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Carcinoma Arising in Bladder Diverticulum

MedGen UID:
1699752
•Concept ID:
C5204991
•
Neoplastic Process

Definition

A carcinoma arising in a bladder diverticulum. Approximately one-third to half of the cases represent non-invasive, low-grade or high-grade urothelial carcinomas. Approximately half of the invasive carcinomas are urothelial. The rest include adenocarcinomas, squamous cell carcinomas, and small cell carcinomas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCarcinoma Arising in Bladder Diverticulum

Recent clinical studies

Etiology

Sensitivity of urine cytology in detecting high-grade urothelial carcinoma in patients with neoplastic urinary bladder diverticula: A major cancer center experience.
Alhamar M, Al-Ahmadie HA, Feratovic R, Lin O
Cancer Cytopathol 2024 Mar;132(3):144-151. Epub 2023 Dec 6 doi: 10.1002/cncy.22782. PMID: 38054371Free PMC Article
Urothelial Carcinoma in Bladder Diverticula: A Multicenter Analysis of Characteristics and Clinical Outcomes.
Voskuilen CS, Seiler R, Rink M, Poyet C, Noon AP, Roghmann F, Necchi A, Aziz A, Lavollé A, Young MJ, Marks P, Saba K, van Rhijn BWG, Fransen van de Putte EE, Ablat J, Black PC, Sosnowski R, Dobruch J, Kumar P, Jallad S, Catto JWF, Xylinas E, Hendricksen K; Young Academic Urologists’ Working Group on Urothelial Carcinoma of the European Association of Urology
Eur Urol Focus 2020 Nov 15;6(6):1226-1232. Epub 2018 Dec 14 doi: 10.1016/j.euf.2018.12.002. PMID: 30559065
Tumour in a giant bladder diverticulum: a case report and review of literature.
Shah B, Rodriguez R, Krasnokutsky S, Shah SM, Ali Khan S
Int Urol Nephrol 1997;29(2):173-9. doi: 10.1007/BF02551338. PMID: 9241544

Diagnosis

Retroperitoneal urothelial carcinoma arising after bladder diverticulectomy: a case report.
Ohtsu A, Arai S, Fujizuka Y, Fukuda R, Hori K, Morimura Y, Kawahara R, Shiraishi T, Ogawa H, Miyazawa Y, Nomura M, Sekine Y, Koike H, Matsui H, Suzuki K
BMC Urol 2023 May 10;23(1):88. doi: 10.1186/s12894-023-01266-x. PMID: 37165362Free PMC Article
Urothelial Carcinoma in Bladder Diverticula: A Multicenter Analysis of Characteristics and Clinical Outcomes.
Voskuilen CS, Seiler R, Rink M, Poyet C, Noon AP, Roghmann F, Necchi A, Aziz A, Lavollé A, Young MJ, Marks P, Saba K, van Rhijn BWG, Fransen van de Putte EE, Ablat J, Black PC, Sosnowski R, Dobruch J, Kumar P, Jallad S, Catto JWF, Xylinas E, Hendricksen K; Young Academic Urologists’ Working Group on Urothelial Carcinoma of the European Association of Urology
Eur Urol Focus 2020 Nov 15;6(6):1226-1232. Epub 2018 Dec 14 doi: 10.1016/j.euf.2018.12.002. PMID: 30559065
Giant Intradiverticular Bladder Tumor.
Md Noh MS, Abdul Aziz AF, Mohd Ghani KA, Lee Kheng Siang C, Yunus R, Mohd Yusof M
Am J Case Rep 2017 Mar 1;18:212-216. doi: 10.12659/ajcr.902101. PMID: 28246375Free PMC Article
Adenocarcinoma Arising from a Bladder Diverticulum.
Fu LY, Adeniran AJ
J Urol 2015 Aug;194(2):527-8. Epub 2015 May 15 doi: 10.1016/j.juro.2015.05.033. PMID: 25986516
Carcinoma arising in urinary bladder diverticula: imaging findings in six patients.
Dondalski M, White EM, Ghahremani GG, Patel SK
AJR Am J Roentgenol 1993 Oct;161(4):817-20. doi: 10.2214/ajr.161.4.8372767. PMID: 8372767

Therapy

Diverticular carcinoma of the urinary bladder: diagnosis and treatment problems. A case report.
Haecker A, Riedasch G, Langbein S, Alken P, Michel MS
Med Princ Pract 2005 Mar-Apr;14(2):121-4. doi: 10.1159/000083925. PMID: 15785107

Prognosis

Retroperitoneal urothelial carcinoma arising after bladder diverticulectomy: a case report.
Ohtsu A, Arai S, Fujizuka Y, Fukuda R, Hori K, Morimura Y, Kawahara R, Shiraishi T, Ogawa H, Miyazawa Y, Nomura M, Sekine Y, Koike H, Matsui H, Suzuki K
BMC Urol 2023 May 10;23(1):88. doi: 10.1186/s12894-023-01266-x. PMID: 37165362Free PMC Article
Diverticular carcinoma of the urinary bladder: diagnosis and treatment problems. A case report.
Haecker A, Riedasch G, Langbein S, Alken P, Michel MS
Med Princ Pract 2005 Mar-Apr;14(2):121-4. doi: 10.1159/000083925. PMID: 15785107
A carcinosarcoma/sarcomatoid carcinoma arising in a urinary bladder diverticulum.
Omeroglu A, Paner GP, Wojcik EM, Siziopikou K
Arch Pathol Lab Med 2002 Jul;126(7):853-5. doi: 10.5858/2002-126-0853-ACSCAI. PMID: 12088458
Tumour in a giant bladder diverticulum: a case report and review of literature.
Shah B, Rodriguez R, Krasnokutsky S, Shah SM, Ali Khan S
Int Urol Nephrol 1997;29(2):173-9. doi: 10.1007/BF02551338. PMID: 9241544
Carcinoma arising in urinary bladder diverticula: imaging findings in six patients.
Dondalski M, White EM, Ghahremani GG, Patel SK
AJR Am J Roentgenol 1993 Oct;161(4):817-20. doi: 10.2214/ajr.161.4.8372767. PMID: 8372767

Clinical prediction guides

Retroperitoneal urothelial carcinoma arising after bladder diverticulectomy: a case report.
Ohtsu A, Arai S, Fujizuka Y, Fukuda R, Hori K, Morimura Y, Kawahara R, Shiraishi T, Ogawa H, Miyazawa Y, Nomura M, Sekine Y, Koike H, Matsui H, Suzuki K
BMC Urol 2023 May 10;23(1):88. doi: 10.1186/s12894-023-01266-x. PMID: 37165362Free PMC Article

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