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Mediastinal Ganglioneuroma

MedGen UID:
277349
•Concept ID:
C1334654
•
Neoplastic Process
Synonyms: Benign ganglioneuroma of mediastinum; Ganglioneuroma of mediastinum; Ganglioneuroma of Mediastinum; Ganglioneuroma of the Mediastinum
SNOMED CT: Ganglioneuroma of mediastinum (424631008); Benign ganglioneuroma of mediastinum (424631008)

Definition

A ganglioneuroma arising from the mediastinum. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMediastinal Ganglioneuroma

Professional guidelines

PubMed

Dumbbell neurogenic tumors of the mediastinum. Diagnosis and management.
Akwari OE, Payne WS, Onofrio BM, Dines DE, Muhm JR
Mayo Clin Proc 1978 Jun;53(6):353-8. PMID: 651379

Recent clinical studies

Etiology

Imaging Analysis of Ganglioneuroma and Quantitative Analysis of Paraspinal Ganglioneuroma.
Luo L, Zheng X, Tao KZ, Zhang J, Tang YY, Han FG
Med Sci Monit 2019 Jul 15;25:5263-5271. doi: 10.12659/MSM.916792. PMID: 31306406Free PMC Article
Computed tomography and magnetic resonance imaging features of posterior mediastinal ganglioneuroma.
Kato M, Hara M, Ozawa Y, Shimizu S, Shibamoto Y
J Thorac Imaging 2012 Mar;27(2):100-6. doi: 10.1097/RTI.0b013e3181ff6404. PMID: 21263353
Neoplasms associated with pulmonary eosinophilic granuloma.
Tomashefski JF, Khiyami A, Kleinerman J
Arch Pathol Lab Med 1991 May;115(5):499-506. PMID: 2021319

Diagnosis

Total resection of a giant retroperitoneal and mediastinal ganglioneuroma-case report and systematic review of the literature.
Kirchweger P, Wundsam HV, Fischer I, Rösch CS, Böhm G, Tsybrovskyy O, Alibegovic V, Függer R
World J Surg Oncol 2020 Sep 18;18(1):248. doi: 10.1186/s12957-020-02016-1. PMID: 32948207Free PMC Article
Imaging Analysis of Ganglioneuroma and Quantitative Analysis of Paraspinal Ganglioneuroma.
Luo L, Zheng X, Tao KZ, Zhang J, Tang YY, Han FG
Med Sci Monit 2019 Jul 15;25:5263-5271. doi: 10.12659/MSM.916792. PMID: 31306406Free PMC Article
Computed tomography and magnetic resonance imaging features of posterior mediastinal ganglioneuroma.
Kato M, Hara M, Ozawa Y, Shimizu S, Shibamoto Y
J Thorac Imaging 2012 Mar;27(2):100-6. doi: 10.1097/RTI.0b013e3181ff6404. PMID: 21263353
Synchronous mediastinal ganglioneuroma and retroperitoneal pheochromocytoma.
Takeda S, Minami M, Inoue Y, Matsuda H
Ann Thorac Surg 2005 Oct;80(4):1525-7. doi: 10.1016/j.athoracsur.2004.03.065. PMID: 16181913
Posterior mediastinal ganglioneuroma.
Forsythe A, Volpe J, Muller R
Radiographics 2004 Mar-Apr;24(2):594-7. doi: 10.1148/rg.242035077. PMID: 15026603

Therapy

Radiologic findings of thoracic scoliosis due to giant ganglioneuroma.
Kara T, Oztunali C
Clin Imaging 2013 Jul-Aug;37(4):767-8. Epub 2013 Jan 10 doi: 10.1016/j.clinimag.2012.11.003. PMID: 23313187
Neoplasms associated with pulmonary eosinophilic granuloma.
Tomashefski JF, Khiyami A, Kleinerman J
Arch Pathol Lab Med 1991 May;115(5):499-506. PMID: 2021319

Prognosis

Total resection of a giant retroperitoneal and mediastinal ganglioneuroma-case report and systematic review of the literature.
Kirchweger P, Wundsam HV, Fischer I, Rösch CS, Böhm G, Tsybrovskyy O, Alibegovic V, Függer R
World J Surg Oncol 2020 Sep 18;18(1):248. doi: 10.1186/s12957-020-02016-1. PMID: 32948207Free PMC Article
Imaging Analysis of Ganglioneuroma and Quantitative Analysis of Paraspinal Ganglioneuroma.
Luo L, Zheng X, Tao KZ, Zhang J, Tang YY, Han FG
Med Sci Monit 2019 Jul 15;25:5263-5271. doi: 10.12659/MSM.916792. PMID: 31306406Free PMC Article
Neoplasms associated with pulmonary eosinophilic granuloma.
Tomashefski JF, Khiyami A, Kleinerman J
Arch Pathol Lab Med 1991 May;115(5):499-506. PMID: 2021319

Clinical prediction guides

Imaging Analysis of Ganglioneuroma and Quantitative Analysis of Paraspinal Ganglioneuroma.
Luo L, Zheng X, Tao KZ, Zhang J, Tang YY, Han FG
Med Sci Monit 2019 Jul 15;25:5263-5271. doi: 10.12659/MSM.916792. PMID: 31306406Free PMC Article
Posterior mediastinal ganglioneuroma with peripheral replacement by white and brown adipocytes resulting in diagnostic fallacy from a false-positive 18F-2-fluoro-2-deoxyglucose-positron emission tomography finding: a case report.
Yorita K, Yonei A, Ayabe T, Nakada H, Nakashima K, Fukushima T, Kataoka H
J Med Case Rep 2014 Oct 15;8:345. doi: 10.1186/1752-1947-8-345. PMID: 25319096Free PMC Article
Computed tomography and magnetic resonance imaging features of posterior mediastinal ganglioneuroma.
Kato M, Hara M, Ozawa Y, Shimizu S, Shibamoto Y
J Thorac Imaging 2012 Mar;27(2):100-6. doi: 10.1097/RTI.0b013e3181ff6404. PMID: 21263353
Cytoplasmic tubular inclusion in ganglioneuroma.
Matsuda M, Nagashima K
Acta Neuropathol 1984;64(1):81-4. doi: 10.1007/BF00695612. PMID: 6089497
Light and electron microscopic observations on a ganglioneuroma.
Bender BL, Ghatak NR
Acta Neuropathol 1978 Apr 26;42(1):7-10. doi: 10.1007/BF01273259. PMID: 207072

Recent systematic reviews

Total resection of a giant retroperitoneal and mediastinal ganglioneuroma-case report and systematic review of the literature.
Kirchweger P, Wundsam HV, Fischer I, Rösch CS, Böhm G, Tsybrovskyy O, Alibegovic V, Függer R
World J Surg Oncol 2020 Sep 18;18(1):248. doi: 10.1186/s12957-020-02016-1. PMID: 32948207Free PMC Article

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