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Lacrimal Drainage System Carcinoma

MedGen UID:
1784930
•Concept ID:
C5446447
•
Neoplastic Process
Synonym: Carcinoma of the Lacrimal Drainage System

Definition

A carcinoma that arises from the lacrimal sac, canaliculi, or nasolacrimal duct. [from NCI]

Professional guidelines

PubMed

Evaluation and Management of Chemotherapy-Induced Epiphora, Punctal and Canalicular Stenosis, and Nasolacrimal Duct Obstruction.
Mansur C, Pfeiffer ML, Esmaeli B
Ophthalmic Plast Reconstr Surg 2017 Jan/Feb;33(1):9-12. doi: 10.1097/IOP.0000000000000745. PMID: 27429222
Clinical features and management of tumors affecting the lacrimal drainage apparatus.
Valenzuela AA, McNab AA, Selva D, O'Donnell BA, Whitehead KJ, Sullivan TJ
Ophthalmic Plast Reconstr Surg 2006 Mar-Apr;22(2):96-101. doi: 10.1097/01.iop.0000198457.71173.7b. PMID: 16550051
The role of lacrimal intubation in the management of facial trauma and tumor resection.
Spinelli HM, Shapiro MD, Wei LL, Elahi E, Hirmand H
Plast Reconstr Surg 2005 Jun;115(7):1871-6. doi: 10.1097/01.prs.0000164687.41948.62. PMID: 15923831

Recent clinical studies

Etiology

Holding back the tears: is there a role for marsupialisation?
Chiu SJ, Currie ZI, Tan JH
BMJ Open Ophthalmol 2022 Aug;7(1) doi: 10.1136/bmjophth-2022-000985. PMID: 36161857Free PMC Article
Human Papillomavirus Related Neoplasia of the Ocular Adnexa.
Ramberg I, Heegaard S
Viruses 2021 Aug 2;13(8) doi: 10.3390/v13081522. PMID: 34452388Free PMC Article
Carcinomas of the lacrimal drainage system.
Ramberg I, Toft PB, Heegaard S
Surv Ophthalmol 2020 Nov-Dec;65(6):691-707. Epub 2020 Apr 15 doi: 10.1016/j.survophthal.2020.04.001. PMID: 32304675
Lacrimal Sac Sebaceous Carcinoma.
Vahdani K, Coupland SE, Ashdown ME, Garrott H, Ford R
Ophthalmic Plast Reconstr Surg 2019 Jul/Aug;35(4):e89-e91. doi: 10.1097/IOP.0000000000001386. PMID: 30921057
Tumors of the lacrimal drainage system.
Heindl LM, Jünemann AG, Kruse FE, Holbach LM
Orbit 2010 Oct;29(5):298-306. doi: 10.3109/01676830.2010.492887. PMID: 20958177

Diagnosis

Clinical profile and management outcomes of lacrimal drainage system malignancies.
Alam MS, Mukherjee B, Krishnakumar S
Orbit 2022 Aug;41(4):429-436. Epub 2021 May 21 doi: 10.1080/01676830.2021.1925932. PMID: 34018461
Human Papillomavirus Related Neoplasia of the Ocular Adnexa.
Ramberg I, Heegaard S
Viruses 2021 Aug 2;13(8) doi: 10.3390/v13081522. PMID: 34452388Free PMC Article
Primary Malignant Epithelial Tumors of the Lacrimal Drainage System: A Major Review.
Singh S, Ali MJ
Orbit 2021 Jun;40(3):179-192. Epub 2020 Jun 8 doi: 10.1080/01676830.2020.1769684. PMID: 32506982
Carcinomas of the lacrimal drainage system.
Ramberg I, Toft PB, Heegaard S
Surv Ophthalmol 2020 Nov-Dec;65(6):691-707. Epub 2020 Apr 15 doi: 10.1016/j.survophthal.2020.04.001. PMID: 32304675
Lacrimal Sac Sebaceous Carcinoma.
Vahdani K, Coupland SE, Ashdown ME, Garrott H, Ford R
Ophthalmic Plast Reconstr Surg 2019 Jul/Aug;35(4):e89-e91. doi: 10.1097/IOP.0000000000001386. PMID: 30921057

