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Hepatitis, Viral, Human

MedGen UID:
5521
•Concept ID:
C0019195
•
Disease or Syndrome
Synonyms: Human Viral Hepatitides; Human Viral Hepatitis; Viral Hepatitides, Human; Viral Hepatitis, Human

Definition

INFLAMMATION of the LIVER in humans due to infection by VIRUSES. There are several significant types of human viral hepatitis with infection caused by enteric-transmission (HEPATITIS A; HEPATITIS E) or blood transfusion (HEPATITIS B; HEPATITIS C; and HEPATITIS D). [from MeSH]

Professional guidelines

PubMed

Epidemiology and treatment of hepatitis E in the liver transplantation setting: A literature review.
Markakis GE, Papatheodoridis GV, Cholongitas E
J Viral Hepat 2022 Sep;29(9):698-718. Epub 2022 Jun 3 doi: 10.1111/jvh.13709. PMID: 35644040
Hepatitis delta infection - Current and new treatment options.
Elazar M, Koh C, Glenn JS
Best Pract Res Clin Gastroenterol 2017 Jun;31(3):321-327. Epub 2017 May 22 doi: 10.1016/j.bpg.2017.05.001. PMID: 28774414
Emerging concepts for the treatment of hepatitis delta.
Elazar M, Glenn JS
Curr Opin Virol 2017 Jun;24:55-59. Epub 2017 May 2 doi: 10.1016/j.coviro.2017.04.004. PMID: 28475945

Recent clinical studies

Etiology

Present and future management of viral hepatitis.
González Grande R, Santaella Leiva I, López Ortega S, Jiménez Pérez M
World J Gastroenterol 2021 Dec 21;27(47):8081-8102. doi: 10.3748/wjg.v27.i47.8081. PMID: 35068856Free PMC Article
Chronic Viral Hepatitis and Metabolic Syndrome/Cardiovascular Risk.
Jarcuska P, Abdel-Razik A, Flisiak R, Singh RB
Can J Gastroenterol Hepatol 2018;2018:7369314. Epub 2018 Nov 4 doi: 10.1155/2018/7369314. PMID: 30519548Free PMC Article
Hepatitis Viruses in Kidney Transplantation.
Gajurel K, Stapleton JT
Semin Nephrol 2016 Sep;36(5):386-396. doi: 10.1016/j.semnephrol.2016.05.015. PMID: 27772623
The Willowbrook hepatitis studies revisited: ethical aspects.
Krugman S
Rev Infect Dis 1986 Jan-Feb;8(1):157-62. doi: 10.1093/clinids/8.1.157. PMID: 3952423
Viral hepatitis.
Gitnick GL
West J Med 1978 Feb;128(2):117-26. PMID: 629050Free PMC Article

Diagnosis

From hepatitis A to E: A critical review of viral hepatitis.
Castaneda D, Gonzalez AJ, Alomari M, Tandon K, Zervos XB
World J Gastroenterol 2021 Apr 28;27(16):1691-1715. doi: 10.3748/wjg.v27.i16.1691. PMID: 33967551Free PMC Article
Epstein-Barr Virus and Cytomegalovirus Infections of the Liver.
Bunchorntavakul C, Reddy KR
Gastroenterol Clin North Am 2020 Jun;49(2):331-346. doi: 10.1016/j.gtc.2020.01.008. PMID: 32389366
Viral hepatitis.
Hardikar W
J Paediatr Child Health 2019 Sep;55(9):1038-1043. Epub 2019 Jul 17 doi: 10.1111/jpc.14562. PMID: 31317618
Epstein-Barr Virus Hepatitis: A Review of Clinicopathologic Features and Differential Diagnosis.
Schechter S, Lamps L
Arch Pathol Lab Med 2018 Oct;142(10):1191-1195. doi: 10.5858/arpa.2018-0208-RA. PMID: 30281361
Viral hepatitis.
Gregorio GV, Mieli-Vergani G, Mowat AP
Arch Dis Child 1994 Apr;70(4):343-8. doi: 10.1136/adc.70.4.343. PMID: 8185372Free PMC Article

Therapy

Infectious Hepatitis in Pregnancy.
Hamburg-Shields E, Prasad M
Clin Obstet Gynecol 2020 Mar;63(1):175-192. doi: 10.1097/GRF.0000000000000512. PMID: 31895116
Viral Hepatitis and Acute Liver Failure: Still a Problem.
Sedhom D, D'Souza M, John E, Rustgi V
Clin Liver Dis 2018 May;22(2):289-300. doi: 10.1016/j.cld.2018.01.005. PMID: 29605067
Update on viral hepatitis in pregnancy.
Shao Z, Al Tibi M, Wakim-Fleming J
Cleve Clin J Med 2017 Mar;84(3):202-206. doi: 10.3949/ccjm.84a.15139. PMID: 28322675
Viral Hepatitis in Children: A Through E.
Chugh A, Maximos M, Perlman M, Gonzalez-Peralta RP
Pediatr Ann 2016 Dec 1;45(12):e420-e426. doi: 10.3928/19382359-20161114-01. PMID: 27975110
Hepatitis Viruses in Kidney Transplantation.
Gajurel K, Stapleton JT
Semin Nephrol 2016 Sep;36(5):386-396. doi: 10.1016/j.semnephrol.2016.05.015. PMID: 27772623

