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Non-Neoplastic Dental Disorder

MedGen UID:
233769
•Concept ID:
C1335005
•
Disease or Syndrome

Definition

A non-neoplastic disorder that affects the teeth and/or the periodontal tissues. Representative examples include odontoma, enamel hypoplasia, and periodontitis. [from NCI]

Professional guidelines

PubMed

Medication-related osteonecrosis of the jaw: Surgical or non-surgical treatment?
Favia G, Tempesta A, Limongelli L, Crincoli V, Maiorano E
Oral Dis 2018 Mar;24(1-2):238-242. doi: 10.1111/odi.12764. PMID: 29480596
Diagnosis and surgical management of nasopalatine duct cysts.
Aldelaimi TN, Khalil AA
J Craniofac Surg 2012 Sep;23(5):e472-4. doi: 10.1097/SCS.0b013e318258764b. PMID: 22976713
Sialoendoscopy for diagnosis and treatment of non-neoplastic obstruction in the salivary glands.
Danquart J, Wagner N, Arndal H, Homøe P
Dan Med Bull 2011 Feb;58(2):A4232. PMID: 21299921

Recent clinical studies

Etiology

Salivary gland tumours: an epidemiological review of non-neoplastic and neoplastic pathology.
Mckenzie J, Lockyer J, Singh T, Nguyen E
Br J Oral Maxillofac Surg 2023 Jan;61(1):12-18. Epub 2022 Dec 9 doi: 10.1016/j.bjoms.2022.11.281. PMID: 36623970
Histopathologic and clinical outcomes of Milan System categories "non-diagnostic" and "non-neoplastic" of salivary gland fine needle aspirations.
Johnson DN, Antic T, Reeves W, Mueller J, Lastra RR, Cipriani NA, Biernacka A
J Am Soc Cytopathol 2021 Jul-Aug;10(4):349-356. Epub 2021 Mar 19 doi: 10.1016/j.jasc.2021.03.001. PMID: 33867311
Cystic lesions of the parotid gland: radiologic-pathologic correlation according to the latest World Health Organization 2017 Classification of Head and Neck Tumours.
Takita H, Takeshita T, Shimono T, Tanaka H, Iguchi H, Hashimoto S, Kuwae Y, Ohsawa M, Miki Y
Jpn J Radiol 2017 Nov;35(11):629-647. Epub 2017 Aug 23 doi: 10.1007/s11604-017-0678-z. PMID: 28836142
Salivary gland carcinomas.
Ettl T, Schwarz-Furlan S, Gosau M, Reichert TE
Oral Maxillofac Surg 2012 Sep;16(3):267-83. Epub 2012 Jul 29 doi: 10.1007/s10006-012-0350-9. PMID: 22842859
Non-neoplastic salivary gland diseases.
Arduino PG, Carrozzo M, Pentenero M, Bertolusso G, Gandolfo S
Minerva Stomatol 2006 May;55(5):249-70. PMID: 16688102

Diagnosis

CT and MR imaging findings of non-neoplastic cystic lesions of the parotid gland.
Kato H, Kawaguchi M, Ando T, Aoki M, Kuze B, Matsuo M
Jpn J Radiol 2019 Sep;37(9):627-635. Epub 2019 Jul 27 doi: 10.1007/s11604-019-00858-8. PMID: 31352657
Black and Brown: Non-neoplastic Pigmentation of the Oral Mucosa.
Rosebush MS, Briody AN, Cordell KG
Head Neck Pathol 2019 Mar;13(1):47-55. Epub 2019 Jan 22 doi: 10.1007/s12105-018-0980-9. PMID: 30671761Free PMC Article
Cystic lesions of the parotid gland: radiologic-pathologic correlation according to the latest World Health Organization 2017 Classification of Head and Neck Tumours.
Takita H, Takeshita T, Shimono T, Tanaka H, Iguchi H, Hashimoto S, Kuwae Y, Ohsawa M, Miki Y
Jpn J Radiol 2017 Nov;35(11):629-647. Epub 2017 Aug 23 doi: 10.1007/s11604-017-0678-z. PMID: 28836142
Parotid space: anatomic imaging.
Kanekar SG, Mannion K, Zacharia T, Showalter M
Otolaryngol Clin North Am 2012 Dec;45(6):1253-72. doi: 10.1016/j.otc.2012.08.011. PMID: 23153748
Salivary gland carcinomas.
Ettl T, Schwarz-Furlan S, Gosau M, Reichert TE
Oral Maxillofac Surg 2012 Sep;16(3):267-83. Epub 2012 Jul 29 doi: 10.1007/s10006-012-0350-9. PMID: 22842859

Therapy

Medication-related osteonecrosis of the jaw: Surgical or non-surgical treatment?
Favia G, Tempesta A, Limongelli L, Crincoli V, Maiorano E
Oral Dis 2018 Mar;24(1-2):238-242. doi: 10.1111/odi.12764. PMID: 29480596
Quantifying the outcome of surgical treatment of temporomandibular joint ankylosis: A systematic review and meta-analysis.
De Roo N, Van Doorne L, Troch A, Vermeersch H, Brusselaers N
J Craniomaxillofac Surg 2016 Jan;44(1):6-15. Epub 2015 Sep 10 doi: 10.1016/j.jcms.2015.08.019. PMID: 26433770
Differential responses of fibroblasts, non-neoplastic epithelial cells, and oral carcinoma cells to low-level laser therapy.
Schartinger VH, Galvan O, Riechelmann H, Dudás J
Support Care Cancer 2012 Mar;20(3):523-9. Epub 2011 Feb 22 doi: 10.1007/s00520-011-1113-0. PMID: 21340656
Non-neoplastic salivary gland diseases.
Arduino PG, Carrozzo M, Pentenero M, Bertolusso G, Gandolfo S
Minerva Stomatol 2006 May;55(5):249-70. PMID: 16688102
Folate intake and risk of oral and pharyngeal cancer.
Pelucchi C, Talamini R, Negri E, Levi F, Conti E, Franceschi S, La Vecchia C
Ann Oncol 2003 Nov;14(11):1677-81. doi: 10.1093/annonc/mdg448. PMID: 14581278

