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Skene Gland Adenocarcinoma of the Urethra

MedGen UID:
1793183
•Concept ID:
C5556742
•
Neoplastic Process
Synonym: Urethral Adenocarcinoma of Skene Gland Origin

Definition

A rare urethral adenocarcinoma arising from the Skene gland. It is characterized by morphological and immunohistochemical features similar to prostate adenocarcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSkene Gland Adenocarcinoma of the Urethra

Recent clinical studies

Etiology

Reprint of: Female Urethral Carcinoma: A contemporary review of the clinicopathologic features, with emphasis on the histo-anatomic landmarks and potential staging issues.
Lagarde-Lenon MS, Aron M
Hum Pathol 2023 Mar;133:126-135. Epub 2023 Mar 7 doi: 10.1016/j.humpath.2023.02.011. PMID: 36894368
Management of Primary Female Urethral Adenocarcinoma: Two Rare Case Reports and Literature Review.
Tian J, Zhu T, Xu Z, Chen X, Wu Y, Fu G, Jin B
Medicina (Kaunas) 2023 Jan 4;59(1) doi: 10.3390/medicina59010109. PMID: 36676733Free PMC Article
Female urethral carcinoma: a contemporary review of the clinicopathologic features, with emphasis on the histoanatomic landmarks and potential staging issues.
Lagarde-Lenon MS, Aron M
Hum Pathol 2022 Nov;129:71-80. Epub 2022 Aug 28 doi: 10.1016/j.humpath.2022.08.003. PMID: 36037997
Primary adenocarcinomas of the vulva and related structures: An enigmatic and diverse group of tumors(✰).
Desouki MM, Fadare O
Semin Diagn Pathol 2021 Jan;38(1):71-84. Epub 2020 Sep 25 doi: 10.1053/j.semdp.2020.09.011. PMID: 33032903
Female Urethra Adenocarcinoma.
Dell'Atti L, Galosi AB
Clin Genitourin Cancer 2018 Apr;16(2):e263-e267. Epub 2017 Oct 16 doi: 10.1016/j.clgc.2017.10.006. PMID: 29113768

Diagnosis

Reprint of: Female Urethral Carcinoma: A contemporary review of the clinicopathologic features, with emphasis on the histo-anatomic landmarks and potential staging issues.
Lagarde-Lenon MS, Aron M
Hum Pathol 2023 Mar;133:126-135. Epub 2023 Mar 7 doi: 10.1016/j.humpath.2023.02.011. PMID: 36894368
Female urethral carcinoma: a contemporary review of the clinicopathologic features, with emphasis on the histoanatomic landmarks and potential staging issues.
Lagarde-Lenon MS, Aron M
Hum Pathol 2022 Nov;129:71-80. Epub 2022 Aug 28 doi: 10.1016/j.humpath.2022.08.003. PMID: 36037997
First Molecular Genetic Characterization of Skene's Gland Adenocarcinoma.
Lenz J, Michal M, Michal M, Hes O, Konečná P, Lenz D
Int J Surg Pathol 2021 Jun;29(4):447-453. Epub 2020 Aug 14 doi: 10.1177/1066896920947808. PMID: 32795117
A rare case of primary female urethral adenocarcinoma: Columnar type with colonic adenocarcinoma features.
Gangadhar P, Pai MR, Sandhya I
Indian J Pathol Microbiol 2018 Jan-Mar;61(1):127-130. doi: 10.4103/IJPM.IJPM_745_16. PMID: 29567902
Female Urethra Adenocarcinoma.
Dell'Atti L, Galosi AB
Clin Genitourin Cancer 2018 Apr;16(2):e263-e267. Epub 2017 Oct 16 doi: 10.1016/j.clgc.2017.10.006. PMID: 29113768

Prognosis

Reprint of: Female Urethral Carcinoma: A contemporary review of the clinicopathologic features, with emphasis on the histo-anatomic landmarks and potential staging issues.
Lagarde-Lenon MS, Aron M
Hum Pathol 2023 Mar;133:126-135. Epub 2023 Mar 7 doi: 10.1016/j.humpath.2023.02.011. PMID: 36894368
Female urethral carcinoma: a contemporary review of the clinicopathologic features, with emphasis on the histoanatomic landmarks and potential staging issues.
Lagarde-Lenon MS, Aron M
Hum Pathol 2022 Nov;129:71-80. Epub 2022 Aug 28 doi: 10.1016/j.humpath.2022.08.003. PMID: 36037997
First Molecular Genetic Characterization of Skene's Gland Adenocarcinoma.
Lenz J, Michal M, Michal M, Hes O, Konečná P, Lenz D
Int J Surg Pathol 2021 Jun;29(4):447-453. Epub 2020 Aug 14 doi: 10.1177/1066896920947808. PMID: 32795117
Highlighting the importance of multidisciplinary approach: A rare case of primary periurethral poorly differentiated carcinoma.
Kalinderi K, Kalinderis M, Linos K, Salpigidis G, Papanikolaou E, Chalkidou M, Mykoniou A, Flaris N, Papazisis K, Athanasiadis A, Kalogiannidis I
Taiwan J Obstet Gynecol 2020 Jan;59(1):150-153. doi: 10.1016/j.tjog.2019.11.025. PMID: 32039785
Female Urethra Adenocarcinoma.
Dell'Atti L, Galosi AB
Clin Genitourin Cancer 2018 Apr;16(2):e263-e267. Epub 2017 Oct 16 doi: 10.1016/j.clgc.2017.10.006. PMID: 29113768

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