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zitB Zn(2(+))/Cd(2(+))/Ni(2(+))/Cu(2(+)) exporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945348, updated on 27-Nov-2023

Summary

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Gene symbol
zitB
Gene description
Zn(2(+))/Cd(2(+))/Ni(2(+))/Cu(2(+)) exporter
Primary source
ASAP:ABE-0002549
Locus tag
b0752
See related
ECOCYC:G6393
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0741; ybgR
Summary
ZitB (formerly known as YbgR) is a probable Zn2+ transporter. [More information is available at EcoCyc: G6393].
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Genomic context

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Sequence:
NC_000913.3 (783882..784823, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Lys Neighboring gene quinolinate synthase Neighboring gene nicotinamide riboside transporter Neighboring gene PF13985 family protein YbgS Neighboring gene 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Probing metal ion substrate-binding to the E. coli ZitB exporter in native membranes by solid state NMR. Rahman M, et al. Mol Membr Biol, 2008 Dec. PMID 19039702
  2. Characteristics of zinc transport by two bacterial cation diffusion facilitators from Ralstonia metallidurans CH34 and Escherichia coli. Anton A, et al. J Bacteriol, 2004 Nov. PMID 15516561, Free PMC Article
  3. Kinetic study of the antiport mechanism of an Escherichia coli zinc transporter, ZitB. Chao Y, et al. J Biol Chem, 2004 Mar 26. PMID 14715669
  4. ZitB (YbgR), a member of the cation diffusion facilitator family, is an additional zinc transporter in Escherichia coli. Grass G, et al. J Bacteriol, 2001 Aug. PMID 11443104, Free PMC Article
  5. Experimentally based topology models for E. coli inner membrane proteins. Rapp M, et al. Protein Sci, 2004 Apr. PMID 15044727, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Charged or polar amino acyl residues located within or adjacent to membrane-spanning regions of the protein were essential for the full function of the proteins, cation export or for proton import
    Title: Characteristics of zinc transport by two bacterial cation diffusion facilitators from Ralstonia metallidurans CH34 and Escherichia coli.
Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables monoatomic cation transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in monoatomic cation transport IEA
Inferred from Electronic Annotation
more info
  
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in zinc ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in zinc ion transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within zinc ion transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Zn(2(+))/Cd(2(+))/Ni(2(+))/Cu(2(+)) exporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    783882..784823 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415273.1 Zn(2(+))/Cd(2(+))/Ni(2(+))/Cu(2(+)) exporter [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415273.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5D8MSV4
    Conserved Domains (1) summary
    PRK03557
    Location:1 → 312
    PRK03557; CDF family zinc transporter ZitB
Nucleotide Protein
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