Prognosis

Histopathologic and clinical outcomes of Milan System categories "non-diagnostic" and "non-neoplastic" of salivary gland fine needle aspirations.
Johnson DN, Antic T, Reeves W, Mueller J, Lastra RR, Cipriani NA, Biernacka A
J Am Soc Cytopathol 2021 Jul-Aug;10(4):349-356. Epub 2021 Mar 19 doi: 10.1016/j.jasc.2021.03.001. PMID: 33867311
Salivary gland carcinomas.
Ettl T, Schwarz-Furlan S, Gosau M, Reichert TE
Oral Maxillofac Surg 2012 Sep;16(3):267-83. Epub 2012 Jul 29 doi: 10.1007/s10006-012-0350-9. PMID: 22842859
Human papilloma virus detection in neoplastic and non-neoplastic nasopharyngeal tissues in Taiwan.
Huang CC, Hsiao JR, Yang MW, Wu YH, Hsu KF, Chang Y, Chen CW, Tsai ST, Wei HP, Jin YT
J Clin Pathol 2011 Jul;64(7):571-7. Epub 2011 Apr 21 doi: 10.1136/jcp.2010.087742. PMID: 21512108
Matrix metalloproteinases and their inhibitors in non-neoplastic otorhinolaryngological disease.
De S, Fenton JE, Jones AS
J Laryngol Otol 2005 Jun;119(6):436-42. doi: 10.1258/0022215054273269. PMID: 15992468
High resolution ultrasound assessment of the parotid gland.
Howlett DC
Br J Radiol 2003 Apr;76(904):271-7. doi: 10.1259/bjr/33081866. PMID: 12711649

Clinical prediction guides

Histopathology of Sinonasal and Nasopharyngeal Neoplastic Lesions in a Tertiary Care Center of Western Nepal: A Descriptive Cross-sectional Study.
Regmi S, Ghosh A, Gharti Magar D, Thapa S, Koirala KP, Talwar OP
JNMA J Nepal Med Assoc 2021 Jul 30;59(239):657-662. doi: 10.31729/jnma.6859. PMID: 34508496Free PMC Article
Salivary Gland Fine Needle Aspiration and Introduction of the Milan Reporting System.
Pusztaszeri M, Rossi ED, Baloch ZW, Faquin WC
Adv Anat Pathol 2019 Mar;26(2):84-92. doi: 10.1097/PAP.0000000000000224. PMID: 30601148
Neoplasms and non-neoplastic pathologies in the oral and maxillofacial regions in children and adolescents of a Brazilian population.
da Silva Barros CC, da Silva LP, Gonzaga AKG, de Medeiros AMC, de Souza LB, da Silveira ÉJD
Clin Oral Investig 2019 Apr;23(4):1587-1593. Epub 2018 Aug 24 doi: 10.1007/s00784-018-2581-0. PMID: 30143900
Agreement between clinical and histopathologic diagnoses and completeness of oral biopsy forms.
Mendez M, Haas AN, Rados PV, Sant'ana M Filho, Carrard VC
Braz Oral Res 2016 Aug 22;30(1):e94. doi: 10.1590/1807-3107BOR-2016.vol30.0094. PMID: 27556681
High resolution ultrasound assessment of the parotid gland.
Howlett DC
Br J Radiol 2003 Apr;76(904):271-7. doi: 10.1259/bjr/33081866. PMID: 12711649

Recent systematic reviews

Salivary gland tissues and derived primary and metastatic neoplasms: unusual pitfalls in the work-up of sellar lesions. A systematic review.
Feola T, Gianno F, De Angelis M, Colonnese C, Esposito V, Giangaspero F, Jaffrain-Rea ML
J Endocrinol Invest 2021 Oct;44(10):2103-2122. Epub 2021 May 3 doi: 10.1007/s40618-021-01577-6. PMID: 33939106Free PMC Article
Peripheral giant cell granuloma associated with dental implants: a systematic review.
Chrcanovic BR, Gomes CC, Gomez RS
J Stomatol Oral Maxillofac Surg 2019 Nov;120(5):456-461. Epub 2019 Jan 21 doi: 10.1016/j.jormas.2019.01.010. PMID: 30677564
Quantifying the outcome of surgical treatment of temporomandibular joint ankylosis: A systematic review and meta-analysis.
De Roo N, Van Doorne L, Troch A, Vermeersch H, Brusselaers N
J Craniomaxillofac Surg 2016 Jan;44(1):6-15. Epub 2015 Sep 10 doi: 10.1016/j.jcms.2015.08.019. PMID: 26433770
Fine-needle aspiration cytology of salivary gland lesions: a systematic review.
Colella G, Cannavale R, Flamminio F, Foschini MP
J Oral Maxillofac Surg 2010 Sep;68(9):2146-53. Epub 2010 Jul 1 doi: 10.1016/j.joms.2009.09.064. PMID: 20580145
Surgical approaches to the submandibular gland: a review of literature.
Beahm DD, Peleaz L, Nuss DW, Schaitkin B, Sedlmayr JC, Rivera-Serrano CM, Zanation AM, Walvekar RR
Int J Surg 2009 Dec;7(6):503-9. Epub 2009 Sep 24 doi: 10.1016/j.ijsu.2009.09.006. PMID: 19782158

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