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Neoplasm of the larynx

MedGen UID:
7271
•Concept ID:
C0023055
•
Neoplastic Process
Synonyms: Laryngeal Neoplasm; Laryngeal Neoplasms; Larynx Neoplasm; Larynx Neoplasms; Neoplasm, Laryngeal; Neoplasm, Larynx; Neoplasms, Laryngeal; Neoplasms, Larynx
SNOMED CT: Neoplasm of larynx (126692004); Tumor of larynx (126692004)
 
HPO: HP:0100605
Monarch Initiative: MONDO:0021071

Definition

A benign or malignant neoplasm involving the larynx. [from NCI]

Professional guidelines

PubMed

High-throughput screening identifies candidate drugs for the treatment of recurrent respiratory papillomatosis.
Alkhilaiwi F, Paul S, Zhou D, Zhang X, Wang F, Palechor-Ceron N, Wilson K, Guha R, Ferrer M, Grant N, Thomas C, Schlegel R, Yuan H
Papillomavirus Res 2019 Dec;8:100181. Epub 2019 Aug 22 doi: 10.1016/j.pvr.2019.100181. PMID: 31446060Free PMC Article
Treatment of paediatric laryngeal papillomas: web survey of British Association of Paediatric Otolaryngologists.
Manickavasagam J, Wu K, Bateman ND
J Laryngol Otol 2013 Sep;127(9):917-21. Epub 2013 Aug 8 doi: 10.1017/S0022215113001588. PMID: 23927772
Cidofovir for the treatment of recurrent respiratory papillomatosis: a review of the literature.
Shehab N, Sweet BV, Hogikyan ND
Pharmacotherapy 2005 Jul;25(7):977-89. doi: 10.1592/phco.2005.25.7.977. PMID: 16006276

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Head and Neck Cancers, 2024

Recent clinical studies

Etiology

Juvenile-onset recurrent respiratory papillomatosis.
Maturo SC, Hartnick CJ
Adv Otorhinolaryngol 2012;73:105-8. Epub 2012 Mar 29 doi: 10.1159/000334457. PMID: 22472239
Laryngeal solitary fibrous tumour.
Stomeo F, Padovani D, Bozzo C, Pastore A
Auris Nasus Larynx 2007 Sep;34(3):405-8. Epub 2007 Mar 6 doi: 10.1016/j.anl.2007.01.001. PMID: 17337142
Cidofovir for the treatment of recurrent respiratory papillomatosis: a review of the literature.
Shehab N, Sweet BV, Hogikyan ND
Pharmacotherapy 2005 Jul;25(7):977-89. doi: 10.1592/phco.2005.25.7.977. PMID: 16006276
Chondrosarcoma of the larynx: challenges in diagnosis and management.
Bogdan CJ, Maniglia AJ, Eliachar I, Katz RL
Head Neck 1994 Mar-Apr;16(2):127-34. doi: 10.1002/hed.2880160205. PMID: 8021131
Spindle cell carcinoma of the larynx.
Hyams VJ
Can J Otolaryngol 1975;4(2):307-13. PMID: 1139427

Diagnosis

Juvenile-onset recurrent respiratory papillomatosis.
Maturo SC, Hartnick CJ
Adv Otorhinolaryngol 2012;73:105-8. Epub 2012 Mar 29 doi: 10.1159/000334457. PMID: 22472239
Recurrent respiratory papillomatosis: a review.
Derkay CS, Wiatrak B
Laryngoscope 2008 Jul;118(7):1236-47. doi: 10.1097/MLG.0b013e31816a7135. PMID: 18496162
Laryngeal solitary fibrous tumour.
Stomeo F, Padovani D, Bozzo C, Pastore A
Auris Nasus Larynx 2007 Sep;34(3):405-8. Epub 2007 Mar 6 doi: 10.1016/j.anl.2007.01.001. PMID: 17337142
Diagnostic procedures for detection of lymph node metastases in cancer of the larynx.
Kau RJ, Alexiou C, Stimmer H, Arnold W
ORL J Otorhinolaryngol Relat Spec 2000 Jul-Aug;62(4):199-203. doi: 10.1159/000027746. PMID: 10859520
Chondrosarcoma of the larynx: challenges in diagnosis and management.
Bogdan CJ, Maniglia AJ, Eliachar I, Katz RL
Head Neck 1994 Mar-Apr;16(2):127-34. doi: 10.1002/hed.2880160205. PMID: 8021131

