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Benign Maxillofacial Neoplasm

MedGen UID:: 1766349
•Concept ID:: C5420433
•: Neoplastic Process

Definition

A neoplasm that arises from a maxillofacial bone and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVBenign Maxillofacial Neoplasm

Disease
- Neoplasm
  - Neoplasm by Special Category
    - Benign neoplasm
      - Benign Head and Neck Neoplasm
        Benign Skull Neoplasm
        Benign Maxillofacial Neoplasm
        Maxillofacial Chondroblastoma
        Maxillofacial Chondroma
        Maxillofacial Chondromyxoid Fibroma
        Maxillofacial Desmoplastic Fibroma
        Maxillofacial Osteoblastoma
        Maxillofacial Osteoid Osteoma
        Maxillofacial Osteoma

Professional guidelines

PubMed

How effective is 5-Fluorouracil as an adjuvant in the management of odontogenic keratocyst? A systematic review and meta-analysis.

Singh AK, Khanal N, Chaulagain R, Bhujel N, Singh RP
Br J Oral Maxillofac Surg 2022 Jul;60(6):746-754. Epub 2022 Feb 17 doi: 10.1016/j.bjoms.2022.02.001. PMID: 35314081

Pediatric Aggressive Benign Mandibular Tumors: Clinical Features and Management.

Koraitim M, Medra AM, Salloum AM, Shehata EA
J Craniofac Surg 2022 May 1;33(3):e265-e267. Epub 2021 Aug 13 doi: 10.1097/SCS.0000000000008085. PMID: 34387270

Ameloblastoma: current etiopathological concepts and management.

Effiom OA, Ogundana OM, Akinshipo AO, Akintoye SO
Oral Dis 2018 Apr;24(3):307-316. Epub 2017 Mar 9 doi: 10.1111/odi.12646. PMID: 28142213

See all (67)

Recent clinical studies

Etiology

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Odontogenic and Maxillofacial Bone Tumours.

Vered M, Wright JM
Head Neck Pathol 2022 Mar;16(1):63-75. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01404-7. PMID: 35312978 Free PMC Article

Black and Brown Oro-facial Mucocutaneous Neoplasms.

Natarajan E
Head Neck Pathol 2019 Mar;13(1):56-70. Epub 2019 Jan 29 doi: 10.1007/s12105-019-01008-2. PMID: 30693458 Free PMC Article

Matter of margins.

Gualdi G, Monari P, Crotti S, Damiani G, Facchetti F, Calzavara-Pinton P, Fantini F
J Eur Acad Dermatol Venereol 2015 Feb;29(2):255-261. Epub 2014 Jul 30 doi: 10.1111/jdv.12504. PMID: 25074680

Odontogenic tumors.

Chrysomali E, Leventis M, Titsinides S, Kyriakopoulos V, Sklavounou A
J Craniofac Surg 2013 Sep;24(5):1521-5. doi: 10.1097/SCS.0b013e3182997aaf. PMID: 24036718

Maxillary ameloblastoma.

Bozza F, Marcelli VA, Pistilli R, Govoni FA, Marsico C
Minerva Stomatol 2006 Apr;55(4):215-22. PMID: 16618996

See all (796)

Diagnosis

The World Health Organization Classification of Odontogenic Lesions: A Summary of the Changes of the 2022 (5th) Edition.

Soluk-Tekkesin M, Wright JM
Turk Patoloji Derg 2022;38(2):168-184. doi: 10.5146/tjpath.2022.01573. PMID: 35578902 Free PMC Article

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Odontogenic and Maxillofacial Bone Tumours.

Vered M, Wright JM
Head Neck Pathol 2022 Mar;16(1):63-75. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01404-7. PMID: 35312978 Free PMC Article

Benign and Malignant Lesions of Jaw.

Ramana Reddy BV, Kiran Kumar K, Rajendra Santosh AB
Dent Clin North Am 2020 Jan;64(1):39-61. Epub 2019 Oct 21 doi: 10.1016/j.cden.2019.08.005. PMID: 31735233

Ameloblastoma: current etiopathological concepts and management.

