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pheT phenylalanine--tRNA ligase subunit beta [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945382, updated on 2-May-2024

Summary

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Gene symbol
pheT
Gene description
phenylalanine--tRNA ligase subunit beta
Primary source
ASAP:ABE-0005717
Locus tag
b1713
See related
ECOCYC:EG10710
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1711
Summary
HT_Cmplx7_Cyt: [More information is available at EcoGene: EG10710]. The subunit of PheRS contains the Phe-tRNAPhe binding site . [More information is available at EcoCyc: EG10710].
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Genomic context

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Sequence:
NC_000913.3 (1795557..1797944, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene vitamin B12 ABC transporter membrane subunit Neighboring gene integration host factor subunit alpha Neighboring gene phenylalanine--tRNA ligase subunit alpha Neighboring gene pheST-ihfA operon leader peptide

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phenylalanyl-tRNA synthetase from E. coli MRE-600: analysis of the active site distribution on the enzyme subunits by affinity labelling. Khodyreva SN, et al. Biochim Biophys Acta, 1985 Aug 8. PMID 3893548
  2. A new protein engineering approach combining chemistry and biology, part I; site-specific incorporation of 4-iodo-L-phenylalanine in vitro by using misacylated suppressor tRNAPhe. Kodama K, et al. Chembiochem, 2006 Oct. PMID 16969782
  3. In vitro selection of small RNAs that bind to Escherichia coli phenylalanyl-tRNA synthetase. Peterson ET, et al. J Mol Biol, 1994 Sep 23. PMID 8089840
  4. Alterations at the 3'-CCA end of Escherichia coli and Thermus thermophilus tRNA(Phe) do not abolish their acceptor activity. Moor NA, et al. FEBS Lett, 1994 Sep 5. PMID 8082771
  5. Substrate specificity is determined by amino acid binding pocket size in Escherichia coli phenylalanyl-tRNA synthetase. Ibba M, et al. Biochemistry, 1994 Jun 14. PMID 8003476

See all (76) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Phe-tRNA synthase beta subunit editing is essential for faithful translation of the genetic code.
    Title: Post-transfer editing in vitro and in vivo by the beta subunit of phenylalanyl-tRNA synthetase.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables aminoacyl-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
contributes_to phenylalanine-tRNA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phenylalanine-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables tRNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in phenylalanyl-tRNA aminoacylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in phenylalanyl-tRNA aminoacylation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phenylalanyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phenylalanyl-tRNA aminoacylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane HDA PubMed 
part_of phenylalanine-tRNA ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of phenylalanine-tRNA ligase complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of phenylalanine-tRNA ligase complex IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
phenylalanine--tRNA ligase subunit beta
NP_416228.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1795557..1797944 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416228.1 phenylalanine--tRNA ligase subunit beta [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416228.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T5Z9I6
    Conserved Domains (1) summary
    PRK00629
    Location:1 → 795
    pheT; phenylalanyl-tRNA synthetase subunit beta; Reviewed
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
6OZ5_B.1
6OZ5_D.1
6P26_B.1
6P26_D.1

Gene LinkOut

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