Prognosis

Viral hepatitis in haemophilia: historical perspective and current management.
Isfordink CJ, van Erpecum KJ, van der Valk M, Mauser-Bunschoten EP, Makris M
Br J Haematol 2021 Oct;195(2):174-185. Epub 2021 May 6 doi: 10.1111/bjh.17438. PMID: 33955555
Viral hepatitis and pregnancy.
Terrault NA, Levy MT, Cheung KW, Jourdain G
Nat Rev Gastroenterol Hepatol 2021 Feb;18(2):117-130. Epub 2020 Oct 12 doi: 10.1038/s41575-020-00361-w. PMID: 33046891
Viral Hepatitis and Acute Liver Failure: Still a Problem.
Sedhom D, D'Souza M, John E, Rustgi V
Clin Liver Dis 2018 May;22(2):289-300. doi: 10.1016/j.cld.2018.01.005. PMID: 29605067
Viral Hepatitis in Children: A Through E.
Chugh A, Maximos M, Perlman M, Gonzalez-Peralta RP
Pediatr Ann 2016 Dec 1;45(12):e420-e426. doi: 10.3928/19382359-20161114-01. PMID: 27975110
Acute liver failure.
Bernal W, Auzinger G, Dhawan A, Wendon J
Lancet 2010 Jul 17;376(9736):190-201. doi: 10.1016/S0140-6736(10)60274-7. PMID: 20638564

Clinical prediction guides

T and NK Cell-Based Immunotherapy in Chronic Viral Hepatitis and Hepatocellular Carcinoma.
Fisicaro P, Boni C
Cells 2022 Jan 6;11(2) doi: 10.3390/cells11020180. PMID: 35053296Free PMC Article
Acute-on-chronic liver failure: an update.
Hernaez R, Solà E, Moreau R, Ginès P
Gut 2017 Mar;66(3):541-553. Epub 2017 Jan 4 doi: 10.1136/gutjnl-2016-312670. PMID: 28053053Free PMC Article
Prediction of fibrosis progression in chronic viral hepatitis.
Wong GL
Clin Mol Hepatol 2014 Sep;20(3):228-36. Epub 2014 Sep 25 doi: 10.3350/cmh.2014.20.3.228. PMID: 25320725Free PMC Article
Virus hepatitis update.
Summerfield JA
J R Coll Physicians Lond 2000 Jul-Aug;34(4):381-5. PMID: 11005078Free PMC Article
Hepatitis testing.
Bianco C
Immunol Invest 1995 Jan-Feb;24(1-2):155-61. doi: 10.3109/08820139509062769. PMID: 7713579

Recent systematic reviews

Machine learning for prediction of viral hepatitis: A systematic review and meta-analysis.
Moulaei K, Sharifi H, Bahaadinbeigy K, Haghdoost AA, Nasiri N
Int J Med Inform 2023 Nov;179:105243. Epub 2023 Oct 4 doi: 10.1016/j.ijmedinf.2023.105243. PMID: 37806178
Worldwide prevalence of hepatitis B virus and hepatitis C virus among patients with cirrhosis at country, region, and global levels: a systematic review.
Alberts CJ, Clifford GM, Georges D, Negro F, Lesi OA, Hutin YJ, de Martel C
Lancet Gastroenterol Hepatol 2022 Aug;7(8):724-735. Epub 2022 May 14 doi: 10.1016/S2468-1253(22)00050-4. PMID: 35576953Free PMC Article
Epidemiology of viral hepatitis in Somalia: Systematic review and meta-analysis study.
Hassan-Kadle MA, Osman MS, Ogurtsov PP
World J Gastroenterol 2018 Sep 14;24(34):3927-3957. doi: 10.3748/wjg.v24.i34.3927. PMID: 30228786Free PMC Article
Comorbidity of viral hepatitis and chronic spontaneous urticaria: A systematic review.
Kolkhir P, Pereverzina N, Olisova O, Maurer M
Allergy 2018 Oct;73(10):1946-1953. Epub 2018 Jun 12 doi: 10.1111/all.13482. PMID: 29786879
Silymarin treatment of viral hepatitis: a systematic review.
Mayer KE, Myers RP, Lee SS
J Viral Hepat 2005 Nov;12(6):559-67. doi: 10.1111/j.1365-2893.2005.00636.x. PMID: 16255756

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