Effiom OA, Ogundana OM, Akinshipo AO, Akintoye SO
Oral Dis 2018 Apr;24(3):307-316. Epub 2017 Mar 9 doi: 10.1111/odi.12646. PMID: 28142213

Ameloblastic Carcinoma.

Gunaratne DA, Coleman HG, Lim L, Morgan GJ
Am J Case Rep 2015 Jul 1;16:415-9. doi: 10.12659/AJCR.893918. PMID: 26126621 Free PMC Article

See all (1225)

Therapy

Effectiveness of different treatments for odontogenic keratocyst: a network meta-analysis.

Al-Moraissi EA, Kaur A, Gomez RS, Ellis E 3rd
Int J Oral Maxillofac Surg 2023 Jan;52(1):32-43. Epub 2022 Sep 21 doi: 10.1016/j.ijom.2022.09.004. PMID: 36150944

Effectiveness of molecular-targeted chemotherapy in ameloblastomas: A systematic review.

Yoithapprabhunath TR, Srichinthu KK, Gupta D, Singh D, Pasupuleti S, Nirmal RM
Indian J Dent Res 2022 Jul-Sep;33(3):323-331. doi: 10.4103/ijdr.ijdr_456_22. PMID: 36656197

How effective is 5-Fluorouracil as an adjuvant in the management of odontogenic keratocyst? A systematic review and meta-analysis.

Singh AK, Khanal N, Chaulagain R, Bhujel N, Singh RP
Br J Oral Maxillofac Surg 2022 Jul;60(6):746-754. Epub 2022 Feb 17 doi: 10.1016/j.bjoms.2022.02.001. PMID: 35314081

Osteonecrosis of the Jaw and Antiresorptive Agents in Benign and Malignant Diseases: A Critical Review Organized by the ECTS.

Anastasilakis AD, Pepe J, Napoli N, Palermo A, Magopoulos C, Khan AA, Zillikens MC, Body JJ
J Clin Endocrinol Metab 2022 Apr 19;107(5):1441-1460. doi: 10.1210/clinem/dgab888. PMID: 34922381 Free PMC Article

Recent advances in the histopathological assessment of salivary disease.

Chegini S, Brennan PA, Rahimi S, Shakib K
J Oral Pathol Med 2020 Aug;49(7):601-605. Epub 2020 Mar 2 doi: 10.1111/jop.13002. PMID: 32027401

See all (139)

Prognosis

Effectiveness of different treatments for odontogenic keratocyst: a network meta-analysis.

Al-Moraissi EA, Kaur A, Gomez RS, Ellis E 3rd
Int J Oral Maxillofac Surg 2023 Jan;52(1):32-43. Epub 2022 Sep 21 doi: 10.1016/j.ijom.2022.09.004. PMID: 36150944

Ameloblastoma: A succinct review of the classification, genetic understanding and novel molecular targeted therapies.

Shi HA, Ng CWB, Kwa CT, Sim QXC
Surgeon 2021 Aug;19(4):238-243. Epub 2020 Jul 22 doi: 10.1016/j.surge.2020.06.009. PMID: 32712102

An Update on Tumors of the Lacrimal Gland.

Andreasen S, Esmaeli B, Holstein SL, Mikkelsen LH, Rasmussen PK, Heegaard S
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):159-172. doi: 10.22608/APO.201707. PMID: 28399336

Immunohistochemical biomarkers in ameloblastomas.

do Canto AM, Rozatto JR, Schussel JL, de Freitas RR, Hasséus B, Braz-Silva PH
Acta Odontol Scand 2016 Nov;74(8):585-590. Epub 2016 Aug 30 doi: 10.1080/00016357.2016.1224918. PMID: 27571891

Matter of margins.

