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Plasmacytosis

MedGen UID:
852667
Concept ID:
C0549295
Finding
HPO: HP:0030150

Definition

An abnormally increased number of plasma cells in tissues, exudates, or blood [from HPO]

Conditions with this feature

Lymphopenic hypergammaglobulinemia, antibody deficiency, autoimmune hemolytic anemia, and glomerulonephritis
MedGen UID:
340877
Concept ID:
C1855470
Disease or Syndrome

Professional guidelines

PubMed

Rajkumar SV
Am J Hematol 2022 Aug;97(8):1086-1107. Epub 2022 May 23 doi: 10.1002/ajh.26590. PMID: 35560063Free PMC Article
Rajkumar SV
Am J Hematol 2020 May;95(5):548-567. doi: 10.1002/ajh.25791. PMID: 32212178
Fajgenbaum DC, Uldrick TS, Bagg A, Frank D, Wu D, Srkalovic G, Simpson D, Liu AY, Menke D, Chandrakasan S, Lechowicz MJ, Wong RS, Pierson S, Paessler M, Rossi JF, Ide M, Ruth J, Croglio M, Suarez A, Krymskaya V, Chadburn A, Colleoni G, Nasta S, Jayanthan R, Nabel CS, Casper C, Dispenzieri A, Fosså A, Kelleher D, Kurzrock R, Voorhees P, Dogan A, Yoshizaki K, van Rhee F, Oksenhendler E, Jaffe ES, Elenitoba-Johnson KS, Lim MS
Blood 2017 Mar 23;129(12):1646-1657. Epub 2017 Jan 13 doi: 10.1182/blood-2016-10-746933. PMID: 28087540Free PMC Article

Recent clinical studies

Etiology

Khalil S, Donthi D, Gru AA
J Cutan Pathol 2022 Oct;49(10):898-916. Epub 2022 Aug 4 doi: 10.1111/cup.14264. PMID: 35656820
Rajkumar SV
Am J Hematol 2022 Aug;97(8):1086-1107. Epub 2022 May 23 doi: 10.1002/ajh.26590. PMID: 35560063Free PMC Article
Rajkumar SV
Am J Hematol 2020 May;95(5):548-567. doi: 10.1002/ajh.25791. PMID: 32212178
Fajgenbaum DC, Shilling D
Hematol Oncol Clin North Am 2018 Feb;32(1):11-21. doi: 10.1016/j.hoc.2017.09.002. PMID: 29157613
Fajgenbaum DC, Uldrick TS, Bagg A, Frank D, Wu D, Srkalovic G, Simpson D, Liu AY, Menke D, Chandrakasan S, Lechowicz MJ, Wong RS, Pierson S, Paessler M, Rossi JF, Ide M, Ruth J, Croglio M, Suarez A, Krymskaya V, Chadburn A, Colleoni G, Nasta S, Jayanthan R, Nabel CS, Casper C, Dispenzieri A, Fosså A, Kelleher D, Kurzrock R, Voorhees P, Dogan A, Yoshizaki K, van Rhee F, Oksenhendler E, Jaffe ES, Elenitoba-Johnson KS, Lim MS
Blood 2017 Mar 23;129(12):1646-1657. Epub 2017 Jan 13 doi: 10.1182/blood-2016-10-746933. PMID: 28087540Free PMC Article

Diagnosis

Khalil S, Donthi D, Gru AA
J Cutan Pathol 2022 Oct;49(10):898-916. Epub 2022 Aug 4 doi: 10.1111/cup.14264. PMID: 35656820
Rajkumar SV
Am J Hematol 2022 Aug;97(8):1086-1107. Epub 2022 May 23 doi: 10.1002/ajh.26590. PMID: 35560063Free PMC Article
Rajkumar SV
Am J Hematol 2020 May;95(5):548-567. doi: 10.1002/ajh.25791. PMID: 32212178
Fajgenbaum DC, Uldrick TS, Bagg A, Frank D, Wu D, Srkalovic G, Simpson D, Liu AY, Menke D, Chandrakasan S, Lechowicz MJ, Wong RS, Pierson S, Paessler M, Rossi JF, Ide M, Ruth J, Croglio M, Suarez A, Krymskaya V, Chadburn A, Colleoni G, Nasta S, Jayanthan R, Nabel CS, Casper C, Dispenzieri A, Fosså A, Kelleher D, Kurzrock R, Voorhees P, Dogan A, Yoshizaki K, van Rhee F, Oksenhendler E, Jaffe ES, Elenitoba-Johnson KS, Lim MS
Blood 2017 Mar 23;129(12):1646-1657. Epub 2017 Jan 13 doi: 10.1182/blood-2016-10-746933. PMID: 28087540Free PMC Article
Xie Y, Vallangeon B, Liu X, Lagoo AS
Indian J Pathol Microbiol 2016 Oct-Dec;59(4):446-456. doi: 10.4103/0377-4929.191756. PMID: 27721273

