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Leukemia Finding

MedGen UID:
1718549
•Concept ID:
C5238555
•
Finding

Definition

A term that refers to clinicopathologic findings related to leukemias. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLeukemia Finding

Professional guidelines

PubMed

Diagnosis and Treatment of Myelodysplastic Syndromes: A Review.
Sekeres MA, Taylor J
JAMA 2022 Sep 6;328(9):872-880. doi: 10.1001/jama.2022.14578. PMID: 36066514
iwCLL guidelines for diagnosis, indications for treatment, response assessment, and supportive management of CLL.
Hallek M, Cheson BD, Catovsky D, Caligaris-Cappio F, Dighiero G, Döhner H, Hillmen P, Keating M, Montserrat E, Chiorazzi N, Stilgenbauer S, Rai KR, Byrd JC, Eichhorst B, O'Brien S, Robak T, Seymour JF, Kipps TJ
Blood 2018 Jun 21;131(25):2745-2760. Epub 2018 Mar 14 doi: 10.1182/blood-2017-09-806398. PMID: 29540348
Acute leukemia in adults: recent developments in diagnosis and treatment.
Devine SM, Larson RA
CA Cancer J Clin 1994 Nov-Dec;44(6):326-52. doi: 10.3322/canjclin.44.6.326. PMID: 7953914

Recent clinical studies

Etiology

Mixed-phenotype acute leukemia: state-of-the-art of the diagnosis, classification and treatment.
Cernan M, Szotkowski T, Pikalova Z
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2017 Sep;161(3):234-241. Epub 2017 Apr 18 doi: 10.5507/bp.2017.013. PMID: 28422191
Leukemia.
Juliusson G, Hough R
Prog Tumor Res 2016;43:87-100. Epub 2016 Sep 5 doi: 10.1159/000447076. PMID: 27595359
Chronic lymphocytic leukaemia.
Scarfò L, Ferreri AJ, Ghia P
Crit Rev Oncol Hematol 2016 Aug;104:169-82. Epub 2016 Jun 16 doi: 10.1016/j.critrevonc.2016.06.003. PMID: 27370174
Multiparameter flow cytometry in the diagnosis and management of acute leukemia.
Peters JM, Ansari MQ
Arch Pathol Lab Med 2011 Jan;135(1):44-54. doi: 10.5858/2010-0387-RAR.1. PMID: 21204710
Classification of acute leukemias.
Brunning RD
Semin Diagn Pathol 2003 Aug;20(3):142-53. doi: 10.1016/s0740-2570(03)00031-5. PMID: 14552428

Diagnosis

How I Diagnose Acute Leukemia of Ambiguous Lineage.
Weinberg OK, Arber DA
Am J Clin Pathol 2022 Jul 1;158(1):27-34. doi: 10.1093/ajcp/aqac070. PMID: 35775438
Neonatal leukaemia.
Roberts I, Fordham NJ, Rao A, Bain BJ
Br J Haematol 2018 Jul;182(2):170-184. Epub 2018 May 28 doi: 10.1111/bjh.15246. PMID: 29806701
Leukemia.
Juliusson G, Hough R
Prog Tumor Res 2016;43:87-100. Epub 2016 Sep 5 doi: 10.1159/000447076. PMID: 27595359
Multiparameter flow cytometry in the diagnosis and management of acute leukemia.
Peters JM, Ansari MQ
Arch Pathol Lab Med 2011 Jan;135(1):44-54. doi: 10.5858/2010-0387-RAR.1. PMID: 21204710
Classification of acute leukemias.
Brunning RD
Semin Diagn Pathol 2003 Aug;20(3):142-53. doi: 10.1016/s0740-2570(03)00031-5. PMID: 14552428

Therapy

Chronic lymphocytic leukemia: 2022 update on diagnostic and therapeutic procedures.
Hallek M, Al-Sawaf O
Am J Hematol 2021 Dec 1;96(12):1679-1705. doi: 10.1002/ajh.26367. PMID: 34625994
How I treat relapsed acute lymphoblastic leukemia in the pediatric population.
Hunger SP, Raetz EA
Blood 2020 Oct 15;136(16):1803-1812. doi: 10.1182/blood.2019004043. PMID: 32589723
Neonatal leukaemia.
Roberts I, Fordham NJ, Rao A, Bain BJ
Br J Haematol 2018 Jul;182(2):170-184. Epub 2018 May 28 doi: 10.1111/bjh.15246. PMID: 29806701
Minimal/measurable residual disease in AML: a consensus document from the European LeukemiaNet MRD Working Party.
Schuurhuis GJ, Heuser M, Freeman S, Béné MC, Buccisano F, Cloos J, Grimwade D, Haferlach T, Hills RK, Hourigan CS, Jorgensen JL, Kern W, Lacombe F, Maurillo L, Preudhomme C, van der Reijden BA, Thiede C, Venditti A, Vyas P, Wood BL, Walter RB, Döhner K, Roboz GJ, Ossenkoppele GJ
Blood 2018 Mar 22;131(12):1275-1291. Epub 2018 Jan 12 doi: 10.1182/blood-2017-09-801498. PMID: 29330221Free PMC Article
Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukaemia: a meta-analysis of individual patient data from randomised controlled trials.
Hills RK, Castaigne S, Appelbaum FR, Delaunay J, Petersdorf S, Othus M, Estey EH, Dombret H, Chevret S, Ifrah N, Cahn JY, Récher C, Chilton L, Moorman AV, Burnett AK
Lancet Oncol 2014 Aug;15(9):986-96. Epub 2014 Jul 6 doi: 10.1016/S1470-2045(14)70281-5. PMID: 25008258Free PMC Article

