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Anti-erythrocyte autoantibody positivity

MedGen UID:
1052605
•Concept ID:
CN376984
•
Finding
Synonym: Antierythrocyte autoantibody positivity
 
HPO: HP:6000388

Definition

The presence of an antibody in the blood circulation that is directed against an antigen on the surface of erythrocytes (red-blood cells). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnti-erythrocyte autoantibody positivity

Professional guidelines

PubMed

Use of steroids in the management of low-risk myelodysplastic syndromes with autoimmune features.
Fattizzo B, Serpenti F, Versino F, Cassanello G, Cro LM, Barbieri M, Croci GA, Revelli N, Della Porta MG, Barcellini W
Blood Transfus 2023 Sep;21(5):452-460. Epub 2022 Dec 22 doi: 10.2450/2022.0184-22. PMID: 36580026Free PMC Article
Autoimmune haemolytic anaemia: pattern of presentation and management outcome in a Nigerian population: a ten-year experience.
Salawu L, Durosinmi MA
Afr J Med Med Sci 2002 Jun;31(2):97-100. PMID: 12518900

Recent clinical studies

Etiology

Use of steroids in the management of low-risk myelodysplastic syndromes with autoimmune features.
Fattizzo B, Serpenti F, Versino F, Cassanello G, Cro LM, Barbieri M, Croci GA, Revelli N, Della Porta MG, Barcellini W
Blood Transfus 2023 Sep;21(5):452-460. Epub 2022 Dec 22 doi: 10.2450/2022.0184-22. PMID: 36580026Free PMC Article
Increased prevalence of autoimmune phenomena in myelofibrosis: relationship with clinical and morphological characteristics, and with immunoregulatory cytokine patterns.
Barcellini W, Iurlo A, Radice T, Imperiali FG, Zaninoni A, Fattizzo B, Guidotti F, Bianchi P, Fermo E, Consonni D, Cortelezzi A
Leuk Res 2013 Nov;37(11):1509-15. Epub 2013 Sep 12 doi: 10.1016/j.leukres.2013.09.001. PMID: 24080022
Comparison of traditional methods and mitogen-stimulated direct antiglobulin test for detection of anti-red blood cell autoimmunity.
Barcellini W, Revelli N, Imperiali FG, Villa MA, Manera MC, Paccapelo C, Zaninoni A, Zanella A
Int J Hematol 2010 Jun;91(5):762-9. Epub 2010 May 8 doi: 10.1007/s12185-010-0578-9. PMID: 20454945
Sjögren's syndrome and pregnancy.
Takaya M, Ichikawa Y, Shimizu H, Uchiyama M, Moriuchi J, Arimori S
Tokai J Exp Clin Med 1991 Jul;16(2):83-8. PMID: 1780917
Anti-erythrocyte antibodies in ulcerative colitis: case report and discussion on the pathophysiology of anti-erythrocyte antibody.
Chiba M, Nakajima K, Arakawa H, Masamune O, Narisawa T
Gastroenterol Jpn 1988 Oct;23(5):564-9. doi: 10.1007/BF02779490. PMID: 3215440

Diagnosis

Coordinating Care Across the Perinatal Continuum in Hemolytic Disease of the Fetus and Newborn: The Timely Handoff of a Positive Maternal Anti-Erythrocyte Antibody Screen.
Vats K, Watchko JF
J Pediatr 2019 Nov;214:212-216. Epub 2019 Aug 23 doi: 10.1016/j.jpeds.2019.07.014. PMID: 31451186
Cold agglutinin-induced haemolysis in association with antinuclear antibody-negative SLE.
Chaubey VK, Chhabra L
BMJ Case Rep 2013 Jun 10;2013 doi: 10.1136/bcr-2013-009337. PMID: 23761498Free PMC Article
Comparison of traditional methods and mitogen-stimulated direct antiglobulin test for detection of anti-red blood cell autoimmunity.
Barcellini W, Revelli N, Imperiali FG, Villa MA, Manera MC, Paccapelo C, Zaninoni A, Zanella A
Int J Hematol 2010 Jun;91(5):762-9. Epub 2010 May 8 doi: 10.1007/s12185-010-0578-9. PMID: 20454945
Autoimmune haemolytic anaemia: pattern of presentation and management outcome in a Nigerian population: a ten-year experience.
Salawu L, Durosinmi MA
Afr J Med Med Sci 2002 Jun;31(2):97-100. PMID: 12518900
Anti-erythrocyte antibodies in ulcerative colitis: case report and discussion on the pathophysiology of anti-erythrocyte antibody.
Chiba M, Nakajima K, Arakawa H, Masamune O, Narisawa T
Gastroenterol Jpn 1988 Oct;23(5):564-9. doi: 10.1007/BF02779490. PMID: 3215440

