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Embolism and Thrombosis

MedGen UID:
43147
•Concept ID:
C0085307
•
Disease or Syndrome
Synonym: Thrombosis and Embolism

Definition

A collective term for pathological conditions which are caused by the formation of a blood clot (THROMBUS) in a blood vessel, or by blocking of a blood vessel with an EMBOLUS, undissolved materials in the blood stream. [from MeSH]

Professional guidelines

PubMed

Risk and Management of Bleeding Complications with Direct Oral Anticoagulants in Patients with Atrial Fibrillation and Venous Thromboembolism: a Narrative Review.
Ballestri S, Romagnoli E, Arioli D, Coluccio V, Marrazzo A, Athanasiou A, Di Girolamo M, Cappi C, Marietta M, Capitelli M
Adv Ther 2023 Jan;40(1):41-66. Epub 2022 Oct 16 doi: 10.1007/s12325-022-02333-9. PMID: 36244055Free PMC Article
Endovascular Treatment of Thrombosis and Embolism.
Goktay AY, Senturk C
Adv Exp Med Biol 2017;906:195-213. doi: 10.1007/5584_2016_116. PMID: 27664152
Venous thromboembolism in cancer patients: risk assessment, prevention and management.
Tukaye DN, Brink H, Baliga R
Future Cardiol 2016 Mar;12(2):221-35. Epub 2016 Feb 26 doi: 10.2217/fca.15.87. PMID: 26919091

Recent clinical studies

Etiology

Cerebral microemboli and cognitive impairment.
Russell D
J Neurol Sci 2002 Nov 15;203-204:211-4. doi: 10.1016/s0022-510x(02)00293-9. PMID: 12417386
Thrombolytic therapy.
Brott T
Neurol Clin 1992 Feb;10(1):219-32. PMID: 1557004
Ticlopidine hydrochloride.
Blissitt PA
J Neurosci Nurs 1992 Oct;24(5):296-300. doi: 10.1097/01376517-199210000-00012. PMID: 1402156
Dural sinus and cerebral venous thrombosis.
Nagpal RD
Neurosurg Rev 1983;6(3):155-60. doi: 10.1007/BF01742767. PMID: 6371593
Atrial fibrillation revisited.
Selzer A
N Engl J Med 1982 Apr 29;306(17):1044-5. doi: 10.1056/NEJM198204293061709. PMID: 7062996

Diagnosis

Vertebrobasilar thrombosis: diagnosis, management, and the use of intra-arterial thrombolytics.
Becker KJ, Purcell LL, Hacke W, Hanley DF
Crit Care Med 1996 Oct;24(10):1729-42. doi: 10.1097/00003246-199610000-00022. PMID: 8874314
Locked-in syndrome.
Sepcić J, Sepić-Grahovac D, Strenja-Grubesić J, Antonelli L, Andrasević D
Neurol Croat 1992;41(3):157-61. PMID: 1463800
ATHEROMATOUS EMBOLISM.
ELIOT RS, KANJUH VI, EDWARDS JE
Circulation 1964 Oct;30:611-8. doi: 10.1161/01.cir.30.4.611. PMID: 14211824
OCULAR BOBBING.
FISHER CM
Arch Neurol 1964 Nov;11:543-6. doi: 10.1001/archneur.1964.00460230093008. PMID: 14200662
ENDOCARDITIS.
FRIEDBERG CK
Bull N Y Acad Med 1964 Jul;40(7):522-31. PMID: 14150924Free PMC Article

Therapy

Thrombolytic therapy in peripheral arterial disease.
Giannini D, Balbarini A
Curr Drug Targets Cardiovasc Haematol Disord 2004 Sep;4(3):249-58. doi: 10.2174/1568006043336113. PMID: 15379617
Anticoagulant and defibrinogenating agents in acute ischemic stroke and cerebral venous thrombosis.
Meschia JF
Semin Neurol 1998;18(4):461-70. doi: 10.1055/s-2008-1040899. PMID: 9932617
Prophylaxis and acute therapy of arterial embolism with special reference to cerebral embolism.
Tettenborn B, Krämer G, Erbel R
Herz 1991 Dec;16(6):444-55. PMID: 1765348
Stroke therapy.
Zivin JA, Choi DW
Sci Am 1991 Jul;265(1):56-63. doi: 10.1038/scientificamerican0791-56. PMID: 1679258
Cerebral embolism.
Sherman DG, Dyken ML, Fisher M, Harrison MJ, Hart RG
Chest 1986 Feb;89(2 Suppl):82S-98S. doi: 10.1378/chest.89.2_supplement.82s. PMID: 3510833