Prognosis

Leukemia.
Juliusson G, Hough R
Prog Tumor Res 2016;43:87-100. Epub 2016 Sep 5 doi: 10.1159/000447076. PMID: 27595359
Chronic lymphocytic leukaemia.
Scarfò L, Ferreri AJ, Ghia P
Crit Rev Oncol Hematol 2016 Aug;104:169-82. Epub 2016 Jun 16 doi: 10.1016/j.critrevonc.2016.06.003. PMID: 27370174
Leukemia: an overview for primary care.
Davis AS, Viera AJ, Mead MD
Am Fam Physician 2014 May 1;89(9):731-8. PMID: 24784336
Multiparameter flow cytometry in the diagnosis and management of acute leukemia.
Peters JM, Ansari MQ
Arch Pathol Lab Med 2011 Jan;135(1):44-54. doi: 10.5858/2010-0387-RAR.1. PMID: 21204710
Acute myeloid leukemia: epidemiology and etiology.
Deschler B, Lübbert M
Cancer 2006 Nov 1;107(9):2099-107. doi: 10.1002/cncr.22233. PMID: 17019734

Clinical prediction guides

The MDS genomics-prognosis symbiosis.
Nazha A
Hematology Am Soc Hematol Educ Program 2018 Nov 30;2018(1):270-276. doi: 10.1182/asheducation-2018.1.270. PMID: 30504321Free PMC Article
Neonatal leukaemia.
Roberts I, Fordham NJ, Rao A, Bain BJ
Br J Haematol 2018 Jul;182(2):170-184. Epub 2018 May 28 doi: 10.1111/bjh.15246. PMID: 29806701
A 17-gene stemness score for rapid determination of risk in acute leukaemia.
Ng SW, Mitchell A, Kennedy JA, Chen WC, McLeod J, Ibrahimova N, Arruda A, Popescu A, Gupta V, Schimmer AD, Schuh AC, Yee KW, Bullinger L, Herold T, Görlich D, Büchner T, Hiddemann W, Berdel WE, Wörmann B, Cheok M, Preudhomme C, Dombret H, Metzeler K, Buske C, Löwenberg B, Valk PJ, Zandstra PW, Minden MD, Dick JE, Wang JC
Nature 2016 Dec 15;540(7633):433-437. Epub 2016 Dec 7 doi: 10.1038/nature20598. PMID: 27926740
Chronic lymphocytic leukaemia.
Scarfò L, Ferreri AJ, Ghia P
Crit Rev Oncol Hematol 2016 Aug;104:169-82. Epub 2016 Jun 16 doi: 10.1016/j.critrevonc.2016.06.003. PMID: 27370174
Molecular classification of cancer: class discovery and class prediction by gene expression monitoring.
Golub TR, Slonim DK, Tamayo P, Huard C, Gaasenbeek M, Mesirov JP, Coller H, Loh ML, Downing JR, Caligiuri MA, Bloomfield CD, Lander ES
Science 1999 Oct 15;286(5439):531-7. doi: 10.1126/science.286.5439.531. PMID: 10521349

Recent systematic reviews

Ultra-processed food consumption and cancer risk: A systematic review and meta-analysis.
Isaksen IM, Dankel SN
Clin Nutr 2023 Jun;42(6):919-928. Epub 2023 Mar 30 doi: 10.1016/j.clnu.2023.03.018. PMID: 37087831
Association of Measurable Residual Disease With Survival Outcomes in Patients With Acute Myeloid Leukemia: A Systematic Review and Meta-analysis.
Short NJ, Zhou S, Fu C, Berry DA, Walter RB, Freeman SD, Hourigan CS, Huang X, Nogueras Gonzalez G, Hwang H, Qi X, Kantarjian H, Ravandi F
JAMA Oncol 2020 Dec 1;6(12):1890-1899. doi: 10.1001/jamaoncol.2020.4600. PMID: 33030517Free PMC Article
Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America Clinical Practice Guideline Update.
Taplitz RA, Kennedy EB, Bow EJ, Crews J, Gleason C, Hawley DK, Langston AA, Nastoupil LJ, Rajotte M, Rolston K, Strasfeld L, Flowers CR
J Clin Oncol 2018 May 10;36(14):1443-1453. Epub 2018 Feb 20 doi: 10.1200/JCO.2017.77.6211. PMID: 29461916
Splenic irradiation for splenomegaly: A systematic review.
Zaorsky NG, Williams GR, Barta SK, Esnaola NF, Kropf PL, Hayes SB, Meyer JE
Cancer Treat Rev 2017 Feb;53:47-52. Epub 2016 Dec 22 doi: 10.1016/j.ctrv.2016.11.016. PMID: 28063304Free PMC Article
Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies.
Renehan AG, Tyson M, Egger M, Heller RF, Zwahlen M
Lancet 2008 Feb 16;371(9612):569-78. doi: 10.1016/S0140-6736(08)60269-X. PMID: 18280327

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