Therapy

Use of steroids in the management of low-risk myelodysplastic syndromes with autoimmune features.
Fattizzo B, Serpenti F, Versino F, Cassanello G, Cro LM, Barbieri M, Croci GA, Revelli N, Della Porta MG, Barcellini W
Blood Transfus 2023 Sep;21(5):452-460. Epub 2022 Dec 22 doi: 10.2450/2022.0184-22. PMID: 36580026Free PMC Article
Cold agglutinin-induced haemolysis in association with antinuclear antibody-negative SLE.
Chaubey VK, Chhabra L
BMJ Case Rep 2013 Jun 10;2013 doi: 10.1136/bcr-2013-009337. PMID: 23761498Free PMC Article
Hemolytic anemia after renal transplantation: analysis of case reports.
Debska-Slizień A, Chamienia A, Król E, Zdrojewski Z, Pirski I, Zadrozny D, Sledziński Z, Rutkowski B
Transplant Proc 2003 Sep;35(6):2233-7. doi: 10.1016/s0041-1345(03)00774-7. PMID: 14529899
Autoimmune haemolytic anaemia: pattern of presentation and management outcome in a Nigerian population: a ten-year experience.
Salawu L, Durosinmi MA
Afr J Med Med Sci 2002 Jun;31(2):97-100. PMID: 12518900

Prognosis

Use of steroids in the management of low-risk myelodysplastic syndromes with autoimmune features.
Fattizzo B, Serpenti F, Versino F, Cassanello G, Cro LM, Barbieri M, Croci GA, Revelli N, Della Porta MG, Barcellini W
Blood Transfus 2023 Sep;21(5):452-460. Epub 2022 Dec 22 doi: 10.2450/2022.0184-22. PMID: 36580026Free PMC Article
Reduced 25-OH vitamin D in patients with autoimmune cytopenias, clinical correlations and literature review.
Fattizzo B, Zaninoni A, Giannotta JA, Binda F, Cortelezzi A, Barcellini W
Autoimmun Rev 2016 Jul;15(7):770-5. Epub 2016 Mar 14 doi: 10.1016/j.autrev.2016.03.015. PMID: 26988993
Increased prevalence of autoimmune phenomena in myelofibrosis: relationship with clinical and morphological characteristics, and with immunoregulatory cytokine patterns.
Barcellini W, Iurlo A, Radice T, Imperiali FG, Zaninoni A, Fattizzo B, Guidotti F, Bianchi P, Fermo E, Consonni D, Cortelezzi A
Leuk Res 2013 Nov;37(11):1509-15. Epub 2013 Sep 12 doi: 10.1016/j.leukres.2013.09.001. PMID: 24080022
Hemolytic anemia after renal transplantation: analysis of case reports.
Debska-Slizień A, Chamienia A, Król E, Zdrojewski Z, Pirski I, Zadrozny D, Sledziński Z, Rutkowski B
Transplant Proc 2003 Sep;35(6):2233-7. doi: 10.1016/s0041-1345(03)00774-7. PMID: 14529899
Autoimmune haemolytic anaemia: pattern of presentation and management outcome in a Nigerian population: a ten-year experience.
Salawu L, Durosinmi MA
Afr J Med Med Sci 2002 Jun;31(2):97-100. PMID: 12518900

Clinical prediction guides

Use of steroids in the management of low-risk myelodysplastic syndromes with autoimmune features.
Fattizzo B, Serpenti F, Versino F, Cassanello G, Cro LM, Barbieri M, Croci GA, Revelli N, Della Porta MG, Barcellini W
Blood Transfus 2023 Sep;21(5):452-460. Epub 2022 Dec 22 doi: 10.2450/2022.0184-22. PMID: 36580026Free PMC Article
Similar cytokine responses and degrees of anemia in patients with Plasmodium falciparum and Plasmodium vivax infections in the Brazilian Amazon region.
Fernandes AA, Carvalho LJ, Zanini GM, Ventura AM, Souza JM, Cotias PM, Silva-Filho IL, Daniel-Ribeiro CT
Clin Vaccine Immunol 2008 Apr;15(4):650-8. Epub 2008 Feb 6 doi: 10.1128/CVI.00475-07. PMID: 18256207Free PMC Article
Reactivity patterns of anti-phospholipid antibodies in systemic lupus erythematosus sera in relation to erythrocyte binding and complement activation.
Arvieux J, Roussel B, Ponard D, Colomb MG
Clin Exp Immunol 1991 Jun;84(3):466-71. PMID: 2044227Free PMC Article
Autoantibody against erythrocyte protein 4.1 in a patient with autoimmune hemolytic anemia.
Wakui H, Imai H, Kobayashi R, Itoh H, Notoya T, Yoshida K, Nakamoto Y, Miura AB
Blood 1988 Aug;72(2):408-12. PMID: 3401589
Anti-erythrocyte autoimmunisation during chronic falciparum malaria.
Lefrancois G, Bouvet E, Le Bras J, Vroklans M, Simonneau M, Vachon F
Lancet 1981 Sep 26;2(8248):661-4. doi: 10.1016/s0140-6736(81)90998-3. PMID: 6116046

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