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Neoplasm of fatty tissue

MedGen UID:
867518
•Concept ID:
C4021901
•
Neoplastic Process
Synonyms: Tumor of fatty tissue; Tumour of fatty tissue
 
HPO: HP:0200013

Definition

A tumor (abnormal growth of tissue) of adipose tissue. [from HPO]

Professional guidelines

PubMed

Nonalcoholic steatohepatitis-related hepatocellular carcinoma: pathogenesis and treatment.
Llovet JM, Willoughby CE, Singal AG, Greten TF, Heikenwälder M, El-Serag HB, Finn RS, Friedman SL
Nat Rev Gastroenterol Hepatol 2023 Aug;20(8):487-503. Epub 2023 Mar 17 doi: 10.1038/s41575-023-00754-7. PMID: 36932227
The double-edged sword of probiotic supplementation on gut microbiota structure in Helicobacter pylori management.
Nabavi-Rad A, Sadeghi A, Asadzadeh Aghdaei H, Yadegar A, Smith SM, Zali MR
Gut Microbes 2022 Jan-Dec;14(1):2108655. doi: 10.1080/19490976.2022.2108655. PMID: 35951774Free PMC Article
EAA clinical practice guidelines-gynecomastia evaluation and management.
Kanakis GA, Nordkap L, Bang AK, Calogero AE, Bártfai G, Corona G, Forti G, Toppari J, Goulis DG, Jørgensen N
Andrology 2019 Nov;7(6):778-793. Epub 2019 May 16 doi: 10.1111/andr.12636. PMID: 31099174

Recent clinical studies

Etiology

Metabolic pathways in obesity-related breast cancer.
Brown KA
Nat Rev Endocrinol 2021 Jun;17(6):350-363. Epub 2021 Apr 29 doi: 10.1038/s41574-021-00487-0. PMID: 33927368Free PMC Article
The Importance of Breast Adipose Tissue in Breast Cancer.
Kothari C, Diorio C, Durocher F
Int J Mol Sci 2020 Aug 11;21(16) doi: 10.3390/ijms21165760. PMID: 32796696Free PMC Article
Estrogens and breast cancer: Mechanisms involved in obesity-related development, growth and progression.
Bhardwaj P, Au CC, Benito-Martin A, Ladumor H, Oshchepkova S, Moges R, Brown KA
J Steroid Biochem Mol Biol 2019 May;189:161-170. Epub 2019 Mar 6 doi: 10.1016/j.jsbmb.2019.03.002. PMID: 30851382Free PMC Article
The obese adipose tissue microenvironment in cancer development and progression.
Quail DF, Dannenberg AJ
Nat Rev Endocrinol 2019 Mar;15(3):139-154. doi: 10.1038/s41574-018-0126-x. PMID: 30459447Free PMC Article
Role of Inactivity in Chronic Diseases: Evolutionary Insight and Pathophysiological Mechanisms.
Booth FW, Roberts CK, Thyfault JP, Ruegsegger GN, Toedebusch RG
Physiol Rev 2017 Oct 1;97(4):1351-1402. doi: 10.1152/physrev.00019.2016. PMID: 28814614Free PMC Article

Diagnosis

Lipofibromatosis.
Rastogi K, Singh L
Fetal Pediatr Pathol 2019 Dec;38(6):490-495. Epub 2019 Jun 2 doi: 10.1080/15513815.2019.1619206. PMID: 31154875
The obese adipose tissue microenvironment in cancer development and progression.
Quail DF, Dannenberg AJ
Nat Rev Endocrinol 2019 Mar;15(3):139-154. doi: 10.1038/s41574-018-0126-x. PMID: 30459447Free PMC Article
Fatty Pancreas: Should We Be Concerned?
Majumder S, Philip NA, Takahashi N, Levy MJ, Singh VP, Chari ST
Pancreas 2017 Nov/Dec;46(10):1251-1258. doi: 10.1097/MPA.0000000000000941. PMID: 29040194Free PMC Article
Gastric Angiolipoma: A Rare Entity.
Liu YJ, Karamchandani DM
Arch Pathol Lab Med 2017 Jun;141(6):862-866. doi: 10.5858/arpa.2016-0239-RS. PMID: 28557598
A practical and precise approach to quantification of body composition in cancer patients using computed tomography images acquired during routine care.
Mourtzakis M, Prado CM, Lieffers JR, Reiman T, McCargar LJ, Baracos VE
Appl Physiol Nutr Metab 2008 Oct;33(5):997-1006. doi: 10.1139/H08-075. PMID: 18923576

Therapy

Assessment of causal effects of visceral adipose tissue on risk of cancers: a Mendelian randomization study.
Lu Y, Tang H, Huang P, Wang J, Deng P, Li Y, Zheng J, Weng L
Int J Epidemiol 2022 Aug 10;51(4):1204-1218. doi: 10.1093/ije/dyac025. PMID: 35218345Free PMC Article
Comparative Outcomes of Dupuytren Disease Treatment.
Binhammer P
Hand Clin 2018 Aug;34(3):377-386. doi: 10.1016/j.hcl.2018.03.006. PMID: 30012297
Nutrition in Cancer.
Ravasco P
Nestle Nutr Inst Workshop Ser 2015;82:91-102. Epub 2015 Oct 20 doi: 10.1159/000382004. PMID: 26544599
De novo lipogenesis in health and disease.
Ameer F, Scandiuzzi L, Hasnain S, Kalbacher H, Zaidi N
Metabolism 2014 Jul;63(7):895-902. Epub 2014 Apr 12 doi: 10.1016/j.metabol.2014.04.003. PMID: 24814684
Obesity-associated mechanisms of hepatocarcinogenesis.
Karagozian R, Derdák Z, Baffy G
Metabolism 2014 May;63(5):607-17. Epub 2014 Feb 5 doi: 10.1016/j.metabol.2014.01.011. PMID: 24629562

