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Locally Advanced Breast Carcinoma

MedGen UID:
1703295
•Concept ID:
C5205659
•
Neoplastic Process

Definition

A breast carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Professional guidelines

PubMed

Surgical management of locally advanced breast cancer: Recommendations of the Brazilian Society of Surgical Oncology.
da Costa Vieira RA, Andrade WP, Vieira SC, Romano M, Iglesias G, Oliveira AF
J Surg Oncol 2022 Jul;126(1):57-67. doi: 10.1002/jso.26890. PMID: 35689588
Treatment failure following sequential thermoradiotherapy of locally advanced breast carcinoma occurs primarily in poorly vascularized tumors.
Lyng H, Rofstad EK
Oncology 1995 Nov-Dec;52(6):443-7. doi: 10.1159/000227508. PMID: 7478428
Treatment of locally advanced breast carcinoma with high-dose external beam supervoltage radiotherapy.
Brufman G, Weshler Z, Prosnitz LR, Fuks Z
Isr J Med Sci 1981 Sep-Oct;17(9-10):940-5. PMID: 6796541

Recent clinical studies

Etiology

Surgical management of locally advanced breast cancer: Recommendations of the Brazilian Society of Surgical Oncology.
da Costa Vieira RA, Andrade WP, Vieira SC, Romano M, Iglesias G, Oliveira AF
J Surg Oncol 2022 Jul;126(1):57-67. doi: 10.1002/jso.26890. PMID: 35689588
Diffusion-weighted MR imaging of locally advanced breast carcinoma: the optimal time window of predicting the early response to neoadjuvant chemotherapy.
Yuan L, Li JJ, Li CQ, Yan CG, Cheng ZL, Wu YK, Hao P, Lin BQ, Xu YK
Cancer Imaging 2018 Oct 29;18(1):38. doi: 10.1186/s40644-018-0173-5. PMID: 30373679Free PMC Article
Inflammatory breast carcinoma and locally advanced breast carcinoma: characterisation with MR imaging.
Girardi V, Carbognin G, Camera L, Bonetti F, Manfrin E, Pollini G, Pozzi Mucelli R
Radiol Med 2011 Feb;116(1):71-83. Epub 2010 Oct 6 doi: 10.1007/s11547-010-0590-4. PMID: 20927653
Breast conservation following induction chemotherapy for locally advanced carcinoma of the breast (stages IIB and III). A surgical perspective.
Schwartz GF, Lange AK, Topham AK
Surg Oncol Clin N Am 1995 Oct;4(4):657-69. PMID: 8535903
Multimodal therapy in locally advanced breast carcinoma.
Lopez MJ, Andriole DP, Kraybill WG, Khojasteh A
Am J Surg 1990 Dec;160(6):669-74; discussion 674-5. doi: 10.1016/s0002-9610(05)80772-x. PMID: 2252134

Diagnosis

Inflammatory breast carcinoma and locally advanced breast carcinoma: characterisation with MR imaging.
Girardi V, Carbognin G, Camera L, Bonetti F, Manfrin E, Pollini G, Pozzi Mucelli R
Radiol Med 2011 Feb;116(1):71-83. Epub 2010 Oct 6 doi: 10.1007/s11547-010-0590-4. PMID: 20927653
FDG PET, PET/CT, and breast cancer imaging.
Rosen EL, Eubank WB, Mankoff DA
Radiographics 2007 Oct;27 Suppl 1:S215-29. doi: 10.1148/rg.27si075517. PMID: 18180228
Inflammatory breast carcinoma and noninflammatory locally advanced breast carcinoma: distinct clinicopathologic entities?
Anderson WF, Chu KC, Chang S
J Clin Oncol 2003 Jun 15;21(12):2254-9. doi: 10.1200/JCO.2003.07.082. PMID: 12805323
Locally advanced breast carcinoma: accuracy of mammography versus clinical examination in the prediction of residual disease after chemotherapy.
Helvie MA, Joynt LK, Cody RL, Pierce LJ, Adler DD, Merajver SD
Radiology 1996 Feb;198(2):327-32. doi: 10.1148/radiology.198.2.8596826. PMID: 8596826
Multimodal therapy in locally advanced breast carcinoma.
Lopez MJ, Andriole DP, Kraybill WG, Khojasteh A
Am J Surg 1990 Dec;160(6):669-74; discussion 674-5. doi: 10.1016/s0002-9610(05)80772-x. PMID: 2252134

