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Genitourinary System Neoplasm

MedGen UID:
1659531
•Concept ID:
C4744854
•
Neoplastic Process

Definition

A benign or malignant neoplasm that affects the genitourinary system. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGenitourinary System Neoplasm

Professional guidelines

PubMed

Diagnosis and Treatment of AL Amyloidosis.
Palladini G, Milani P
Drugs 2023 Feb;83(3):203-216. Epub 2023 Jan 18 doi: 10.1007/s40265-022-01830-z. PMID: 36652193
Renal cell carcinoma: an overview of the epidemiology, diagnosis, and treatment.
Bahadoram S, Davoodi M, Hassanzadeh S, Bahadoram M, Barahman M, Mafakher L
G Ital Nefrol 2022 Jun 20;39(3) PMID: 35819037
The Diagnosis and Treatment of Prostate Cancer: A Review.
Litwin MS, Tan HJ
JAMA 2017 Jun 27;317(24):2532-2542. doi: 10.1001/jama.2017.7248. PMID: 28655021

Recent clinical studies

Etiology

VI-RADS score system - A primer for urologists.
Nicola R, Pecoraro M, Lucciola S, Dos Reis RB, Narumi Y, Panebianco V, Muglia VF
Int Braz J Urol 2022 Jul-Aug;48(4):609-622. doi: 10.1590/S1677-5538.IBJU.2021.0560. PMID: 35195385Free PMC Article
The Microbiome and Prostate Cancer Risk.
Wheeler KM, Liss MA
Curr Urol Rep 2019 Sep 7;20(10):66. doi: 10.1007/s11934-019-0922-4. PMID: 31493090
Management of genitourinary syndrome of menopause in women with or at high risk for breast cancer: consensus recommendations from The North American Menopause Society and The International Society for the Study of Women's Sexual Health.
Faubion SS, Larkin LC, Stuenkel CA, Bachmann GA, Chism LA, Kagan R, Kaunitz AM, Krychman ML, Parish SJ, Partridge AH, Pinkerton JV, Rowen TS, Shapiro M, Simon JA, Goldfarb SB, Kingsberg SA
Menopause 2018 Jun;25(6):596-608. doi: 10.1097/GME.0000000000001121. PMID: 29762200
ASCENDE-RT: An Analysis of Treatment-Related Morbidity for a Randomized Trial Comparing a Low-Dose-Rate Brachytherapy Boost with a Dose-Escalated External Beam Boost for High- and Intermediate-Risk Prostate Cancer.
Rodda S, Tyldesley S, Morris WJ, Keyes M, Halperin R, Pai H, McKenzie M, Duncan G, Morton G, Hamm J, Murray N
Int J Radiat Oncol Biol Phys 2017 Jun 1;98(2):286-295. Epub 2017 Jan 6 doi: 10.1016/j.ijrobp.2017.01.008. PMID: 28433432
Pediatric urologic oncology.
Grimsby GM, Ritchey ML
Pediatr Clin North Am 2012 Aug;59(4):947-59. Epub 2012 Jun 15 doi: 10.1016/j.pcl.2012.05.018. PMID: 22857841