Prognosis

Lipid-associated macrophages in the tumor-adipose microenvironment facilitate breast cancer progression.
Liu Z, Gao Z, Li B, Li J, Ou Y, Yu X, Zhang Z, Liu S, Fu X, Jin H, Wu J, Sun S, Sun S, Wu Q
Oncoimmunology 2022;11(1):2085432. Epub 2022 Jun 8 doi: 10.1080/2162402X.2022.2085432. PMID: 35712121Free PMC Article
What's new in adipocytic neoplasia?
Thway K
Histopathology 2022 Jan;80(1):76-97. doi: 10.1111/his.14548. PMID: 34958506
Gastric Angiolipoma: A Rare Entity.
Liu YJ, Karamchandani DM
Arch Pathol Lab Med 2017 Jun;141(6):862-866. doi: 10.5858/arpa.2016-0239-RS. PMID: 28557598
Obesity and Breast Cancer.
Fortner RT, Katzke V, Kühn T, Kaaks R
Recent Results Cancer Res 2016;208:43-65. doi: 10.1007/978-3-319-42542-9_3. PMID: 27909901
A practical and precise approach to quantification of body composition in cancer patients using computed tomography images acquired during routine care.
Mourtzakis M, Prado CM, Lieffers JR, Reiman T, McCargar LJ, Baracos VE
Appl Physiol Nutr Metab 2008 Oct;33(5):997-1006. doi: 10.1139/H08-075. PMID: 18923576

Clinical prediction guides

Lipid-associated macrophages in the tumor-adipose microenvironment facilitate breast cancer progression.
Liu Z, Gao Z, Li B, Li J, Ou Y, Yu X, Zhang Z, Liu S, Fu X, Jin H, Wu J, Sun S, Sun S, Wu Q
Oncoimmunology 2022;11(1):2085432. Epub 2022 Jun 8 doi: 10.1080/2162402X.2022.2085432. PMID: 35712121Free PMC Article
Obesity, Diabetes, and Increased Cancer Progression.
Kim DS, Scherer PE
Diabetes Metab J 2021 Nov;45(6):799-812. Epub 2021 Nov 22 doi: 10.4093/dmj.2021.0077. PMID: 34847640Free PMC Article
Adipocyte dedifferentiation in health and diseases.
Song T, Kuang S
Clin Sci (Lond) 2019 Oct 30;133(20):2107-2119. doi: 10.1042/CS20190128. PMID: 31654064Free PMC Article
Energy metabolism in cachexia.
Rohm M, Zeigerer A, Machado J, Herzig S
EMBO Rep 2019 Apr;20(4) Epub 2019 Mar 19 doi: 10.15252/embr.201847258. PMID: 30890538Free PMC Article
De novo lipogenesis in health and disease.
Ameer F, Scandiuzzi L, Hasnain S, Kalbacher H, Zaidi N
Metabolism 2014 Jul;63(7):895-902. Epub 2014 Apr 12 doi: 10.1016/j.metabol.2014.04.003. PMID: 24814684

Recent systematic reviews

A Systematic Review of Outcomes and Complications of Tuberous Breast Surgery.
Alvaro AI, Willet JW, Dounas GD, Jeeves A, Lodge M, Javed MU
Aesthet Surg J 2023 Nov 16;43(12):NP1001-NP1009. doi: 10.1093/asj/sjad229. PMID: 37439225
Adiposity and cancer survival: a systematic review and meta-analysis.
Cheng E, Kirley J, Cespedes Feliciano EM, Caan BJ
Cancer Causes Control 2022 Oct;33(10):1219-1246. Epub 2022 Aug 15 doi: 10.1007/s10552-022-01613-7. PMID: 35971021Free PMC Article
Prognostic Impact of Adiposity in Hematological Malignancies: A Systematic Review and Meta-analysis.
Aleixo GFP, Sheu M, Mirzai S, Majhail NS
Clin Lymphoma Myeloma Leuk 2022 Oct;22(10):726-734. Epub 2022 May 29 doi: 10.1016/j.clml.2022.05.008. PMID: 35750574
Metabolic dysfunction in polycystic ovary syndrome: Pathogenic role of androgen excess and potential therapeutic strategies.
Sanchez-Garrido MA, Tena-Sempere M
Mol Metab 2020 May;35:100937. Epub 2020 Feb 5 doi: 10.1016/j.molmet.2020.01.001. PMID: 32244180Free PMC Article
Lifestyle changes in women with polycystic ovary syndrome.
Lim SS, Hutchison SK, Van Ryswyk E, Norman RJ, Teede HJ, Moran LJ
Cochrane Database Syst Rev 2019 Mar 28;3(3):CD007506. doi: 10.1002/14651858.CD007506.pub4. PMID: 30921477Free PMC Article

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