Therapy

Systemic bevacizumab as adjuvant therapy for recurrent respiratory papillomatosis in children: A series of three pediatric cases and literature review.
Enrique OH, Eloy SH, Adrian TP, Perla V
Am J Otolaryngol 2021 Sep-Oct;42(5):103126. Epub 2021 Jun 24 doi: 10.1016/j.amjoto.2021.103126. PMID: 34175693
Relationships among smoking, organic, and functional voice disorders in Korean general population.
Byeon H
J Voice 2015 May;29(3):312-6. Epub 2014 Dec 12 doi: 10.1016/j.jvoice.2014.07.015. PMID: 25510162
Treatment of paediatric laryngeal papillomas: web survey of British Association of Paediatric Otolaryngologists.
Manickavasagam J, Wu K, Bateman ND
J Laryngol Otol 2013 Sep;127(9):917-21. Epub 2013 Aug 8 doi: 10.1017/S0022215113001588. PMID: 23927772
Juvenile-onset recurrent respiratory papillomatosis.
Maturo SC, Hartnick CJ
Adv Otorhinolaryngol 2012;73:105-8. Epub 2012 Mar 29 doi: 10.1159/000334457. PMID: 22472239
Cidofovir for the treatment of recurrent respiratory papillomatosis: a review of the literature.
Shehab N, Sweet BV, Hogikyan ND
Pharmacotherapy 2005 Jul;25(7):977-89. doi: 10.1592/phco.2005.25.7.977. PMID: 16006276

Prognosis

Juvenile-onset recurrent respiratory papillomatosis.
Maturo SC, Hartnick CJ
Adv Otorhinolaryngol 2012;73:105-8. Epub 2012 Mar 29 doi: 10.1159/000334457. PMID: 22472239
Cidofovir for the treatment of recurrent respiratory papillomatosis: a review of the literature.
Shehab N, Sweet BV, Hogikyan ND
Pharmacotherapy 2005 Jul;25(7):977-89. doi: 10.1592/phco.2005.25.7.977. PMID: 16006276
Diagnostic procedures for detection of lymph node metastases in cancer of the larynx.
Kau RJ, Alexiou C, Stimmer H, Arnold W
ORL J Otorhinolaryngol Relat Spec 2000 Jul-Aug;62(4):199-203. doi: 10.1159/000027746. PMID: 10859520
Ventriculosaccular lymphoepithelioma of the larynx: case report and literature review.
Narozny W, Betlejewski A, Stankiewicz C, Kamiński M
Head Neck 1998 Aug;20(5):425-9. doi: 10.1002/(sici)1097-0347(199808)20:5<425::aid-hed11>3.0.co;2-f. PMID: 9663671
Chondrosarcoma of the larynx: challenges in diagnosis and management.
Bogdan CJ, Maniglia AJ, Eliachar I, Katz RL
Head Neck 1994 Mar-Apr;16(2):127-34. doi: 10.1002/hed.2880160205. PMID: 8021131

Clinical prediction guides

Risk Factors for Dysplasia in Recurrent Respiratory Papillomatosis in an Adult and Pediatric Population.
Karatayli-Ozgursoy S, Bishop JA, Hillel A, Akst L, Best SR
Ann Otol Rhinol Laryngol 2016 Mar;125(3):235-41. Epub 2015 Oct 8 doi: 10.1177/0003489415608196. PMID: 26453486
Histologic correlation of expression of Ki-67 in squamous cell carcinoma of the glottis according to the degree of cell differentiation.
Bonhin RG, Carvalho GM, Guimarães AC, Chone CT, Crespo AN, Altemani AM, Amstalden EM
Braz J Otorhinolaryngol 2014 Jul-Aug;80(4):290-5. Epub 2014 Jun 11 doi: 10.1016/j.bjorl.2014.05.016. PMID: 25183178Free PMC Article
Cidofovir for the treatment of recurrent respiratory papillomatosis: a review of the literature.
Shehab N, Sweet BV, Hogikyan ND
Pharmacotherapy 2005 Jul;25(7):977-89. doi: 10.1592/phco.2005.25.7.977. PMID: 16006276
Ventriculosaccular lymphoepithelioma of the larynx: case report and literature review.
Narozny W, Betlejewski A, Stankiewicz C, Kamiński M
Head Neck 1998 Aug;20(5):425-9. doi: 10.1002/(sici)1097-0347(199808)20:5<425::aid-hed11>3.0.co;2-f. PMID: 9663671

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2024
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Head and Neck Cancers, 2024

    Consumer resources

    Reviews

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