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Disease due to Flavivirus

MedGen UID:
61641
•Concept ID:
C0206608
•
Disease or Syndrome
Synonyms: Flavivirus Infection; Flavivirus Infections; Infection, Flavivirus; Infections, Flavivirus
SNOMED CT: Disease due to Flavivirus (111865007); Disease caused by Flavivirus (111865007)

Definition

Infections with viruses of the genus FLAVIVIRUS, family FLAVIVIRIDAE. [from MeSH]

Professional guidelines

PubMed

Management of Dengue: An Updated Review.
Tayal A, Kabra SK, Lodha R
Indian J Pediatr 2023 Feb;90(2):168-177. Epub 2022 Dec 27 doi: 10.1007/s12098-022-04394-8. PMID: 36574088Free PMC Article
Dengue infection: Global importance, immunopathology and management.
Kularatne SA, Dalugama C
Clin Med (Lond) 2022 Jan;22(1):9-13. doi: 10.7861/clinmed.2021-0791. PMID: 35078789Free PMC Article
Diagnosis and management of Guillain-Barré syndrome in ten steps.
Leonhard SE, Mandarakas MR, Gondim FAA, Bateman K, Ferreira MLB, Cornblath DR, van Doorn PA, Dourado ME, Hughes RAC, Islam B, Kusunoki S, Pardo CA, Reisin R, Sejvar JJ, Shahrizaila N, Soares C, Umapathi T, Wang Y, Yiu EM, Willison HJ, Jacobs BC
Nat Rev Neurol 2019 Nov;15(11):671-683. Epub 2019 Sep 20 doi: 10.1038/s41582-019-0250-9. PMID: 31541214Free PMC Article

Recent clinical studies

Etiology

Dengue, chikungunya and zika arbovirus infections in Caribbean children.
Christie CDC, Lue AM, Melbourne-Chambers RH
Curr Opin Pediatr 2023 Apr 1;35(2):155-165. Epub 2023 Feb 22 doi: 10.1097/MOP.0000000000001229. PMID: 36801979Free PMC Article
Zika virus-spread, epidemiology, genome, transmission cycle, clinical manifestation, associated challenges, vaccine and antiviral drug development.
Pielnaa P, Al-Saadawe M, Saro A, Dama MF, Zhou M, Huang Y, Huang J, Xia Z
Virology 2020 Apr;543:34-42. Epub 2020 Feb 2 doi: 10.1016/j.virol.2020.01.015. PMID: 32056845
Recent advances in understanding dengue.
Halstead S
F1000Res 2019;8 Epub 2019 Jul 31 doi: 10.12688/f1000research.19197.1. PMID: 31448083Free PMC Article
Dengue in children.
Verhagen LM, de Groot R
J Infect 2014 Nov;69 Suppl 1:S77-86. Epub 2014 Sep 13 doi: 10.1016/j.jinf.2014.07.020. PMID: 25225163
Japanese encephalitis: the virus and vaccines.
Yun SI, Lee YM
Hum Vaccin Immunother 2014;10(2):263-79. Epub 2013 Oct 25 doi: 10.4161/hv.26902. PMID: 24161909Free PMC Article

Diagnosis

Dengue infection: Global importance, immunopathology and management.
Kularatne SA, Dalugama C
Clin Med (Lond) 2022 Jan;22(1):9-13. doi: 10.7861/clinmed.2021-0791. PMID: 35078789Free PMC Article
Zika virus-spread, epidemiology, genome, transmission cycle, clinical manifestation, associated challenges, vaccine and antiviral drug development.
Pielnaa P, Al-Saadawe M, Saro A, Dama MF, Zhou M, Huang Y, Huang J, Xia Z
Virology 2020 Apr;543:34-42. Epub 2020 Feb 2 doi: 10.1016/j.virol.2020.01.015. PMID: 32056845
Zika Virus.
Musso D, Gubler DJ
Clin Microbiol Rev 2016 Jul;29(3):487-524. doi: 10.1128/CMR.00072-15. PMID: 27029595Free PMC Article
Dengue in children.
Verhagen LM, de Groot R
J Infect 2014 Nov;69 Suppl 1:S77-86. Epub 2014 Sep 13 doi: 10.1016/j.jinf.2014.07.020. PMID: 25225163
Tick-borne encephalitis.
Lindquist L, Vapalahti O
Lancet 2008 May 31;371(9627):1861-71. doi: 10.1016/S0140-6736(08)60800-4. PMID: 18514730

Therapy

Management of Dengue: An Updated Review.
Tayal A, Kabra SK, Lodha R
Indian J Pediatr 2023 Feb;90(2):168-177. Epub 2022 Dec 27 doi: 10.1007/s12098-022-04394-8. PMID: 36574088Free PMC Article
Three-year Efficacy and Safety of Takeda's Dengue Vaccine Candidate (TAK-003).
Rivera L, Biswal S, Sáez-Llorens X, Reynales H, López-Medina E, Borja-Tabora C, Bravo L, Sirivichayakul C, Kosalaraksa P, Martinez Vargas L, Yu D, Watanaveeradej V, Espinoza F, Dietze R, Fernando L, Wickramasinghe P, Duarte MoreiraJr E, Fernando AD, Gunasekera D, Luz K, Venâncioda Cunha R, Rauscher M, Zent O, Liu M, Hoffman E, LeFevre I, Tricou V, Wallace D, Alera M, Borkowski A
Clin Infect Dis 2022 Aug 24;75(1):107-117. doi: 10.1093/cid/ciab864. PMID: 34606595Free PMC Article
Zika virus-spread, epidemiology, genome, transmission cycle, clinical manifestation, associated challenges, vaccine and antiviral drug development.
Pielnaa P, Al-Saadawe M, Saro A, Dama MF, Zhou M, Huang Y, Huang J, Xia Z
Virology 2020 Apr;543:34-42. Epub 2020 Feb 2 doi: 10.1016/j.virol.2020.01.015. PMID: 32056845
Dengue Fever: Causes, Complications, and Vaccine Strategies.
Khetarpal N, Khanna I
J Immunol Res 2016;2016:6803098. Epub 2016 Jul 20 doi: 10.1155/2016/6803098. PMID: 27525287Free PMC Article
Dengue and dengue hemorrhagic fever.
Gubler DJ
Clin Microbiol Rev 1998 Jul;11(3):480-96. doi: 10.1128/CMR.11.3.480. PMID: 9665979Free PMC Article

