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Uterine corpus neuroendocrine neoplasm

MedGen UID:
925580
•Concept ID:
C4288048
•
Neoplastic Process
Synonyms: body of uterus NET; body of uterus neuroendocrine neoplasm; body of uterus neuroendocrine tumor; body of uterus neuroendocrine tumor, well differentiated, low or intermediate grade; body of uterus neuroendocrine tumour; neuroendocrine neoplasm of body of uterus; Uterine Corpus Neuroendocrine Neoplasm; uterine corpus neuroendocrine neoplasm; Uterine Corpus Neuroendocrine Tumor; uterine corpus neuroendocrine tumor; uterine corpus neuroendocrine tumour
 
Monarch Initiative: MONDO:0021650

Definition

An epithelial neoplasm with neuroendocrine differentiation that arises from the uterine corpus. It includes neuroendocrine tumor G1 (carcinoid tumor), small cell carcinoma pulmonary type, and large cell neuroendocrine carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUterine corpus neuroendocrine neoplasm

Professional guidelines

PubMed

APOBEC3C is a novel target for the immune treatment of lower-grade gliomas.
Zhao S, Li Y, Xu J, Shen L
Neurol Res 2024 Mar;46(3):227-242. Epub 2024 Jan 22 doi: 10.1080/01616412.2023.2287340. PMID: 38007705
Role of radiotherapy in the management of rare gynaecological cancers.
Morcet-Delattre R, Espenel S, Tas P, Chargari C, Escande A
Cancer Radiother 2023 Dec;27(8):778-788. Epub 2023 Nov 2 doi: 10.1016/j.canrad.2023.08.006. PMID: 37925347
Cancer treatment and survivorship statistics, 2016.
Miller KD, Siegel RL, Lin CC, Mariotto AB, Kramer JL, Rowland JH, Stein KD, Alteri R, Jemal A
CA Cancer J Clin 2016 Jul;66(4):271-89. Epub 2016 Jun 2 doi: 10.3322/caac.21349. PMID: 27253694

Recent clinical studies

Etiology

Role of radiotherapy in the management of rare gynaecological cancers.
Morcet-Delattre R, Espenel S, Tas P, Chargari C, Escande A
Cancer Radiother 2023 Dec;27(8):778-788. Epub 2023 Nov 2 doi: 10.1016/j.canrad.2023.08.006. PMID: 37925347
Cancer statistics, 2023.
Siegel RL, Miller KD, Wagle NS, Jemal A
CA Cancer J Clin 2023 Jan;73(1):17-48. doi: 10.3322/caac.21763. PMID: 36633525
Long-Term Survival and Causes of Death After Diagnoses of Common Cancers in 3 Cohorts of US Health Professionals.
Cheng E, Lee DH, Tamimi RM, Hankinson SE, Willett WC, Giovannucci EL, Eliassen AH, Stampfer MJ, Mucci LA, Fuchs CS, Spiegelman D
JNCI Cancer Spectr 2022 Mar 2;6(2) doi: 10.1093/jncics/pkac021. PMID: 35603853Free PMC Article
Clinical comparison between neuroendocrine and endometrioid type carcinoma of the uterine corpus.
Mei S, Gibbs J, Economos K, Lee YC, Kanis MJ
J Gynecol Oncol 2019 Jul;30(4):e58. Epub 2019 Feb 22 doi: 10.3802/jgo.2019.30.e58. PMID: 31074241Free PMC Article
Cancer treatment and survivorship statistics, 2016.
Miller KD, Siegel RL, Lin CC, Mariotto AB, Kramer JL, Rowland JH, Stein KD, Alteri R, Jemal A
CA Cancer J Clin 2016 Jul;66(4):271-89. Epub 2016 Jun 2 doi: 10.3322/caac.21349. PMID: 27253694

Diagnosis

APOBEC3C is a novel target for the immune treatment of lower-grade gliomas.
Zhao S, Li Y, Xu J, Shen L
Neurol Res 2024 Mar;46(3):227-242. Epub 2024 Jan 22 doi: 10.1080/01616412.2023.2287340. PMID: 38007705
Role of radiotherapy in the management of rare gynaecological cancers.
Morcet-Delattre R, Espenel S, Tas P, Chargari C, Escande A
Cancer Radiother 2023 Dec;27(8):778-788. Epub 2023 Nov 2 doi: 10.1016/j.canrad.2023.08.006. PMID: 37925347
Long-Term Survival and Causes of Death After Diagnoses of Common Cancers in 3 Cohorts of US Health Professionals.
Cheng E, Lee DH, Tamimi RM, Hankinson SE, Willett WC, Giovannucci EL, Eliassen AH, Stampfer MJ, Mucci LA, Fuchs CS, Spiegelman D
JNCI Cancer Spectr 2022 Mar 2;6(2) doi: 10.1093/jncics/pkac021. PMID: 35603853Free PMC Article
Clinical comparison between neuroendocrine and endometrioid type carcinoma of the uterine corpus.
Mei S, Gibbs J, Economos K, Lee YC, Kanis MJ
J Gynecol Oncol 2019 Jul;30(4):e58. Epub 2019 Feb 22 doi: 10.3802/jgo.2019.30.e58. PMID: 31074241Free PMC Article
Cancer treatment and survivorship statistics, 2016.
Miller KD, Siegel RL, Lin CC, Mariotto AB, Kramer JL, Rowland JH, Stein KD, Alteri R, Jemal A
CA Cancer J Clin 2016 Jul;66(4):271-89. Epub 2016 Jun 2 doi: 10.3322/caac.21349. PMID: 27253694