Diagnosis

Prostate Pathology: What is New in the 2022 WHO Classification of Urinary and Male Genital Tumors?
Surintrspanont J, Zhou M
Pathologica 2022 Feb;115(1):41-56. Epub 2023 Jan 16 doi: 10.32074/1591-951X-822. PMID: 36645399Free PMC Article
Congenital sacrococcygeal rhabdomyosarcoma.
Inuganti RV, Boddapati A, Mathi A, Shaik R
Afr J Paediatr Surg 2022 Oct-Dec;19(4):251-253. doi: 10.4103/ajps.ajps_69_21. PMID: 36018208Free PMC Article
The 2022 World Health Organization Classification of Tumors of the Urinary System and Male Genital Organs-Part B: Prostate and Urinary Tract Tumors.
Netto GJ, Amin MB, Berney DM, Compérat EM, Gill AJ, Hartmann A, Menon S, Raspollini MR, Rubin MA, Srigley JR, Hoon Tan P, Tickoo SK, Tsuzuki T, Turajlic S, Cree I, Moch H
Eur Urol 2022 Nov;82(5):469-482. Epub 2022 Aug 11 doi: 10.1016/j.eururo.2022.07.002. PMID: 35965208
Application of nanotechnology in the diagnosis and treatment of bladder cancer.
Xu Y, Luo C, Wang J, Chen L, Chen J, Chen T, Zeng Q
J Nanobiotechnology 2021 Nov 27;19(1):393. doi: 10.1186/s12951-021-01104-y. PMID: 34838048Free PMC Article
Cowden syndrome and the PTEN hamartoma tumor syndrome: systematic review and revised diagnostic criteria.
Pilarski R, Burt R, Kohlman W, Pho L, Shannon KM, Swisher E
J Natl Cancer Inst 2013 Nov 6;105(21):1607-16. Epub 2013 Oct 17 doi: 10.1093/jnci/djt277. PMID: 24136893

Therapy

Photodynamic Diagnosis-Assisted Transurethral Resection - Lights Out?
Dahm P, Narayan VM
NEJM Evid 2022 Oct;1(10):EVIDe2200194. Epub 2022 Sep 27 doi: 10.1056/EVIDe2200194. PMID: 38319828
Application of nanotechnology in the diagnosis and treatment of bladder cancer.
Xu Y, Luo C, Wang J, Chen L, Chen J, Chen T, Zeng Q
J Nanobiotechnology 2021 Nov 27;19(1):393. doi: 10.1186/s12951-021-01104-y. PMID: 34838048Free PMC Article
Approaches to Non-Muscle-Invasive Bladder Cancer.
Slovacek H, Zhuo J, Taylor JM
Curr Oncol Rep 2021 Jul 16;23(9):105. doi: 10.1007/s11912-021-01091-1. PMID: 34269918
ASCENDE-RT: An Analysis of Treatment-Related Morbidity for a Randomized Trial Comparing a Low-Dose-Rate Brachytherapy Boost with a Dose-Escalated External Beam Boost for High- and Intermediate-Risk Prostate Cancer.
Rodda S, Tyldesley S, Morris WJ, Keyes M, Halperin R, Pai H, McKenzie M, Duncan G, Morton G, Hamm J, Murray N
Int J Radiat Oncol Biol Phys 2017 Jun 1;98(2):286-295. Epub 2017 Jan 6 doi: 10.1016/j.ijrobp.2017.01.008. PMID: 28433432
Treatment of patients with metastatic urothelial cancer "unfit" for Cisplatin-based chemotherapy.
Galsky MD, Hahn NM, Rosenberg J, Sonpavde G, Hutson T, Oh WK, Dreicer R, Vogelzang N, Sternberg CN, Bajorin DF, Bellmunt J
J Clin Oncol 2011 Jun 10;29(17):2432-8. Epub 2011 May 9 doi: 10.1200/JCO.2011.34.8433. PMID: 21555688

Prognosis

Prostate Pathology: What is New in the 2022 WHO Classification of Urinary and Male Genital Tumors?
Surintrspanont J, Zhou M
Pathologica 2022 Feb;115(1):41-56. Epub 2023 Jan 16 doi: 10.32074/1591-951X-822. PMID: 36645399Free PMC Article
Management of Renal Masses and Localized Renal Cancer: Systematic Review and Meta-Analysis.
Pierorazio PM, Johnson MH, Patel HD, Sozio SM, Sharma R, Iyoha E, Bass EB, Allaf ME
J Urol 2016 Oct;196(4):989-99. Epub 2016 May 6 doi: 10.1016/j.juro.2016.04.081. PMID: 27157369Free PMC Article
Pediatric urologic oncology.
Grimsby GM, Ritchey ML
Pediatr Clin North Am 2012 Aug;59(4):947-59. Epub 2012 Jun 15 doi: 10.1016/j.pcl.2012.05.018. PMID: 22857841
Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study.
Hurria A, Togawa K, Mohile SG, Owusu C, Klepin HD, Gross CP, Lichtman SM, Gajra A, Bhatia S, Katheria V, Klapper S, Hansen K, Ramani R, Lachs M, Wong FL, Tew WP
J Clin Oncol 2011 Sep 1;29(25):3457-65. Epub 2011 Aug 1 doi: 10.1200/JCO.2011.34.7625. PMID: 21810685Free PMC Article
Endometrial cancer.
Sorosky JI
Obstet Gynecol 2008 Feb;111(2 Pt 1):436-47. doi: 10.1097/AOG.0b013e318162f690. PMID: 18238985

