Chassagnole2002_Carbon_Metabolism

Model Identifier
BIOMD0000000051
Short description

The model reproduces Figures 4,5 and 6 of the publication. The analytical functions for cometabolites Catp, Camp, Cnadph, and Cnadp slightly differ from the equations given in the paper. These changes were made in consultation with Dr. Christophe Chassagnole and are essential for reproducing the figures. The dependency of the rate of change of extracellular glucose concentration on the ratio of biomass concentration to specific weight of biomass (Cx*rPTS/Rhox) is taken into account by appropriately adjusting the stoichiometries of the species involved in the phosphotransferase system (rPTS). The rmax values for the various reactions are obtained from experiments and are not provided in the paper. However, these were personally communicated to the JWS repository. The model has been successfully tested on MathSBML.

SBML level 2 code generated for the JWS Online project by Jacky Snoep using PySCeS
Run this model online at http://jjj.biochem.sun.ac.za
To cite JWS Online please refer to: Olivier, B.G. and Snoep, J.L. (2004) Web-based modelling using JWS Online , Bioinformatics, 20:2143-2144


To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.

In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not.


To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.

Format
SBML (L2V1)
Related Publication
  • Dynamic modeling of the central carbon metabolism of Escherichia coli.
  • Christophe Chassagnole, Naruemol Noisommit-Rizzi, Joachim W Schmid, Klaus Mauch, Matthias Reuss
  • Biotechnology and bioengineering , 7/ 2002 , Volume 79 , Issue 1 , pages: 53-73 , PubMed ID: 17590932
Contributors
Submitter of the first revision: Harish Dharuri
Submitter of this revision: Lucian Smith
Curator: Lucian Smith
Modeller: Harish Dharuri

Metadata information

is (2 statements)
BioModels Database BIOMD0000000051
BioModels Database MODEL6624119661

isDescribedBy (1 statement)
PubMed 17590932

hasTaxon (1 statement)
Taxonomy Escherichia coli

hasPart (5 statements)
hasProperty (1 statement)
Mathematical Modelling Ontology Ordinary differential equation model


Curation status
Curated


Connected external resources