Therapy

Rajkumar SV
Am J Hematol 2022 Aug;97(8):1086-1107. Epub 2022 May 23 doi: 10.1002/ajh.26590. PMID: 35560063Free PMC Article
Rajkumar SV
Am J Hematol 2016 Jan;91(1):90-100. doi: 10.1002/ajh.24236. PMID: 26565896Free PMC Article
Wagner G, Rose C, Klapper W, Sachse MM
J Dtsch Dermatol Ges 2013 Dec;11(12):1161-7. Epub 2013 Aug 12 doi: 10.1111/ddg.12190. PMID: 23937389
Singhal S, Mehta J
Clin J Am Soc Nephrol 2006 Nov;1(6):1322-30. Epub 2006 Oct 11 doi: 10.2215/CJN.03060906. PMID: 17699365
International Myeloma Working Group
Br J Haematol 2003 Jun;121(5):749-57. PMID: 12780789

Prognosis

Rajkumar SV
Am J Hematol 2020 May;95(5):548-567. doi: 10.1002/ajh.25791. PMID: 32212178
Rajkumar SV
Am J Hematol 2016 Jan;91(1):90-100. doi: 10.1002/ajh.24236. PMID: 26565896Free PMC Article
Munoz J, Hughes A, Guo Y
Blood Coagul Fibrinolysis 2013 Jan;24(1):100-1. doi: 10.1097/MBC.0b013e32835a72df. PMID: 23103724
Singhal S, Mehta J
Clin J Am Soc Nephrol 2006 Nov;1(6):1322-30. Epub 2006 Oct 11 doi: 10.2215/CJN.03060906. PMID: 17699365
International Myeloma Working Group
Br J Haematol 2003 Jun;121(5):749-57. PMID: 12780789

Clinical prediction guides

Khalil S, Donthi D, Gru AA
J Cutan Pathol 2022 Oct;49(10):898-916. Epub 2022 Aug 4 doi: 10.1111/cup.14264. PMID: 35656820
Gordon IO, Bettenworth D, Bokemeyer A, Srivastava A, Rosty C, de Hertogh G, Robert ME, Valasek MA, Mao R, Li J, Harpaz N, Borralho P, Pai RK, Odze R, Feakins R, Parker CE, Guizzetti L, Nguyen T, Shackelton LM, Sandborn WJ, Jairath V, Baker M, Bruining D, Fletcher JG, Feagan BG, Pai RK, Rieder F; Stenosis Therapy and Anti-Fibrotic Research (STAR) Consortium
Gut 2022 Mar;71(3):479-486. Epub 2021 May 5 doi: 10.1136/gutjnl-2021-324374. PMID: 33952604Free PMC Article
Pai RK, Jairath V, Vande Casteele N, Rieder F, Parker CE, Lauwers GY
Gastrointest Endosc 2018 Dec;88(6):887-898. Epub 2018 Aug 22 doi: 10.1016/j.gie.2018.08.018. PMID: 30142351
Wagner G, Rose C, Klapper W, Sachse MM
J Dtsch Dermatol Ges 2013 Dec;11(12):1161-7. Epub 2013 Aug 12 doi: 10.1111/ddg.12190. PMID: 23937389
Singhal S, Mehta J
Clin J Am Soc Nephrol 2006 Nov;1(6):1322-30. Epub 2006 Oct 11 doi: 10.2215/CJN.03060906. PMID: 17699365

Recent systematic reviews

Belyaeva E, Rubenstein A, Pierson SK, Dalldorf D, Frank D, Lim MS, Fajgenbaum DC
Hematol Oncol 2022 Apr;40(2):191-201. Epub 2022 Feb 18 doi: 10.1002/hon.2969. PMID: 35104370Free PMC Article
Gordon IO, Bettenworth D, Bokemeyer A, Srivastava A, Rosty C, de Hertogh G, Robert ME, Valasek MA, Mao R, Li J, Harpaz N, Borralho P, Pai RK, Odze R, Feakins R, Parker CE, Guizzetti L, Nguyen T, Shackelton LM, Sandborn WJ, Jairath V, Baker M, Bruining D, Fletcher JG, Feagan BG, Pai RK, Rieder F; Stenosis Therapy and Anti-Fibrotic Research (STAR) Consortium
Gut 2022 Mar;71(3):479-486. Epub 2021 May 5 doi: 10.1136/gutjnl-2021-324374. PMID: 33952604Free PMC Article
Gupta A, Yu A, Peyrin-Biroulet L, Ananthakrishnan AN
Clin Gastroenterol Hepatol 2021 Sep;19(9):1800-1813.e4. Epub 2020 Sep 30 doi: 10.1016/j.cgh.2020.09.046. PMID: 33010406

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