Prognosis

Concurrent dengue infections: Epidemiology & clinical implications.
N Sirisena PDN, Mahilkar S, Sharma C, Jain J, Sunil S
Indian J Med Res 2021 May;154(5):669-679. doi: 10.4103/ijmr.IJMR_1219_18. PMID: 35532585Free PMC Article
Pathobiology of Japanese encephalitis virus infection.
Sharma KB, Vrati S, Kalia M
Mol Aspects Med 2021 Oct;81:100994. Epub 2021 Jul 15 doi: 10.1016/j.mam.2021.100994. PMID: 34274157
The global economic burden of dengue: a systematic analysis.
Shepard DS, Undurraga EA, Halasa YA, Stanaway JD
Lancet Infect Dis 2016 Aug;16(8):935-41. Epub 2016 Apr 16 doi: 10.1016/S1473-3099(16)00146-8. PMID: 27091092
Yellow fever.
Monath TP, Vasconcelos PF
J Clin Virol 2015 Mar;64:160-73. Epub 2014 Oct 24 doi: 10.1016/j.jcv.2014.08.030. PMID: 25453327
Dengue and dengue hemorrhagic fever.
Gubler DJ
Clin Microbiol Rev 1998 Jul;11(3):480-96. doi: 10.1128/CMR.11.3.480. PMID: 9665979Free PMC Article

Clinical prediction guides

Dengue, chikungunya and zika arbovirus infections in Caribbean children.
Christie CDC, Lue AM, Melbourne-Chambers RH
Curr Opin Pediatr 2023 Apr 1;35(2):155-165. Epub 2023 Feb 22 doi: 10.1097/MOP.0000000000001229. PMID: 36801979Free PMC Article
Predictors of severe dengue amongst children as per the revised WHO classification.
Arora SK, Nandan D, Sharma A, Benerjee P, Singh DP
J Vector Borne Dis 2021 Oct-Dec;58(4):329-334. doi: 10.4103/0972-9062.318312. PMID: 35381822
Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction.
Biering SB, Akey DL, Wong MP, Brown WC, Lo NTN, Puerta-Guardo H, Tramontini Gomes de Sousa F, Wang C, Konwerski JR, Espinosa DA, Bockhaus NJ, Glasner DR, Li J, Blanc SF, Juan EY, Elledge SJ, Mina MJ, Beatty PR, Smith JL, Harris E
Science 2021 Jan 8;371(6525):194-200. doi: 10.1126/science.abc0476. PMID: 33414220Free PMC Article
Current Understanding of the Pathogenesis of Dengue Virus Infection.
Bhatt P, Sabeena SP, Varma M, Arunkumar G
Curr Microbiol 2021 Jan;78(1):17-32. Epub 2020 Nov 24 doi: 10.1007/s00284-020-02284-w. PMID: 33231723Free PMC Article
Recent advances in understanding dengue.
Halstead S
F1000Res 2019;8 Epub 2019 Jul 31 doi: 10.12688/f1000research.19197.1. PMID: 31448083Free PMC Article

Recent systematic reviews

Dengue overview: An updated systemic review.
Khan MB, Yang ZS, Lin CY, Hsu MC, Urbina AN, Assavalapsakul W, Wang WH, Chen YH, Wang SF
J Infect Public Health 2023 Oct;16(10):1625-1642. Epub 2023 Aug 3 doi: 10.1016/j.jiph.2023.08.001. PMID: 37595484
Epidemiology and costs of dengue in Brazil: a systematic literature review.
Junior JBS, Massad E, Lobao-Neto A, Kastner R, Oliver L, Gallagher E
Int J Infect Dis 2022 Sep;122:521-528. Epub 2022 Jul 3 doi: 10.1016/j.ijid.2022.06.050. PMID: 35793756
Clinical predictors of severe dengue: a systematic review and meta-analysis.
Tsheten T, Clements ACA, Gray DJ, Adhikary RK, Furuya-Kanamori L, Wangdi K
Infect Dis Poverty 2021 Oct 9;10(1):123. doi: 10.1186/s40249-021-00908-2. PMID: 34627388Free PMC Article
Dengue and the heart.
Araiza-Garaygordobil D, García-Martínez CE, Burgos LM, Saldarriaga C, Liblik K, Mendoza I, Martinez-Selles M, Scatularo CE, Farina JM, Baranchuk A; Neglected Tropical Diseases and other Infectious Diseases affecting the Heart (the NET‐Heart) project
Cardiovasc J Afr 2021 Sep-Oct 23;32(5):276-283. Epub 2021 Jul 20 doi: 10.5830/CVJA-2021-033. PMID: 34292294Free PMC Article
Dengue hemorrhagic fever - A systemic literature review of current perspectives on pathogenesis, prevention and control.
Wang WH, Urbina AN, Chang MR, Assavalapsakul W, Lu PL, Chen YH, Wang SF
J Microbiol Immunol Infect 2020 Dec;53(6):963-978. Epub 2020 Mar 26 doi: 10.1016/j.jmii.2020.03.007. PMID: 32265181

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