Clinical prediction guides

Nephrometric scoring system: Recent advances and outlooks.
Xiao Y, Shan ZJ, Yang JF, Len JJ, Yu YH, Yang ML
Urol Oncol 2023 Jan;41(1):15-26. Epub 2022 Jul 28 doi: 10.1016/j.urolonc.2022.06.019. PMID: 35907706
VI-RADS score system - A primer for urologists.
Nicola R, Pecoraro M, Lucciola S, Dos Reis RB, Narumi Y, Panebianco V, Muglia VF
Int Braz J Urol 2022 Jul-Aug;48(4):609-622. doi: 10.1590/S1677-5538.IBJU.2021.0560. PMID: 35195385Free PMC Article
The Microbiome and Prostate Cancer Risk.
Wheeler KM, Liss MA
Curr Urol Rep 2019 Sep 7;20(10):66. doi: 10.1007/s11934-019-0922-4. PMID: 31493090
Syndromes that Link the Endocrine System and Genitourinary Tract.
Özlük Y, Kılıçaslan I
Turk Patoloji Derg 2015;31 Suppl 1:155-71. doi: 10.5146/tjpath.2015.01322. PMID: 26177325
AEG-1/MTDH/LYRIC: clinical significance.
Sarkar D, Fisher PB
Adv Cancer Res 2013;120:39-74. doi: 10.1016/B978-0-12-401676-7.00002-4. PMID: 23889987Free PMC Article

Recent systematic reviews

Molecular Insights in Uterine Leiomyosarcoma: A Systematic Review.
Sparić R, Andjić M, Babović I, Nejković L, Mitrović M, Štulić J, Pupovac M, Tinelli A
Int J Mol Sci 2022 Aug 27;23(17) doi: 10.3390/ijms23179728. PMID: 36077127Free PMC Article
Endometrial hyperplasia as a risk factor of endometrial cancer.
Nees LK, Heublein S, Steinmacher S, Juhasz-Böss I, Brucker S, Tempfer CB, Wallwiener M
Arch Gynecol Obstet 2022 Aug;306(2):407-421. Epub 2022 Jan 10 doi: 10.1007/s00404-021-06380-5. PMID: 35001185Free PMC Article
A Systematic Review of Strategies to Prevent Cisplatin-Induced Nephrotoxicity.
Crona DJ, Faso A, Nishijima TF, McGraw KA, Galsky MD, Milowsky MI
Oncologist 2017 May;22(5):609-619. Epub 2017 Apr 24 doi: 10.1634/theoncologist.2016-0319. PMID: 28438887Free PMC Article
Management of Renal Masses and Localized Renal Cancer: Systematic Review and Meta-Analysis.
Pierorazio PM, Johnson MH, Patel HD, Sozio SM, Sharma R, Iyoha E, Bass EB, Allaf ME
J Urol 2016 Oct;196(4):989-99. Epub 2016 May 6 doi: 10.1016/j.juro.2016.04.081. PMID: 27157369Free PMC Article
Cowden syndrome and the PTEN hamartoma tumor syndrome: systematic review and revised diagnostic criteria.
Pilarski R, Burt R, Kohlman W, Pho L, Shannon KM, Swisher E
J Natl Cancer Inst 2013 Nov 6;105(21):1607-16. Epub 2013 Oct 17 doi: 10.1093/jnci/djt277. PMID: 24136893

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