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Renal intratubular casts

MedGen UID:
1716393
Concept ID:
C5397641
Finding
Synonym: Tubular casts
 
HPO: HP:0032623

Definition

Urinary casts are formed in the distal convoluted tubule or the collecting duct by solidification of protein in the lumen of the kidney tubules. This term refers to casts located within the tubuli of the kidney. More precisely, casts are defined as a material that completely fills and expands the tubular lumen with simplification of surrounding tubular epithelium. Casts are classified as either nuclear debris/granular brown material, red blood cell, white blood cell, myeloma, or myoglobin cast. [from HPO]

Recent clinical studies

Prognosis

Dvanajscak Z, Cossey LN, Larsen CP
Semin Diagn Pathol 2020 May;37(3):127-134. Epub 2020 Feb 14 doi: 10.1053/j.semdp.2020.02.001. PMID: 32147230

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