Gualdi G, Monari P, Crotti S, Damiani G, Facchetti F, Calzavara-Pinton P, Fantini F
J Eur Acad Dermatol Venereol 2015 Feb;29(2):255-261. Epub 2014 Jul 30 doi: 10.1111/jdv.12504. PMID: 25074680

See all (505)

Clinical prediction guides

Effectiveness of different treatments for odontogenic keratocyst: a network meta-analysis.

Al-Moraissi EA, Kaur A, Gomez RS, Ellis E 3rd
Int J Oral Maxillofac Surg 2023 Jan;52(1):32-43. Epub 2022 Sep 21 doi: 10.1016/j.ijom.2022.09.004. PMID: 36150944

How effective is 5-Fluorouracil as an adjuvant in the management of odontogenic keratocyst? A systematic review and meta-analysis.

Singh AK, Khanal N, Chaulagain R, Bhujel N, Singh RP
Br J Oral Maxillofac Surg 2022 Jul;60(6):746-754. Epub 2022 Feb 17 doi: 10.1016/j.bjoms.2022.02.001. PMID: 35314081

Ameloblastoma: A succinct review of the classification, genetic understanding and novel molecular targeted therapies.

Shi HA, Ng CWB, Kwa CT, Sim QXC
Surgeon 2021 Aug;19(4):238-243. Epub 2020 Jul 22 doi: 10.1016/j.surge.2020.06.009. PMID: 32712102

Odontogenic keratocyst of the mandible: A case report and literature review.

Polak K, Jędrusik-Pawłowska M, Drozdzowska B, Morawiec T
Dent Med Probl 2019 Oct-Dec;56(4):433-436. doi: 10.17219/dmp/110682. PMID: 31689015

Chondroma of the Tongue.

Dimitrijevic MV, Sopta J, Ivisevic TB, Dudvarski Z
J Craniofac Surg 2019 Jun;30(4):e315-e317. doi: 10.1097/SCS.0000000000005230. PMID: 30845089

See all (383)

Recent systematic reviews

Effectiveness of molecular-targeted chemotherapy in ameloblastomas: A systematic review.

Yoithapprabhunath TR, Srichinthu KK, Gupta D, Singh D, Pasupuleti S, Nirmal RM
Indian J Dent Res 2022 Jul-Sep;33(3):323-331. doi: 10.4103/ijdr.ijdr_456_22. PMID: 36656197

How effective is 5-Fluorouracil as an adjuvant in the management of odontogenic keratocyst? A systematic review and meta-analysis.

Singh AK, Khanal N, Chaulagain R, Bhujel N, Singh RP
Br J Oral Maxillofac Surg 2022 Jul;60(6):746-754. Epub 2022 Feb 17 doi: 10.1016/j.bjoms.2022.02.001. PMID: 35314081

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Odontogenic and Maxillofacial Bone Tumours.

Vered M, Wright JM
Head Neck Pathol 2022 Mar;16(1):63-75. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01404-7. PMID: 35312978 Free PMC Article

Benign fibrous histiocytoma of the oral and maxillofacial region: A systematic review.

Kirschnick LB, Schuch LF, Silveira FM, Só BB, Martins MAT, Lopes MA, Vargas PA, Santos-Silva AR, Carrard VC, Vasconcelos ACU, Wagner VP, Martins MD
Oral Surg Oral Med Oral Pathol Oral Radiol 2022 Feb;133(2):e43-e56. Epub 2021 Jul 15 doi: 10.1016/j.oooo.2021.07.003. PMID: 34511357

Surgical interventions for management of benign parotid tumors: Systematic review and network meta-analysis.

Mashrah MA, Al-Sharani HM, Al-Aroomi MA, Abdelrehem A, Aldhohrah T, Wang L
Head Neck 2021 Nov;43(11):3631-3645. Epub 2021 Jul 20 doi: 10.1002/hed.26813. PMID: 34288212

See all (41)

MedGen

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Benign Maxillofacial Neoplasm

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Related information

Recent activity