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Breast Classic Lobular Carcinoma In Situ Type B

MedGen UID:
1783712
•Concept ID:
C5447985
•
Neoplastic Process

Definition

Breast classic lobular carcinoma in situ characterized by the presence of neoplastic cells with nuclei of various sizes and shapes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBreast Classic Lobular Carcinoma In Situ Type B

Recent clinical studies

Etiology

Loss of cellular cohesion in cytology composes a special subgroup of breast tumors - analysis of 37 cases.
Wakasa T, Nakamura M, Kagiya T, Taniguchi E, Sakurai T, Kakudo K
Acta Cytol 2014;58(1):89-95. Epub 2013 Dec 10 doi: 10.1159/000356405. PMID: 24334922
The predictive power of semiquantitative immunohistochemical assessment of p53 and c-erb B-2 in lymph node-negative breast cancer.
O'Malley FP, Saad Z, Kerkvliet N, Doig G, Stitt L, Ainsworth P, Hundal H, Chambers AF, Turnbull DI, Bramwell V
Hum Pathol 1996 Sep;27(9):955-63. doi: 10.1016/s0046-8177(96)90224-5. PMID: 8816892

Diagnosis

The predictive power of semiquantitative immunohistochemical assessment of p53 and c-erb B-2 in lymph node-negative breast cancer.
O'Malley FP, Saad Z, Kerkvliet N, Doig G, Stitt L, Ainsworth P, Hundal H, Chambers AF, Turnbull DI, Bramwell V
Hum Pathol 1996 Sep;27(9):955-63. doi: 10.1016/s0046-8177(96)90224-5. PMID: 8816892

Prognosis

The predictive power of semiquantitative immunohistochemical assessment of p53 and c-erb B-2 in lymph node-negative breast cancer.
O'Malley FP, Saad Z, Kerkvliet N, Doig G, Stitt L, Ainsworth P, Hundal H, Chambers AF, Turnbull DI, Bramwell V
Hum Pathol 1996 Sep;27(9):955-63. doi: 10.1016/s0046-8177(96)90224-5. PMID: 8816892
c-erbB-2 overexpression and histological type of in situ and invasive breast carcinoma.
Somerville JE, Clarke LA, Biggart JD
J Clin Pathol 1992 Jan;45(1):16-20. doi: 10.1136/jcp.45.1.16. PMID: 1346789Free PMC Article

Clinical prediction guides

Loss of cellular cohesion in cytology composes a special subgroup of breast tumors - analysis of 37 cases.
Wakasa T, Nakamura M, Kagiya T, Taniguchi E, Sakurai T, Kakudo K
Acta Cytol 2014;58(1):89-95. Epub 2013 Dec 10 doi: 10.1159/000356405. PMID: 24334922
The predictive power of semiquantitative immunohistochemical assessment of p53 and c-erb B-2 in lymph node-negative breast cancer.
O'Malley FP, Saad Z, Kerkvliet N, Doig G, Stitt L, Ainsworth P, Hundal H, Chambers AF, Turnbull DI, Bramwell V
Hum Pathol 1996 Sep;27(9):955-63. doi: 10.1016/s0046-8177(96)90224-5. PMID: 8816892

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