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Uterine Corpus Myxoid Smooth Muscle Tumor of Uncertain Malignant Potential

MedGen UID:
1792895
•Concept ID:
C5556454
•
Neoplastic Process
Synonym: Uterine Corpus Myxoid STUMP

Definition

A smooth muscle tumor of uncertain malignant potential that arises from the uterine corpus and displays myxoid changes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUterine Corpus Myxoid Smooth Muscle Tumor of Uncertain Malignant Potential

Recent clinical studies

Etiology

ALK Immunoexpression is Specific for Inflammatory Myofibroblastic Tumor Among Vulvovaginal Mesenchymal Neoplasms.
Bowman CJ, Medeiros F, Fadare O, Sangoi AR, Horvai AE, Devine WP, McCluggage WG, Rabban JT
Int J Gynecol Pathol 2023 Jan 1;42(1):1-10. Epub 2022 Feb 18 doi: 10.1097/PGP.0000000000000858. PMID: 35180768

Diagnosis

A Case of Uterine Tumor Resembling Ovarian Sex Cord Tumor With Prominent Myxoid Features.
Ise K, Tanei ZI, Oda Y, Tanikawa S, Sugino H, Ishida Y, Tsuda M, Gotoda Y, Nishiwaki K, Yanai H, Hasegawa T, Nagashima K, Tanaka S
Int J Gynecol Pathol 2024 Jan 1;43(1):41-46. Epub 2023 Jun 14 doi: 10.1097/PGP.0000000000000949. PMID: 37406360
ALK Immunoexpression is Specific for Inflammatory Myofibroblastic Tumor Among Vulvovaginal Mesenchymal Neoplasms.
Bowman CJ, Medeiros F, Fadare O, Sangoi AR, Horvai AE, Devine WP, McCluggage WG, Rabban JT
Int J Gynecol Pathol 2023 Jan 1;42(1):1-10. Epub 2022 Feb 18 doi: 10.1097/PGP.0000000000000858. PMID: 35180768
ALK Is a Specific Diagnostic Marker for Inflammatory Myofibroblastic Tumor of the Uterus.
Mohammad N, Haimes JD, Mishkin S, Kudlow BA, Leong MY, Chew SH, Koay E, Whitehouse A, Cope N, Ali RH, Köbel M, Stewart CJR, McCluggage WG, Lee CH
Am J Surg Pathol 2018 Oct;42(10):1353-1359. doi: 10.1097/PAS.0000000000001120. PMID: 30015720
Myxoid mixed low-grade endometrial stromal sarcoma and smooth muscle tumor of the uterus. Case report.
Dundr P, Fischerová D, Povýšil C, Cibula D, Zikán M
Cesk Patol 2012 Apr;48(2):103-6. PMID: 22716064
Pleomorphic rhabdomyosarcoma of the uterine corpus: a clinicopathologic study of 4 cases and a review of the literature.
Fadare O, Bonvicino A, Martel M, Renshaw IL, Azodi M, Parkash V
Int J Gynecol Pathol 2010 Mar;29(2):122-34. doi: 10.1097/PGP.0b013e3181bc98c0. PMID: 20173498

Prognosis

ALK Is a Specific Diagnostic Marker for Inflammatory Myofibroblastic Tumor of the Uterus.
Mohammad N, Haimes JD, Mishkin S, Kudlow BA, Leong MY, Chew SH, Koay E, Whitehouse A, Cope N, Ali RH, Köbel M, Stewart CJR, McCluggage WG, Lee CH
Am J Surg Pathol 2018 Oct;42(10):1353-1359. doi: 10.1097/PAS.0000000000001120. PMID: 30015720
Pleomorphic rhabdomyosarcoma of the uterine corpus: a clinicopathologic study of 4 cases and a review of the literature.
Fadare O, Bonvicino A, Martel M, Renshaw IL, Azodi M, Parkash V
Int J Gynecol Pathol 2010 Mar;29(2):122-34. doi: 10.1097/PGP.0b013e3181bc98c0. PMID: 20173498
An endometrial stromal tumor with osteoclast-like giant cells.
Fadare O, McCalip B, Mariappan MR, Hileeto D, Parkash V
Ann Diagn Pathol 2005 Jun;9(3):160-5. doi: 10.1016/j.anndiagpath.2005.03.002. PMID: 15944960

Clinical prediction guides

ALK Is a Specific Diagnostic Marker for Inflammatory Myofibroblastic Tumor of the Uterus.
Mohammad N, Haimes JD, Mishkin S, Kudlow BA, Leong MY, Chew SH, Koay E, Whitehouse A, Cope N, Ali RH, Köbel M, Stewart CJR, McCluggage WG, Lee CH
Am J Surg Pathol 2018 Oct;42(10):1353-1359. doi: 10.1097/PAS.0000000000001120. PMID: 30015720
Inflammatory myofibroblastic tumor of the uterus with prominent myxoid change.
Shintaku M, Fukushima A
Pathol Int 2006 Oct;56(10):625-8. doi: 10.1111/j.1440-1827.2006.02018.x. PMID: 16984620

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