Prognosis

Incidence and outcomes of acute mesenteric ischaemia: a systematic review and meta-analysis.
Tamme K, Reintam Blaser A, Laisaar KT, Mändul M, Kals J, Forbes A, Kiss O, Acosta S, Bjørck M, Starkopf J
BMJ Open 2022 Oct 25;12(10):e062846. doi: 10.1136/bmjopen-2022-062846. PMID: 36283747Free PMC Article
Cerebral venous thrombosis.
Ameri A, Bousser MG
Neurol Clin 1992 Feb;10(1):87-111. PMID: 1557011
Fibrinogen and mechanisms of thrombosis. A difficult link.
Di Minno G, Cerbone A, Margaglione M, Vecchione G, Grandone E, Mancini M
Eur J Epidemiol 1992 May;8 Suppl 1:88-91. doi: 10.1007/BF00145357. PMID: 1505658
ENDOCARDITIS.
FRIEDBERG CK
Bull N Y Acad Med 1964 Jul;40(7):522-31. PMID: 14150924Free PMC Article
ANTICOAGULANT THERAPY TODAY.
VIGRAN IM
Angiology 1964 Jan;15:1-10. doi: 10.1177/000331976401500101. PMID: 14106728

Clinical prediction guides

Novel Strategy to Combat the Procoagulant Phenotype in Heparin-Induced Thrombocytopenia Using 12-LOX Inhibition.
Renna SA, Zhao X, Kunapuli SP, Ma P, Holinstat M, Boxer MB, Maloney DJ, Michael JV, McKenzie SE
Arterioscler Thromb Vasc Biol 2023 Oct;43(10):1808-1817. Epub 2023 Jun 22 doi: 10.1161/ATVBAHA.123.319434. PMID: 37345522
Principal Component Analysis on Recurrent Venous Thromboembolism.
Martins TD, Annichino-Bizzacchi JM, Romano AVC, Filho RM
Clin Appl Thromb Hemost 2019 Jan-Dec;25:1076029619895323. doi: 10.1177/1076029619895323. PMID: 31858829Free PMC Article
Brain embolism, revisited.
Caplan LR
Neurology 1993 Jul;43(7):1281-7. doi: 10.1212/wnl.43.7.1281. PMID: 8327124
Fibrinogen and mechanisms of thrombosis. A difficult link.
Di Minno G, Cerbone A, Margaglione M, Vecchione G, Grandone E, Mancini M
Eur J Epidemiol 1992 May;8 Suppl 1:88-91. doi: 10.1007/BF00145357. PMID: 1505658
Locked-in syndrome.
Sepcić J, Sepić-Grahovac D, Strenja-Grubesić J, Antonelli L, Andrasević D
Neurol Croat 1992;41(3):157-61. PMID: 1463800

Recent systematic reviews

Incidence and outcomes of acute mesenteric ischaemia: a systematic review and meta-analysis.
Tamme K, Reintam Blaser A, Laisaar KT, Mändul M, Kals J, Forbes A, Kiss O, Acosta S, Bjørck M, Starkopf J
BMJ Open 2022 Oct 25;12(10):e062846. doi: 10.1136/bmjopen-2022-062846. PMID: 36283747Free PMC Article
Postoperative bleeding and venous thromboembolism in colorectal cancer patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy: a systematic review and meta-analysis.
Lundbech M, Krag AE, Iversen LH, Hvas AM
Int J Colorectal Dis 2022 Jan;37(1):17-33. Epub 2021 Oct 9 doi: 10.1007/s00384-021-04021-6. PMID: 34626208
Thromboembolic Risk of C1 Esterase Inhibitors: A Systematic Review on Current Evidence.
Burnham K, Reinert JP
Expert Rev Clin Pharmacol 2020 Jul;13(7):779-786. Epub 2020 Jun 4 doi: 10.1080/17512433.2020.1776110. PMID: 32476505
Alcohol consumption and the risk of morbidity and mortality for different stroke types--a systematic review and meta-analysis.
Patra J, Taylor B, Irving H, Roerecke M, Baliunas D, Mohapatra S, Rehm J
BMC Public Health 2010 May 18;10:258. doi: 10.1186/1471-2458-10-258. PMID: 20482788Free PMC Article
Correlation between carotid intraplaque hemorrhage and clinical symptoms: systematic review of observational studies.
Gao P, Chen ZQ, Bao YH, Jiao LQ, Ling F
Stroke 2007 Aug;38(8):2382-90. Epub 2007 Jun 28 doi: 10.1161/STROKEAHA.107.482760. PMID: 17600232

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