U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Refractory Mature B-Cell Non-Hodgkin Lymphoma

MedGen UID:
235544
•Concept ID:
C1335726
•
Neoplastic Process
Synonyms: Refractory Mature B-Cell Lymphoma; Refractory Mature B-Cell Neoplasm; Refractory Mature B-Cell Non-Hodgkin's Lymphoma

Definition

Mature B-cell non-Hodgkin lymphoma that does not respond to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Mature B-Cell Non-Hodgkin Lymphoma

Professional guidelines

PubMed

Mantle Cell Lymphoma: the Role of Risk-Adapted Therapy and Treatment of Relapsed Disease.
Tarockoff M, Gonzalez T, Ivanov S, Sandoval-Sus J
Curr Oncol Rep 2022 Oct;24(10):1313-1326. Epub 2022 May 31 doi: 10.1007/s11912-022-01297-x. PMID: 35639332
Hairy cell leukemia 2022: Update on diagnosis, risk-stratification, and treatment.
Troussard X, Maître E, Cornet E
Am J Hematol 2022 Feb 1;97(2):226-236. Epub 2021 Nov 8 doi: 10.1002/ajh.26390. PMID: 34710243
Hairy cell leukemia: 2020 update on diagnosis, risk stratification, and treatment.
Maitre E, Cornet E, Troussard X
Am J Hematol 2019 Dec;94(12):1413-1422. Epub 2019 Oct 31 doi: 10.1002/ajh.25653. PMID: 31591741

Recent clinical studies

Etiology

Immunotherapy with the trifunctional anti-CD20 x anti-CD3 antibody FBTA05 (Lymphomun) in paediatric high-risk patients with recurrent CD20-positive B cell malignancies.
Schuster FR, Stanglmaier M, Woessmann W, Winkler B, Siepermann M, Meisel R, Schlegel PG, Hess J, Lindhofer H, Borkhardt A, Buhmann R
Br J Haematol 2015 Apr;169(1):90-102. Epub 2014 Dec 11 doi: 10.1111/bjh.13242. PMID: 25495919

Diagnosis

Ibrutinib plus RICE or RVICI for relapsed/refractory mature B-cell non-Hodgkin lymphoma in children and young adults: SPARKLE trial.
Burke GAA, Vinti L, Kabickova E, Beishuizen A, Tacyildiz N, Uyttebroeck A, Kang HJ, Luisi F, Minard-Colin V, Burkhardt B, Tamegnon M, Sun S, Curtis M, Deshpande S, Nottage K, Howes A, Srinivasan S, Bhojwani D, Norris R, Cairo M
Blood Adv 2023 Feb 28;7(4):602-610. doi: 10.1182/bloodadvances.2022008802. PMID: 36541957Free PMC Article
Immunotherapy with the trifunctional anti-CD20 x anti-CD3 antibody FBTA05 (Lymphomun) in paediatric high-risk patients with recurrent CD20-positive B cell malignancies.
Schuster FR, Stanglmaier M, Woessmann W, Winkler B, Siepermann M, Meisel R, Schlegel PG, Hess J, Lindhofer H, Borkhardt A, Buhmann R
Br J Haematol 2015 Apr;169(1):90-102. Epub 2014 Dec 11 doi: 10.1111/bjh.13242. PMID: 25495919

Therapy

Ibrutinib plus RICE or RVICI for relapsed/refractory mature B-cell non-Hodgkin lymphoma in children and young adults: SPARKLE trial.
Burke GAA, Vinti L, Kabickova E, Beishuizen A, Tacyildiz N, Uyttebroeck A, Kang HJ, Luisi F, Minard-Colin V, Burkhardt B, Tamegnon M, Sun S, Curtis M, Deshpande S, Nottage K, Howes A, Srinivasan S, Bhojwani D, Norris R, Cairo M
Blood Adv 2023 Feb 28;7(4):602-610. doi: 10.1182/bloodadvances.2022008802. PMID: 36541957Free PMC Article
Immunotherapy with the trifunctional anti-CD20 x anti-CD3 antibody FBTA05 (Lymphomun) in paediatric high-risk patients with recurrent CD20-positive B cell malignancies.
Schuster FR, Stanglmaier M, Woessmann W, Winkler B, Siepermann M, Meisel R, Schlegel PG, Hess J, Lindhofer H, Borkhardt A, Buhmann R
Br J Haematol 2015 Apr;169(1):90-102. Epub 2014 Dec 11 doi: 10.1111/bjh.13242. PMID: 25495919
Outcome of childhood relapsed or refractory mature B-cell non-Hodgkin lymphoma and acute lymphoblastic leukemia.
Anoop P, Sankpal S, Stiller C, Tewari S, Lancaster DL, Khabra K, Taj MM
Leuk Lymphoma 2012 Oct;53(10):1882-8. Epub 2012 Apr 23 doi: 10.3109/10428194.2012.677534. PMID: 22448922

Prognosis

Immunotherapy with the trifunctional anti-CD20 x anti-CD3 antibody FBTA05 (Lymphomun) in paediatric high-risk patients with recurrent CD20-positive B cell malignancies.
Schuster FR, Stanglmaier M, Woessmann W, Winkler B, Siepermann M, Meisel R, Schlegel PG, Hess J, Lindhofer H, Borkhardt A, Buhmann R
Br J Haematol 2015 Apr;169(1):90-102. Epub 2014 Dec 11 doi: 10.1111/bjh.13242. PMID: 25495919
Outcome of childhood relapsed or refractory mature B-cell non-Hodgkin lymphoma and acute lymphoblastic leukemia.
Anoop P, Sankpal S, Stiller C, Tewari S, Lancaster DL, Khabra K, Taj MM
Leuk Lymphoma 2012 Oct;53(10):1882-8. Epub 2012 Apr 23 doi: 10.3109/10428194.2012.677534. PMID: 22448922

Clinical prediction guides

Ibrutinib plus RICE or RVICI for relapsed/refractory mature B-cell non-Hodgkin lymphoma in children and young adults: SPARKLE trial.
Burke GAA, Vinti L, Kabickova E, Beishuizen A, Tacyildiz N, Uyttebroeck A, Kang HJ, Luisi F, Minard-Colin V, Burkhardt B, Tamegnon M, Sun S, Curtis M, Deshpande S, Nottage K, Howes A, Srinivasan S, Bhojwani D, Norris R, Cairo M
Blood Adv 2023 Feb 28;7(4):602-610. doi: 10.1182/bloodadvances.2022008802. PMID: 36541957Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...