U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ampulla of Vater Tubulovillous Adenoma

MedGen UID:
231058
•Concept ID:
C1332253
•
Neoplastic Process

Definition

An intestinal-type adenoma arising from the ampulla of Vater. It is characterized by the presence of tubular and villous epithelial structures and it is associated with dysplasia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAmpulla of Vater Tubulovillous Adenoma

Recent clinical studies

Etiology

Endoscopic papillectomy or pancreaticoduodenectomy for ampullary lesions: a single center retrospective cohort study.
Seyfried S, Kähler G, Belle S, Hirsch D, Reißfelder C, Rahbari N, Hardt J
Scand J Gastroenterol 2022 Nov;57(11):1381-1389. Epub 2022 Jun 18 doi: 10.1080/00365521.2022.2088243. PMID: 35723057
Adenomas of the ampulla of Vater: a comparison of outcomes of operative and endoscopic resections.
Onkendi EO, Naik ND, Rosedahl JK, Harmsen SW, Gostout CJ, Baron TH Sr, Sarr MG, Que FG
J Gastrointest Surg 2014 Sep;18(9):1588-96. Epub 2014 Jun 11 doi: 10.1007/s11605-014-2543-z. PMID: 24916584
Adenoma of the papilla and ampulla--premalignant lesions?
Wittekind C, Tannapfel A
Langenbecks Arch Surg 2001 Apr;386(3):172-5. doi: 10.1007/s004230100234. PMID: 11382317
Local resection of benign periampullary tumors.
Treitschke F, Beger HG
Ann Oncol 1999;10 Suppl 4:212-4. PMID: 10436825
Ampullectomy for adenoma of the papilla and ampulla of Vater.
Beger HG, Staib L, Schoenberg MH
Langenbecks Arch Surg 1998 Apr;383(2):190-3. doi: 10.1007/s004230050117. PMID: 9641898

Diagnosis

Endoscopic pancreaticobiliary drainage with overlength stents to prevent delayed perforation after endoscopic papillectomy: A pilot study.
Wu L, Liu F, Zhang N, Wang XP, Li W
World J Gastroenterol 2020 Nov 28;26(44):7036-7045. doi: 10.3748/wjg.v26.i44.7036. PMID: 33311948Free PMC Article
Ampullary Adenoma Treated by Endoscopic Double-Snare Retracting Papillectomy.
Soma H, Miyata N, Hozawa S, Higuchi H, Yamagishi Y, Nakamura Y, Saeki K, Kameyama K, Masugi Y, Yahagi N, Kanai T
Gut Liver 2015 Sep 23;9(5):689-92. doi: 10.5009/gnl14206. PMID: 26087781Free PMC Article
Endoscopic ultrasound evaluation in the surgical treatment of duodenal and peri-ampullary adenomas.
Azih LC, Broussard BL, Phadnis MA, Heslin MJ, Eloubeidi MA, Varadarajulu S, Arnoletti JP
World J Gastroenterol 2013 Jan 28;19(4):511-5. doi: 10.3748/wjg.v19.i4.511. PMID: 23382629Free PMC Article
Almost all infiltrating colloid carcinomas of the pancreas and periampullary region arise from in situ papillary neoplasms: a study of 39 cases.
Seidel G, Zahurak M, Iacobuzio-Donahue C, Sohn TA, Adsay NV, Yeo CJ, Lillemoe KD, Cameron JL, Hruban RH, Wilentz RE
Am J Surg Pathol 2002 Jan;26(1):56-63. doi: 10.1097/00000478-200201000-00006. PMID: 11756769
Wide ampullectomy for patients with villous adenoma of duodenal papilla and follow-up results of pancreaticobiliary tract.
Chijiiwa K, Yamashita H, Kuroki S
Int Surg 1994 Apr-Jun;79(2):178-82. PMID: 7928158