Therapy

Label-free multiphoton imaging to assess neoadjuvant therapy responses in breast carcinoma.
Li L, Han Z, Qiu L, Kang D, Zhan Z, Tu H, Chen J
Int J Biol Sci 2020;16(8):1376-1387. Epub 2020 Feb 21 doi: 10.7150/ijbs.41579. PMID: 32210726Free PMC Article
Locally advanced breast carcinoma: evaluation of mammography in the prediction of residual disease after induction chemotherapy.
Huber S, Wagner M, Zuna I, Medl M, Czembirek H, Delorme S
Anticancer Res 2000 Jan-Feb;20(1B):553-8. PMID: 10769724
Locally advanced breast carcinoma: accuracy of mammography versus clinical examination in the prediction of residual disease after chemotherapy.
Helvie MA, Joynt LK, Cody RL, Pierce LJ, Adler DD, Merajver SD
Radiology 1996 Feb;198(2):327-32. doi: 10.1148/radiology.198.2.8596826. PMID: 8596826
Breast conservation following induction chemotherapy for locally advanced carcinoma of the breast (stages IIB and III). A surgical perspective.
Schwartz GF, Lange AK, Topham AK
Surg Oncol Clin N Am 1995 Oct;4(4):657-69. PMID: 8535903
Multimodal therapy in locally advanced breast carcinoma.
Lopez MJ, Andriole DP, Kraybill WG, Khojasteh A
Am J Surg 1990 Dec;160(6):669-74; discussion 674-5. doi: 10.1016/s0002-9610(05)80772-x. PMID: 2252134

Prognosis

Diffusion-weighted MR imaging of locally advanced breast carcinoma: the optimal time window of predicting the early response to neoadjuvant chemotherapy.
Yuan L, Li JJ, Li CQ, Yan CG, Cheng ZL, Wu YK, Hao P, Lin BQ, Xu YK
Cancer Imaging 2018 Oct 29;18(1):38. doi: 10.1186/s40644-018-0173-5. PMID: 30373679Free PMC Article
Inflammatory breast carcinoma and noninflammatory locally advanced breast carcinoma: distinct clinicopathologic entities?
Anderson WF, Chu KC, Chang S
J Clin Oncol 2003 Jun 15;21(12):2254-9. doi: 10.1200/JCO.2003.07.082. PMID: 12805323
Locally advanced breast carcinoma: accuracy of mammography versus clinical examination in the prediction of residual disease after chemotherapy.
Helvie MA, Joynt LK, Cody RL, Pierce LJ, Adler DD, Merajver SD
Radiology 1996 Feb;198(2):327-32. doi: 10.1148/radiology.198.2.8596826. PMID: 8596826
Multimodal therapy in locally advanced breast carcinoma.
Lopez MJ, Andriole DP, Kraybill WG, Khojasteh A
Am J Surg 1990 Dec;160(6):669-74; discussion 674-5. doi: 10.1016/s0002-9610(05)80772-x. PMID: 2252134
Locally advanced breast carcinoma: results with combined regional therapy.
Toonkel LM, Fix I, Jacobson LH, Bamberg N, Wallach CB
Int J Radiat Oncol Biol Phys 1986 Sep;12(9):1583-7. doi: 10.1016/0360-3016(86)90281-6. PMID: 3759583

Clinical prediction guides

Diffusion-weighted MR imaging of locally advanced breast carcinoma: the optimal time window of predicting the early response to neoadjuvant chemotherapy.
Yuan L, Li JJ, Li CQ, Yan CG, Cheng ZL, Wu YK, Hao P, Lin BQ, Xu YK
Cancer Imaging 2018 Oct 29;18(1):38. doi: 10.1186/s40644-018-0173-5. PMID: 30373679Free PMC Article
Clinical and radiological predictors of nipple-areola complex involvement in breast cancer patients.
D'Alonzo M, Martincich L, Biglia N, Pisacane A, Maggiorotto F, Rosa GD, Montemurro F, Kubatzki F, Sismondi P, Ponzone R
Eur J Cancer 2012 Oct;48(15):2311-8. Epub 2012 May 28 doi: 10.1016/j.ejca.2012.04.017. PMID: 22647686
Inflammatory breast carcinoma and noninflammatory locally advanced breast carcinoma: distinct clinicopathologic entities?
Anderson WF, Chu KC, Chang S
J Clin Oncol 2003 Jun 15;21(12):2254-9. doi: 10.1200/JCO.2003.07.082. PMID: 12805323
Locally advanced breast carcinoma: evaluation of mammography in the prediction of residual disease after induction chemotherapy.
Huber S, Wagner M, Zuna I, Medl M, Czembirek H, Delorme S
Anticancer Res 2000 Jan-Feb;20(1B):553-8. PMID: 10769724
Locally advanced breast carcinoma: accuracy of mammography versus clinical examination in the prediction of residual disease after chemotherapy.
Helvie MA, Joynt LK, Cody RL, Pierce LJ, Adler DD, Merajver SD
Radiology 1996 Feb;198(2):327-32. doi: 10.1148/radiology.198.2.8596826. PMID: 8596826

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