS Lymphoma.

Grommes C, DeAngelis LM
J Clin Oncol 2017 Jul 20;35(21):2410-2418. Epub 2017 Jun 22 doi: 10.1200/JCO.2017.72.7602. PMID: 28640701 Free PMC Article

See all (3366)

Clinical prediction guides

Emerging role of artificial intelligence in diagnosis, classification and clinical management of glioma.

Luo J, Pan M, Mo K, Mao Y, Zou D
Semin Cancer Biol 2023 Jun;91:110-123. Epub 2023 Mar 11 doi: 10.1016/j.semcancer.2023.03.006. PMID: 36907387

Central Nervous System Lymphomas.

Grommes C
Continuum (Minneap Minn) 2020 Dec;26(6):1476-1494. doi: 10.1212/CON.0000000000000936. PMID: 33273169

Extranodal Diffuse Large B Cell Lymphoma: Molecular Features, Prognosis, and Risk of Central Nervous System Recurrence.

Ollila TA, Olszewski AJ
Curr Treat Options Oncol 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8. PMID: 29931605 Free PMC Article

Current treatment options for meningioma.

Apra C, Peyre M, Kalamarides M
Expert Rev Neurother 2018 Mar;18(3):241-249. Epub 2018 Jan 22 doi: 10.1080/14737175.2018.1429920. PMID: 29338455

A comprehensive profile of recurrent glioblastoma.

Campos B, Olsen LR, Urup T, Poulsen HS
Oncogene 2016 Nov 10;35(45):5819-5825. Epub 2016 Apr 4 doi: 10.1038/onc.2016.85. PMID: 27041580

See all (1898)

Recent systematic reviews

Glioblastoma Immunotherapy: A Systematic Review of the Present Strategies and Prospects for Advancements.

Agosti E, Zeppieri M, De Maria L, Tedeschi C, Fontanella MM, Panciani PP, Ius T
Int J Mol Sci 2023 Oct 10;24(20) doi: 10.3390/ijms242015037. PMID: 37894718 Free PMC Article

Stereotactic Radiosurgery for Intracranial Primary Melanocytomas.

Dar N, Mantziaris G, Pikis S, Young L, Sheehan J
World Neurosurg 2022 Aug;164:160-166. Epub 2022 May 10 doi: 10.1016/j.wneu.2022.04.136. PMID: 35552031

Primary central nervous system sarcomas in adults: A systematic review.

Haider AS, Palmisciano P, Sagoo NS, Bin Alamer O, El Ahmadieh TY, Pan E, Garzon-Muvdi T
Clin Neurol Neurosurg 2022 Mar;214:107127. Epub 2022 Jan 12 doi: 10.1016/j.clineuro.2022.107127. PMID: 35151057

Treatment options for progression or recurrence of glioblastoma: a network meta-analysis.

McBain C, Lawrie TA, Rogozińska E, Kernohan A, Robinson T, Jefferies S
Cochrane Database Syst Rev 2021 May 4;5(1):CD013579. doi: 10.1002/14651858.CD013579.pub2. PMID: 34559423 Free PMC Article

Re-irradiation for Recurrent Primary Brain Tumors.

Nieder C, Andratschke NH, Grosu AL
Anticancer Res 2016 Oct;36(10):4985-4995. doi: 10.21873/anticanres.11067. PMID: 27798857

See all (105)

MedGen

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Recurrent Primary Malignant Central Nervous System Neoplasm

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Related information

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