Therapy

Ampullary Adenoma Treated by Endoscopic Double-Snare Retracting Papillectomy.
Soma H, Miyata N, Hozawa S, Higuchi H, Yamagishi Y, Nakamura Y, Saeki K, Kameyama K, Masugi Y, Yahagi N, Kanai T
Gut Liver 2015 Sep 23;9(5):689-92. doi: 10.5009/gnl14206. PMID: 26087781Free PMC Article
Adenomas of the ampulla of Vater: a comparison of outcomes of operative and endoscopic resections.
Onkendi EO, Naik ND, Rosedahl JK, Harmsen SW, Gostout CJ, Baron TH Sr, Sarr MG, Que FG
J Gastrointest Surg 2014 Sep;18(9):1588-96. Epub 2014 Jun 11 doi: 10.1007/s11605-014-2543-z. PMID: 24916584

Prognosis

Adenomas of the ampulla of Vater: a comparison of outcomes of operative and endoscopic resections.
Onkendi EO, Naik ND, Rosedahl JK, Harmsen SW, Gostout CJ, Baron TH Sr, Sarr MG, Que FG
J Gastrointest Surg 2014 Sep;18(9):1588-96. Epub 2014 Jun 11 doi: 10.1007/s11605-014-2543-z. PMID: 24916584
Endoscopic ultrasound evaluation in the surgical treatment of duodenal and peri-ampullary adenomas.
Azih LC, Broussard BL, Phadnis MA, Heslin MJ, Eloubeidi MA, Varadarajulu S, Arnoletti JP
World J Gastroenterol 2013 Jan 28;19(4):511-5. doi: 10.3748/wjg.v19.i4.511. PMID: 23382629Free PMC Article
Almost all infiltrating colloid carcinomas of the pancreas and periampullary region arise from in situ papillary neoplasms: a study of 39 cases.
Seidel G, Zahurak M, Iacobuzio-Donahue C, Sohn TA, Adsay NV, Yeo CJ, Lillemoe KD, Cameron JL, Hruban RH, Wilentz RE
Am J Surg Pathol 2002 Jan;26(1):56-63. doi: 10.1097/00000478-200201000-00006. PMID: 11756769
Ampullectomy for adenoma of the papilla and ampulla of Vater.
Beger HG, Staib L, Schoenberg MH
Langenbecks Arch Surg 1998 Apr;383(2):190-3. doi: 10.1007/s004230050117. PMID: 9641898
Wide ampullectomy for patients with villous adenoma of duodenal papilla and follow-up results of pancreaticobiliary tract.
Chijiiwa K, Yamashita H, Kuroki S
Int Surg 1994 Apr-Jun;79(2):178-82. PMID: 7928158

Clinical prediction guides

Ampullary Adenoma Treated by Endoscopic Double-Snare Retracting Papillectomy.
Soma H, Miyata N, Hozawa S, Higuchi H, Yamagishi Y, Nakamura Y, Saeki K, Kameyama K, Masugi Y, Yahagi N, Kanai T
Gut Liver 2015 Sep 23;9(5):689-92. doi: 10.5009/gnl14206. PMID: 26087781Free PMC Article
Adenomas of the ampulla of Vater: a comparison of outcomes of operative and endoscopic resections.
Onkendi EO, Naik ND, Rosedahl JK, Harmsen SW, Gostout CJ, Baron TH Sr, Sarr MG, Que FG
J Gastrointest Surg 2014 Sep;18(9):1588-96. Epub 2014 Jun 11 doi: 10.1007/s11605-014-2543-z. PMID: 24916584
Endoscopic ultrasound evaluation in the surgical treatment of duodenal and peri-ampullary adenomas.
Azih LC, Broussard BL, Phadnis MA, Heslin MJ, Eloubeidi MA, Varadarajulu S, Arnoletti JP
World J Gastroenterol 2013 Jan 28;19(4):511-5. doi: 10.3748/wjg.v19.i4.511. PMID: 23382629Free PMC Article
Almost all infiltrating colloid carcinomas of the pancreas and periampullary region arise from in situ papillary neoplasms: a study of 39 cases.
Seidel G, Zahurak M, Iacobuzio-Donahue C, Sohn TA, Adsay NV, Yeo CJ, Lillemoe KD, Cameron JL, Hruban RH, Wilentz RE
Am J Surg Pathol 2002 Jan;26(1):56-63. doi: 10.1097/00000478-200201000-00006. PMID: 11756769

Supplemental Content

Table of contents

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...