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Malignant germ cell tumor of ovary

MedGen UID:
87544
•Concept ID:
C0346180
•
Neoplastic Process
Synonym: Ovarian germ cell cancer
SNOMED CT: Malignant germ cell tumor of ovary (254869000)
Modes of inheritance:
Unknown inheritance
MedGen UID:
989040
•Concept ID:
CN307042
•
Finding
Source: Orphanet
Hereditary clinical entity whose mode of inheritance is unknown.
See: This record
Unknown inheritance (Orphanet)
 
Monarch Initiative: MONDO:0018171
OMIM®: 603737
Orphanet: ORPHA35807

Definition

Ovarian germ cell cancers are malignancies that arise from germ cells of the embryonic gonad. Although benign germ cell tumors are relatively common, accounting for approximately 20% of all ovarian neoplasms, malignant ovarian germ cell tumors are rare. Weiss et al. (1977) estimated that less than 5% of ovarian cancers are of germ cell origin. [from OMIM]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Malignant germ cell tumor of ovary
Follow this link to review classifications for Malignant germ cell tumor of ovary in Orphanet.

Professional guidelines

PubMed

Therapeutic Management of Rare Primary Ovarian Neoplasms: Carcinosarcoma, Leiomyosarcoma, Melanoma and Carcinoid.
Kozłowski M, Nowak K, Kordek A, Cymbaluk-Płoska A
Int J Environ Res Public Health 2021 Jul 23;18(15) doi: 10.3390/ijerph18157819. PMID: 34360112Free PMC Article
Primary malignant ovarian carcinoid; management and outcomes.
Nasioudis D, Frey MK, Chapman-Davis E, Caputo TA, Holcomb K
Gynecol Oncol 2020 Apr;157(1):101-105. Epub 2020 Jan 17 doi: 10.1016/j.ygyno.2020.01.002. PMID: 31959493
Non-epithelial ovarian cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Ray-Coquard I, Morice P, Lorusso D, Prat J, Oaknin A, Pautier P, Colombo N; ESMO Guidelines Committee
Ann Oncol 2018 Oct 1;29(Suppl 4):iv1-iv18. doi: 10.1093/annonc/mdy001. PMID: 29697741

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Ovarian Cancer Including Fallopian Tube Cancer and Primary Peritoneal Cancer, 2024

UK NICE Clinical guideline (CG122), Ovarian cancer: recognition and initial management, 2023

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2024
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Ovarian Cancer Including Fallopian Tube Cancer and Primary Peritoneal Cancer, 2024
    • NICE, 2023
      UK NICE Clinical guideline (CG122), Ovarian cancer: recognition and initial management, 2023

    Reviews

    Related information

    • ClinVar
      Related medical variations
    • MeSH
      Related Medical Subject Headings
    • OMIM
      Related records in OMIM
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed
    • PubMed (OMIM)
      Related literature resources in PubMed

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