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Lacrimal duct cancer

MedGen UID:
57795
•Concept ID:
C0153631
•
Neoplastic Process
Synonyms: cancer of lacrimal drainage system; lacrimal drainage system cancer; lacrimal duct cancer; malignant lacrimal drainage system neoplasm; Malignant Lacrimal Duct Neoplasm; malignant lacrimal duct neoplasm; Malignant Lacrimal Duct Tumor; malignant lacrimal duct tumor; malignant lacrimal duct tumour; Malignant Nasolacrimal Duct Neoplasm; malignant neoplasm of lacrimal drainage system; Malignant Neoplasm of Lacrimal Duct; Malignant neoplasm of lacrimal duct; malignant neoplasm of lacrimal duct; Malignant Neoplasm of the Lacrimal Duct; malignant neoplasm of the lacrimal duct; Malignant Tumor of Lacrimal Duct; malignant tumor of lacrimal duct; Malignant Tumor of the Lacrimal Duct; malignant tumor of the lacrimal duct; malignant tumour of lacrimal duct; malignant tumour of the lacrimal duct
SNOMED CT: Malignant neoplasm of lacrimal duct (188274004)
 
Monarch Initiative: MONDO:0001580

Definition

A primary or metastatic malignant neoplasm affecting the lacrimal duct. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLacrimal duct cancer

Professional guidelines

PubMed

Clinical management and outcomes of lacrimal sac squamous cell carcinoma.
Song X, Wang S, Wang J, Wang W, Wang S, Yang G, Li J, Zhu Y, Chen F, Zhu W
Head Neck 2019 Apr;41(4):974-981. Epub 2019 Jan 10 doi: 10.1002/hed.25529. PMID: 30629760
Clinical features and management of dacryops.
Ozgonul C, Uysal Y, Ayyildiz O, Kucukevcilioglu M
Orbit 2018 Aug;37(4):262-265. Epub 2018 Jan 4 doi: 10.1080/01676830.2017.1423081. PMID: 29300516
Current treatment of lacrimal gland carcinoma.
Woo KI, Kim YD, Sa HS, Esmaeli B
Curr Opin Ophthalmol 2016 Sep;27(5):449-56. doi: 10.1097/ICU.0000000000000301. PMID: 27273588

Recent clinical studies

Etiology

Blood-stained tears-a red flag for malignancy?
Kaushik M, Juniat V, Ezra DG, Verity DH, Uddin J, Timlin H
Eye (Lond) 2023 Jun;37(8):1711-1716. Epub 2022 Sep 10 doi: 10.1038/s41433-022-02224-x. PMID: 36088421Free PMC Article
Human Papillomavirus Related Neoplasia of the Ocular Adnexa.
Ramberg I, Heegaard S
Viruses 2021 Aug 2;13(8) doi: 10.3390/v13081522. PMID: 34452388Free PMC Article
Carcinomas of the lacrimal drainage system.
Ramberg I, Toft PB, Heegaard S
Surv Ophthalmol 2020 Nov-Dec;65(6):691-707. Epub 2020 Apr 15 doi: 10.1016/j.survophthal.2020.04.001. PMID: 32304675
Overview of benign and malignant lacrimal gland tumors.
Gündüz AK, Yeşiltaş YS, Shields CL
Curr Opin Ophthalmol 2018 Sep;29(5):458-468. doi: 10.1097/ICU.0000000000000515. PMID: 30028745
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337

Diagnosis

Carcinomas of the lacrimal drainage system.
Ramberg I, Toft PB, Heegaard S
Surv Ophthalmol 2020 Nov-Dec;65(6):691-707. Epub 2020 Apr 15 doi: 10.1016/j.survophthal.2020.04.001. PMID: 32304675
Congenital Dacryocystocele: A Major Review.
Singh S, Ali MJ
Ophthalmic Plast Reconstr Surg 2019 Jul/Aug;35(4):309-317. doi: 10.1097/IOP.0000000000001297. PMID: 30601463
IgG4-related orbital disease.
Flores Balverdi J, Baenas DF, Riscanevo NC, Sánchez AV, Figueroa Rosales R, Alvarellos A
Arch Soc Esp Oftalmol (Engl Ed) 2018 Oct;93(10):494-496. Epub 2018 Jun 1 doi: 10.1016/j.oftal.2018.04.003. PMID: 29866378
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337
Tumors of the lacrimal gland.
von Holstein SL, Rasmussen PK, Heegaard S
Semin Diagn Pathol 2016 May;33(3):156-63. Epub 2015 Oct 9 doi: 10.1053/j.semdp.2015.10.002. PMID: 26849904

