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Intratubular hyaline casts

MedGen UID:
1713070
Concept ID:
C5397650
Finding
Synonym: Intratubular Tamm-Horsfall (uromodulin) casts
 
HPO: HP:0032633

Definition

A type of acellular urinary cast located within the distal tubules of the kidney and that is composed only of Tamm-Horsfall glycoprotein. Correspondingly, these casts have a low refractive index. Hyaline casts may display a spectrum of morphologies, which includes fluffy, compact, convoluted or wrinkled casts. Hyaline casts have a smooth texture and usually have parallel sides with clear margins and blunted ends. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIntratubular hyaline casts

Recent clinical studies

Prognosis

Dvanajscak Z, Cossey LN, Larsen CP
Semin Diagn Pathol 2020 May;37(3):127-134. Epub 2020 Feb 14 doi: 10.1053/j.semdp.2020.02.001. PMID: 32147230

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