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Papillary Carcinoma In Situ

MedGen UID:
83113
•Concept ID:
C0334242
•
Neoplastic Process
Synonym: Papillary carcinoma in situ
SNOMED CT: Papillary carcinoma in situ (10376009)

Definition

An epithelial neoplasm with a papillary growth pattern in which the malignant cells are confined to the epithelium, without evidence of invasion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPapillary Carcinoma In Situ

Professional guidelines

PubMed

European guidelines for the diagnosis, treatment and follow-up of breast lesions with uncertain malignant potential (B3 lesions) developed jointly by EUSOMA, EUSOBI, ESP (BWG) and ESSO.
Rubio IT, Wyld L, Marotti L, Athanasiou A, Regitnig P, Catanuto G, Schoones JW, Zambon M, Camps J, Santini D, Dietz J, Sardanelli F, Varga Z, Smidt M, Sharma N, Shaaban AM, Gilbert F
Eur J Surg Oncol 2024 Jan;50(1):107292. Epub 2023 Nov 27 doi: 10.1016/j.ejso.2023.107292. PMID: 38061151
Papillary neoplasms of the breast including upgrade rates and management of intraductal papilloma without atypia diagnosed at core needle biopsy.
Brogi E, Krystel-Whittemore M
Mod Pathol 2021 Jan;34(Suppl 1):78-93. Epub 2020 Oct 26 doi: 10.1038/s41379-020-00706-5. PMID: 33106592
A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas.
Basturk O, Hong SM, Wood LD, Adsay NV, Albores-Saavedra J, Biankin AV, Brosens LA, Fukushima N, Goggins M, Hruban RH, Kato Y, Klimstra DS, Klöppel G, Krasinskas A, Longnecker DS, Matthaei H, Offerhaus GJ, Shimizu M, Takaori K, Terris B, Yachida S, Esposito I, Furukawa T; Baltimore Consensus Meeting
Am J Surg Pathol 2015 Dec;39(12):1730-41. doi: 10.1097/PAS.0000000000000533. PMID: 26559377Free PMC Article

Recent clinical studies

Etiology

Papillary lesions of the breast - review and practical issues.
Ni Y, Tse GM
Semin Diagn Pathol 2022 Sep;39(5):344-354. Epub 2022 Jun 11 doi: 10.1053/j.semdp.2022.06.001. PMID: 35718581
Diagnostic cytologic sample profiles in patients with bladder cancer using TICAS system.
Koss LG, Bartels PH, Sychra JJ, Wied GL
Acta Cytol 1978 Sep-Oct;22(5):392-7. PMID: 364909
The incidence and significance of intracytoplasmic calcifications in nipple aspirate specimens.
Zimmerman AL, King EB, Barrett DL, Petrakis NL
Acta Cytol 1977 Sep-Oct;21(5):685-92. PMID: 272112

Diagnosis

Papillary lesions of the breast - review and practical issues.
Ni Y, Tse GM
Semin Diagn Pathol 2022 Sep;39(5):344-354. Epub 2022 Jun 11 doi: 10.1053/j.semdp.2022.06.001. PMID: 35718581
Role of breast magnetic resonance imaging in predicting residual lobular carcinoma in situ after initial excision.
Lee RK, Kim HJ, Lee J
Asian J Surg 2018 May;41(3):279-284. Epub 2017 Mar 9 doi: 10.1016/j.asjsur.2017.02.002. PMID: 28286021
Mixed ductal-endocrine carcinoma of the pancreas with synchronous papillary carcinoma-in-situ of the common bile duct: a case report and literature review--synchronous pancreatic and bile duct tumors.
Carter RR, Woodall CE 3rd, McNally ME, Talboy GE, Lankachandra KM, Van Way CW 3rd
Am Surg 2008 Apr;74(4):338-40. PMID: 18453301
Papillary carcinoma-in-situ of the breast presenting as a fungating lesion.
Chisholm LJ, Gupta R, Theaker JM, Royle GT
Eur J Surg Oncol 2000 Aug;26(5):517-8. doi: 10.1053/ejso.1999.0934. PMID: 11016476
Non-papillary carcinoma in situ of the bladder: a clinicopathologic study of 2 cases treated with radical cystoprostatourethrectomy.
Kano M, Iwasaki H
J Urol 1979 Jul;122(1):116-20. doi: 10.1016/s0022-5347(17)56280-1. PMID: 458975

Therapy

Role of breast magnetic resonance imaging in predicting residual lobular carcinoma in situ after initial excision.
Lee RK, Kim HJ, Lee J
Asian J Surg 2018 May;41(3):279-284. Epub 2017 Mar 9 doi: 10.1016/j.asjsur.2017.02.002. PMID: 28286021
Intracystic papillary carcinoma of the male breast: a case report and review of the literature.
Hussain A, Sweeney KJ, Salman R, Callagy GM, Sweeney I, McLaughlin R
Ir J Med Sci 2012 Sep;181(3):329-31. Epub 2009 Jul 9 doi: 10.1007/s11845-009-0372-y. PMID: 19588226

Prognosis

Role of breast magnetic resonance imaging in predicting residual lobular carcinoma in situ after initial excision.
Lee RK, Kim HJ, Lee J
Asian J Surg 2018 May;41(3):279-284. Epub 2017 Mar 9 doi: 10.1016/j.asjsur.2017.02.002. PMID: 28286021
Intracystic papillary carcinoma of the male breast: a case report and review of the literature.
Hussain A, Sweeney KJ, Salman R, Callagy GM, Sweeney I, McLaughlin R
Ir J Med Sci 2012 Sep;181(3):329-31. Epub 2009 Jul 9 doi: 10.1007/s11845-009-0372-y. PMID: 19588226

Clinical prediction guides

Role of breast magnetic resonance imaging in predicting residual lobular carcinoma in situ after initial excision.
Lee RK, Kim HJ, Lee J
Asian J Surg 2018 May;41(3):279-284. Epub 2017 Mar 9 doi: 10.1016/j.asjsur.2017.02.002. PMID: 28286021
The DNA profile of breast cancer in situ.
Pallis L, Skoog L, Falkmer U, Wilking N, Rutquist LE, Auer G, Cedermark B
Eur J Surg Oncol 1992 Apr;18(2):108-11. PMID: 1582502
Nonpapillary carcinoma in situ and atypical hyperplasia in cancerous bladders: further studies of surgically removed bladders by mapping.
Koss LG, Nakanishi I, Freed SZ
Urology 1977 Apr;9(4):442-55. doi: 10.1016/0090-4295(77)90227-8. PMID: 857375

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