Therapy

Dysfunction of the Salivary and Lacrimal Glands After Radioiodine Therapy for Thyroid Cancer: Results of the START Study After 6-Months of Follow-Up.
Baudin C, Bressand A, Buffet C, Menegaux F, Soret M, Lê AT, Cardon T, Broggio D, Bassinet C, Huet C, Armengol G, Richardson DB, Leenhardt L, Bernier MO, Lussey-Lepoutre C
Thyroid 2023 Sep;33(9):1100-1109. Epub 2023 Jun 23 doi: 10.1089/thy.2023.0090. PMID: 37300484
Lymphoproliferative tumors involving the lacrimal drainage system: a major review.
Singh S, Ali MJ
Orbit 2020 Aug;39(4):276-284. Epub 2019 Jul 3 doi: 10.1080/01676830.2019.1634104. PMID: 31267826
Evaluation and Management of Chemotherapy-Induced Epiphora, Punctal and Canalicular Stenosis, and Nasolacrimal Duct Obstruction.
Mansur C, Pfeiffer ML, Esmaeli B
Ophthalmic Plast Reconstr Surg 2017 Jan/Feb;33(1):9-12. doi: 10.1097/IOP.0000000000000745. PMID: 27429222
Mycotic Infections of the Eye.
Słowik M, Biernat MM, Urbaniak-Kujda D, Kapelko-Słowik K, Misiuk-Hojło M
Adv Clin Exp Med 2015 Nov-Dec;24(6):1113-7. doi: 10.17219/acem/50572. PMID: 26771986
Docetaxel-associated epiphora.
Kintzel PE, Michaud LB, Lange MK
Pharmacotherapy 2006 Jun;26(6):853-67. doi: 10.1592/phco.26.6.853. PMID: 16716138

Prognosis

Gene Fusions in Ocular Adnexal Tumors.
Milman T, Ida CM, Zhang PJL, Eagle RC Jr
Am J Ophthalmol 2021 Jan;221:211-225. Epub 2020 Aug 13 doi: 10.1016/j.ajo.2020.08.012. PMID: 32800827
Lymphoproliferative Tumors of the Ocular Adnexa.
Verdijk RM
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):132-142. doi: 10.22608/APO.2016209. PMID: 28399341
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337
An Update on Tumors of the Lacrimal Gland.
Andreasen S, Esmaeli B, Holstein SL, Mikkelsen LH, Rasmussen PK, Heegaard S
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):159-172. doi: 10.22608/APO.201707. PMID: 28399336
Tumors of the lacrimal gland.
von Holstein SL, Rasmussen PK, Heegaard S
Semin Diagn Pathol 2016 May;33(3):156-63. Epub 2015 Oct 9 doi: 10.1053/j.semdp.2015.10.002. PMID: 26849904

Clinical prediction guides

Dacryops and clinical diagnostic challenges.
Alsarhani WK, Al-Sharif EM, Al-Faky YH, Alkatan HM, Maktabi AM, Alsuhaibani AH
Can J Ophthalmol 2022 Dec;57(6):388-393. Epub 2021 Jul 26 doi: 10.1016/j.jcjo.2021.06.014. PMID: 34324876
Human Papillomavirus Related Neoplasia of the Ocular Adnexa.
Ramberg I, Heegaard S
Viruses 2021 Aug 2;13(8) doi: 10.3390/v13081522. PMID: 34452388Free PMC Article
Dacryops - A review.
Tanaboonyawat S, Idowu OO, Copperman TS, Vagefi MR, Kersten RC
Orbit 2020 Apr;39(2):128-134. Epub 2019 Sep 12 doi: 10.1080/01676830.2019.1608564. PMID: 31512543
IgG4-related orbital disease.
Flores Balverdi J, Baenas DF, Riscanevo NC, Sánchez AV, Figueroa Rosales R, Alvarellos A
Arch Soc Esp Oftalmol (Engl Ed) 2018 Oct;93(10):494-496. Epub 2018 Jun 1 doi: 10.1016/j.oftal.2018.04.003. PMID: 29866378
Mycotic Infections of the Eye.
Słowik M, Biernat MM, Urbaniak-Kujda D, Kapelko-Słowik K, Misiuk-Hojło M
Adv Clin Exp Med 2015 Nov-Dec;24(6):1113-7. doi: 10.17219/acem/50572. PMID: 26771986

Recent systematic reviews

Holding back the tears: is there a role for marsupialisation?
Chiu SJ, Currie ZI, Tan JH
BMJ Open Ophthalmol 2022 Aug;7(1) doi: 10.1136/bmjophth-2022-000985. PMID: 36161857Free PMC Article
Ectopic Lacrimal Gland Tissue: A Systematic Review.
Nagendran S, Alsamnan M, Strianese D, Malhotra R
Ophthalmic Plast Reconstr Surg 2020 Nov/Dec;36(6):540-544. doi: 10.1097/IOP.0000000000001621. PMID: 32205779
A systematic review of sinonasal oncocytomas and oncocytic carcinomas: Diagnosis, management, and technical considerations.
Hodzic Z, Rowan NR, Kashiwazaki R, Willson TJ, Wang EW, Lee SE
Int Forum Allergy Rhinol 2017 May;7(5):514-524. Epub 2017 Jan 16 doi: 10.1002/alr.21902. PMID: 28092140
IgG4-related skin disease may have distinct systemic manifestations: a systematic review.
Bennett AE, Fenske NA, Rodriguez-Waitkus P, Messina JL
Int J Dermatol 2016 Nov;55(11):1184-1195. doi: 10.1111/ijd.13369. PMID: 27419384
Nasolacrimal duct tumours in the era of endoscopic dacryocystorhinostomy: literature review.
Tanweer F, Mahkamova K, Harkness P
J Laryngol Otol 2013 Jul;127(7):670-5. Epub 2013 Jun 12 doi: 10.1017/S0022215113001163. PMID: 23756574

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