Therapy

An integrative pan cancer analysis of RET aberrations and their potential clinical implications.
Zhou L, Li J, Zhang X, Xu Z, Yan Y, Hu K
Sci Rep 2022 Aug 17;12(1):13913. doi: 10.1038/s41598-022-17791-y. PMID: 35978072Free PMC Article
Large cell neuroendocrine carcinoma with sarcomatous changes of the endometrium: a case report with immunohistochemical studies and molecular genetic study of KIT and PDGFRA.
Terada T
Pathol Res Pract 2010 Jun 15;206(6):420-5. Epub 2010 Feb 26 doi: 10.1016/j.prp.2009.12.008. PMID: 20189318
Primary primitive neuroectodermal tumor of the uterus: a case report.
Akbayir O, Güngördük K, Rafioğlu G, Gülkilik A, Yavuz E, Tekirdağ AI, Odabaş E
Arch Gynecol Obstet 2008 Apr;277(4):345-8. Epub 2007 Sep 6 doi: 10.1007/s00404-007-0451-0. PMID: 17823807
A meta-analysis of second cancers after a diagnosis of nonmelanoma skin cancer: additional evidence that solar ultraviolet-B irradiance reduces the risk of internal cancers.
Grant WB
J Steroid Biochem Mol Biol 2007 Mar;103(3-5):668-74. Epub 2007 Jan 8 doi: 10.1016/j.jsbmb.2006.12.030. PMID: 17208438
Carcinoid tumor of the uterine corpus. A case report.
González-Bosquet E, González-Bosquet J, García Jiménez A, Gil A, Xercavins J
J Reprod Med 1998 Sep;43(9):844-6. PMID: 9777628

Prognosis

Cancer statistics, 2024.
Siegel RL, Giaquinto AN, Jemal A
CA Cancer J Clin 2024 Jan-Feb;74(1):12-49. Epub 2024 Jan 17 doi: 10.3322/caac.21820. PMID: 38230766
Role of radiotherapy in the management of rare gynaecological cancers.
Morcet-Delattre R, Espenel S, Tas P, Chargari C, Escande A
Cancer Radiother 2023 Dec;27(8):778-788. Epub 2023 Nov 2 doi: 10.1016/j.canrad.2023.08.006. PMID: 37925347
Cancer statistics, 2023.
Siegel RL, Miller KD, Wagle NS, Jemal A
CA Cancer J Clin 2023 Jan;73(1):17-48. doi: 10.3322/caac.21763. PMID: 36633525
DNA Methylation Module Network-Based Prognosis and Molecular Typing of Cancer.
Cui ZJ, Zhou XH, Zhang HY
Genes (Basel) 2019 Jul 28;10(8) doi: 10.3390/genes10080571. PMID: 31357729Free PMC Article
Cancer treatment and survivorship statistics, 2016.
Miller KD, Siegel RL, Lin CC, Mariotto AB, Kramer JL, Rowland JH, Stein KD, Alteri R, Jemal A
CA Cancer J Clin 2016 Jul;66(4):271-89. Epub 2016 Jun 2 doi: 10.3322/caac.21349. PMID: 27253694

Clinical prediction guides

APOBEC3C is a novel target for the immune treatment of lower-grade gliomas.
Zhao S, Li Y, Xu J, Shen L
Neurol Res 2024 Mar;46(3):227-242. Epub 2024 Jan 22 doi: 10.1080/01616412.2023.2287340. PMID: 38007705
Non-SMC condensin I complex subunit D2 (NCAPD2) reveals its prognostic and immunologic features in human cancers.
Dong X, Liu T, Li Z, Zhai Y
Aging (Albany NY) 2023 Jul 26;15(14):7237-7257. doi: 10.18632/aging.204904. PMID: 37498296Free PMC Article
The BRCAness Landscape of Cancer.
Guo M, Wang SM
Cells 2022 Dec 1;11(23) doi: 10.3390/cells11233877. PMID: 36497135Free PMC Article
Long-Term Survival and Causes of Death After Diagnoses of Common Cancers in 3 Cohorts of US Health Professionals.
Cheng E, Lee DH, Tamimi RM, Hankinson SE, Willett WC, Giovannucci EL, Eliassen AH, Stampfer MJ, Mucci LA, Fuchs CS, Spiegelman D
JNCI Cancer Spectr 2022 Mar 2;6(2) doi: 10.1093/jncics/pkac021. PMID: 35603853Free PMC Article
Clinical comparison between neuroendocrine and endometrioid type carcinoma of the uterine corpus.
Mei S, Gibbs J, Economos K, Lee YC, Kanis MJ
J Gynecol Oncol 2019 Jul;30(4):e58. Epub 2019 Feb 22 doi: 10.3802/jgo.2019.30.e58. PMID: 31074241Free PMC Article

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