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Abnormal gametogenesis

MedGen UID:
1779633
Concept ID:
C5539524
Cell or Molecular Dysfunction
HPO: HP:0033337

Definition

An anomaly in the process by a a haploid cell is formed from a diploid cells through meiosis. In males, diploid spermatogonia produce two haploid cells (secondary spermatocytes) in meiosis I and four haploid spermatids in meiosis II. In females, primordial germ cells under meiosis II before birth to form primary oocytes. Once puberty cell begins, these cells form secondary oocytes through meiosis II. [from HPO]

Professional guidelines

PubMed

Shao Y, Li J, Lu J, Li H, Zhu Y, Jiang W, Yan J
Reprod Biol Endocrinol 2020 Aug 5;18(1):79. doi: 10.1186/s12958-020-00635-7. PMID: 32758287Free PMC Article

Recent clinical studies

Etiology

Shao Y, Li J, Lu J, Li H, Zhu Y, Jiang W, Yan J
Reprod Biol Endocrinol 2020 Aug 5;18(1):79. doi: 10.1186/s12958-020-00635-7. PMID: 32758287Free PMC Article
Steigrad SJ
Best Pract Res Clin Obstet Gynaecol 2003 Dec;17(6):837-47. doi: 10.1016/s1521-6934(03)00049-x. PMID: 14614884
Grimes DA
Am J Obstet Gynecol 1984 Oct 1;150(3):309-18. doi: 10.1016/s0002-9378(84)90370-3. PMID: 6091460

Diagnosis

Steigrad SJ
Best Pract Res Clin Obstet Gynaecol 2003 Dec;17(6):837-47. doi: 10.1016/s1521-6934(03)00049-x. PMID: 14614884

Therapy

Shao Y, Li J, Lu J, Li H, Zhu Y, Jiang W, Yan J
Reprod Biol Endocrinol 2020 Aug 5;18(1):79. doi: 10.1186/s12958-020-00635-7. PMID: 32758287Free PMC Article

Prognosis

Steigrad SJ
Best Pract Res Clin Obstet Gynaecol 2003 Dec;17(6):837-47. doi: 10.1016/s1521-6934(03)00049-x. PMID: 14614884

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