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Uveal cancer

MedGen UID:
1772018
•Concept ID:
C3665670
•
Neoplastic Process
Synonyms: cancer of uvea; Malignant Neoplasm of the Uvea; malignant neoplasm of the uvea; Malignant Neoplasm of Uvea; malignant neoplasm of uvea; Malignant Tumor of the Uvea; malignant tumor of the uvea; Malignant Tumor of Uvea; malignant tumor of uvea; malignant tumour of the uvea; malignant tumour of uvea; Malignant Uvea Neoplasm; malignant uvea neoplasm; Malignant Uvea Tumor; malignant uvea tumor; malignant uvea tumour; Malignant Uveal Neoplasm; malignant uveal neoplasm; Malignant Uveal Tract Neoplasm; Malignant Uveal Tumor; malignant uveal tumor; malignant uveal tumour; uvea cancer; uveal cancer
 
Monarch Initiative: MONDO:0002659

Definition

A primary or metastatic malignant neoplasm that affects the choroid, ciliary body, or iris. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUveal cancer

Professional guidelines

PubMed

Advances in the clinical management of uveal melanoma.
Carvajal RD, Sacco JJ, Jager MJ, Eschelman DJ, Olofsson Bagge R, Harbour JW, Chieng ND, Patel SP, Joshua AM, Piperno-Neumann S
Nat Rev Clin Oncol 2023 Feb;20(2):99-115. Epub 2023 Jan 4 doi: 10.1038/s41571-022-00714-1. PMID: 36600005
Metastatic disease from uveal melanoma: treatment options and future prospects.
Carvajal RD, Schwartz GK, Tezel T, Marr B, Francis JH, Nathan PD
Br J Ophthalmol 2017 Jan;101(1):38-44. Epub 2016 Aug 29 doi: 10.1136/bjophthalmol-2016-309034. PMID: 27574175Free PMC Article
Uveal melanoma: From diagnosis to treatment and the science in between.
Chattopadhyay C, Kim DW, Gombos DS, Oba J, Qin Y, Williams MD, Esmaeli B, Grimm EA, Wargo JA, Woodman SE, Patel SP
Cancer 2016 Aug 1;122(15):2299-312. Epub 2016 Mar 15 doi: 10.1002/cncr.29727. PMID: 26991400Free PMC Article

Recent clinical studies

Diagnosis

Heterogeneity and molecular landscape of melanoma: implications for targeted therapy.
Beigi YZ, Lanjanian H, Fayazi R, Salimi M, Hoseyni BHM, Noroozizadeh MH, Masoudi-Nejad A
Mol Biomed 2024 May 10;5(1):17. doi: 10.1186/s43556-024-00182-2. PMID: 38724687Free PMC Article

Therapy

One-stage and two-stage designs for phase II clinical trials with survival endpoints.
Whitehead J
Stat Med 2014 Sep 28;33(22):3830-43. Epub 2014 May 12 doi: 10.1002/sim.6196. PMID: 24817473

Prognosis

Heterogeneity and molecular landscape of melanoma: implications for targeted therapy.
Beigi YZ, Lanjanian H, Fayazi R, Salimi M, Hoseyni BHM, Noroozizadeh MH, Masoudi-Nejad A
Mol Biomed 2024 May 10;5(1):17. doi: 10.1186/s43556-024-00182-2. PMID: 38724687Free PMC Article

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    Clinical resources

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