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Anal Canal Mixed Adenoneuroendocrine Carcinoma

MedGen UID:
474489
•Concept ID:
C3272856
•
Neoplastic Process
Synonyms: Anal Canal MANEC; Anal MANEC; Anal Mixed Adenoneuroendocrine Carcinoma

Definition

A carcinoma that arises from the anal canal. It is characterized by the presence of a malignant glandular epithelial component and a malignant neuroendocrine component. At least 30 percent of either component should be present for the diagnosis to be made. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnal Canal Mixed Adenoneuroendocrine Carcinoma

Recent clinical studies

Diagnosis

Anal canal mixed adenoneuroendocrine carcinoma in a young patient misdiagnosed as anal abscess.
Tutino R, Battistella E, Bonariol L, Massani M
BMJ Case Rep 2021 Sep 21;14(9) doi: 10.1136/bcr-2021-244737. PMID: 34548300Free PMC Article
Oncologic outcome of mixed adenoneuroendocrine carcinoma (MANEC): A single center case series.
Dulskas A, Pilvelis A
Eur J Surg Oncol 2020 Jan;46(1):105-107. Epub 2019 Aug 2 doi: 10.1016/j.ejso.2019.08.002. PMID: 31444026

Prognosis

Oncologic outcome of mixed adenoneuroendocrine carcinoma (MANEC): A single center case series.
Dulskas A, Pilvelis A
Eur J Surg Oncol 2020 Jan;46(1):105-107. Epub 2019 Aug 2 doi: 10.1016/j.ejso.2019.08.002. PMID: 31444026

Clinical prediction guides

Oncologic outcome of mixed adenoneuroendocrine carcinoma (MANEC): A single center case series.
Dulskas A, Pilvelis A
Eur J Surg Oncol 2020 Jan;46(1):105-107. Epub 2019 Aug 2 doi: 10.1016/j.ejso.2019.08.002. PMID: 31444026

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