Therapy

Postoncological lacrimal duct reconstruction: A practical classification system for reconstructive planning and short-term results of a case series.
van Burink MV, Rakhorst HA, van Couwelaar GM, Schmidbauer U
J Plast Reconstr Aesthet Surg 2018 Dec;71(12):1796-1803. Epub 2018 Aug 3 doi: 10.1016/j.bjps.2018.07.024. PMID: 30213744
Evaluation and Management of Chemotherapy-Induced Epiphora, Punctal and Canalicular Stenosis, and Nasolacrimal Duct Obstruction.
Mansur C, Pfeiffer ML, Esmaeli B
Ophthalmic Plast Reconstr Surg 2017 Jan/Feb;33(1):9-12. doi: 10.1097/IOP.0000000000000745. PMID: 27429222
Iodine-131 Therapy and Lacrimal Drainage System Toxicity: Nasal Localization Studies Using Whole Body Nuclear Scintigraphy and SPECT-CT.
Ali MJ, Vyakaranam AR, Rao JE, Prasad G, Reddy PV
Ophthalmic Plast Reconstr Surg 2017 Jan/Feb;33(1):13-16. doi: 10.1097/IOP.0000000000000603. PMID: 26669292
Nasolacrimal drainage obstruction after radioiodine therapy: case report and a review of the literature.
Brockmann H, Wilhelm K, Joe A, Palmedo H, Biersack HJ
Clin Nucl Med 2005 Aug;30(8):543-5. doi: 10.1097/01.rlu.0000170013.84378.2a. PMID: 16024949
Nasolacrimal drainage system obstruction from radioactive iodine therapy for thyroid carcinoma.
Kloos RT, Duvuuri V, Jhiang SM, Cahill KV, Foster JA, Burns JA
J Clin Endocrinol Metab 2002 Dec;87(12):5817-20. doi: 10.1210/jc.2002-020210. PMID: 12466391

Prognosis

Human papillomavirus-related neoplasia of the ocular adnexa.
Ramberg IMS
Acta Ophthalmol 2022 Oct;100 Suppl 272(Suppl 272):3-33. doi: 10.1111/aos.15244. PMID: 36203222Free PMC Article
Human Papillomavirus Related Neoplasia of the Ocular Adnexa.
Ramberg I, Heegaard S
Viruses 2021 Aug 2;13(8) doi: 10.3390/v13081522. PMID: 34452388Free PMC Article
Primary Malignant Epithelial Tumors of the Lacrimal Drainage System: A Major Review.
Singh S, Ali MJ
Orbit 2021 Jun;40(3):179-192. Epub 2020 Jun 8 doi: 10.1080/01676830.2020.1769684. PMID: 32506982
Combined External, Endoscopic, Endonasal-Assisted En Bloc Resection of Malignant Tumors From the Lacrimal Drainage System.
Shi J, Tu Y, Wu W
J Craniofac Surg 2018 Oct;29(7):1855-1858. doi: 10.1097/SCS.0000000000004655. PMID: 29944561
Tumors of the lacrimal drainage system.
Heindl LM, Jünemann AG, Kruse FE, Holbach LM
Orbit 2010 Oct;29(5):298-306. doi: 10.3109/01676830.2010.492887. PMID: 20958177

Clinical prediction guides

Human papillomavirus-related neoplasia of the ocular adnexa.
Ramberg IMS
Acta Ophthalmol 2022 Oct;100 Suppl 272(Suppl 272):3-33. doi: 10.1111/aos.15244. PMID: 36203222Free PMC Article
Human Papillomavirus Related Neoplasia of the Ocular Adnexa.
Ramberg I, Heegaard S
Viruses 2021 Aug 2;13(8) doi: 10.3390/v13081522. PMID: 34452388Free PMC Article
Vismodegib for Preservation of Visual Function in Patients with Advanced Periocular Basal Cell Carcinoma: The VISORB Trial.
Kahana A, Unsworth SP, Andrews CA, Chan MP, Bresler SC, Bichakjian CK, Durham AB, Demirci H, Elner VM, Nelson CC, Kim DS, Joseph SS, Swiecicki PL, Worden FP
Oncologist 2021 Jul;26(7):e1240-e1249. Epub 2021 May 31 doi: 10.1002/onco.13820. PMID: 33988881Free PMC Article
Nasolacrimal duct obstruction caused by oncocytic carcinoma.
Jung JH, Shin DH, Cho KS, Choi HY
Korean J Ophthalmol 2013 Apr;27(2):126-9. Epub 2013 Feb 27 doi: 10.3341/kjo.2013.27.2.126. PMID: 23543280Free PMC Article
Nasolacrimal duct obstruction: clinicopathologic analysis of 205 cases.
Altan-Yaycioglu R, Canan H, Sizmaz S, Bal N, Pelit A, Akova YA
Orbit 2010 Oct;29(5):254-8. Epub 2010 Aug 12 doi: 10.3109/01676831003739699. PMID: 20704489

Recent systematic reviews

Holding back the tears: is there a role for marsupialisation?
Chiu SJ, Currie ZI, Tan JH
BMJ Open Ophthalmol 2022 Aug;7(1) doi: 10.1136/bmjophth-2022-000985. PMID: 36161857Free PMC Article

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