U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Childhood Embryonal Rhabdomyosarcoma

MedGen UID:
83530
•Concept ID:
C0279612
•
Neoplastic Process
Synonyms: Embryonal Childhood Rhabdomyosarcoma; Pediatric Embryonal Rhabdomyosarcoma

Definition

A poorly circumscribed morphologic variant of rhabdomyosarcoma occurring in children. The neoplasm is characterized by the presence of primitive skeletal muscle in any stage of myogenesis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChildhood Embryonal Rhabdomyosarcoma

Professional guidelines

PubMed

Radiotherapy in the Management of Childhood Rhabdomyosarcoma.
Mandeville HC
Clin Oncol (R Coll Radiol) 2019 Jul;31(7):462-470. Epub 2019 Apr 13 doi: 10.1016/j.clon.2019.03.047. PMID: 30992168
Diagnosis and Management of Rhabdomyosarcoma in Children and Adolescents: ICMR Consensus Document.
Panda SP, Chinnaswamy G, Vora T, Prasad M, Bansal D, Kapoor G, Radhakrishnan V, Agarwala S, Laskar S, Arora B, Kaur T, Rath GK, Bakhshi S
Indian J Pediatr 2017 May;84(5):393-402. Epub 2017 Apr 5 doi: 10.1007/s12098-017-2315-3. PMID: 28378141
Molecular diagnostics in the management of rhabdomyosarcoma.
Arnold MA, Barr FG
Expert Rev Mol Diagn 2017 Feb;17(2):189-194. Epub 2017 Jan 6 doi: 10.1080/14737159.2017.1275965. PMID: 28058850Free PMC Article

Recent clinical studies

Etiology

A Case of Pheochromocytoma as a Subsequent Neoplasm in a Survivor of Childhood Embryonal Rhabdomyosarcoma.
Rodwin RL, Janardan SK, Hofstatter EW, Kadan-Lottick NS
J Pediatr Hematol Oncol 2022 Mar 1;44(2):e585-e588. doi: 10.1097/MPH.0000000000002270. PMID: 35200227Free PMC Article
Characteristics of gastrointestinal stromal tumors in a Middle Eastern population.
Barakat FH, Haddad HA, Matalka II, Al-Orjani MS, Al-Masri MM, Sughayer MA
Saudi Med J 2010 Jul;31(7):797-802. PMID: 20635015

Diagnosis

A Case of Pheochromocytoma as a Subsequent Neoplasm in a Survivor of Childhood Embryonal Rhabdomyosarcoma.
Rodwin RL, Janardan SK, Hofstatter EW, Kadan-Lottick NS
J Pediatr Hematol Oncol 2022 Mar 1;44(2):e585-e588. doi: 10.1097/MPH.0000000000002270. PMID: 35200227Free PMC Article

Therapy

Artesunate induces ROS- and p38 MAPK-mediated apoptosis and counteracts tumor growth in vivo in embryonal rhabdomyosarcoma cells.
Beccafico S, Morozzi G, Marchetti MC, Riccardi C, Sidoni A, Donato R, Sorci G
Carcinogenesis 2015 Sep;36(9):1071-83. Epub 2015 Jul 7 doi: 10.1093/carcin/bgv098. PMID: 26153023
Current trends in treatment of childhood rhabdomyosarcoma of lower genitourinary tract.
Belman AB, Baum ES
Urology 1976 Jul;8(1):31-4. doi: 10.1016/0090-4295(76)90048-0. PMID: 941356

Prognosis

Alternative prognostic factors in pediatric embryonal rhabdomyosarcoma: Nm23 expression, proliferative activity and angiogenesis.
Diniz G, Aktaş S, Ortaç R, Erbay A, Vergin C, Ergin M
Turk J Pediatr 2004 Jul-Sep;46(3):239-44. PMID: 15503477

Clinical prediction guides

Alternative prognostic factors in pediatric embryonal rhabdomyosarcoma: Nm23 expression, proliferative activity and angiogenesis.
Diniz G, Aktaş S, Ortaç R, Erbay A, Vergin C, Ergin M
Turk J Pediatr 2004 Jul-Sep;46(3):239-44. PMID: 15503477

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...