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Adult Liver Carcinoma

MedGen UID:
113093
Concept ID:
C0220630
Neoplastic Process
Synonyms: Adult Primary Cancer of Liver; Adult Primary Cancer of the Liver; Adult Primary Liver Cancer; Adult Primary Liver Carcinoma

Definition

A hepatocellular carcinoma or intrahepatic cholangiocarcinoma that occurs during adulthood. [from NCI]

Professional guidelines

PubMed

Wang B, Bonkovsky HL, Lim JK, Balwani M
Gastroenterology 2023 Mar;164(3):484-491. Epub 2023 Jan 13 doi: 10.1053/j.gastro.2022.11.034. PMID: 36642627Free PMC Article
Wilkins T, Sams R, Carpenter M
Am Fam Physician 2019 Mar 1;99(5):314-323. PMID: 30811163
Kulik L, El-Serag HB
Gastroenterology 2019 Jan;156(2):477-491.e1. Epub 2018 Oct 24 doi: 10.1053/j.gastro.2018.08.065. PMID: 30367835Free PMC Article

Recent clinical studies

Etiology

Zentner D, Phan K, Gorelik A, Keung C, Grigg L, Sood S, Gibson R, Nicoll AJ
Heart Lung Circ 2023 Apr;32(4):535-543. Epub 2023 Jan 13 doi: 10.1016/j.hlc.2022.12.007. PMID: 36642589
Kogiso T, Tokushige K
Sci Rep 2020 Dec 10;10(1):21742. doi: 10.1038/s41598-020-78840-y. PMID: 33303924Free PMC Article
Ranganathan S, Lopez-Terrada D, Alaggio R
Pediatr Dev Pathol 2020 Mar-Apr;23(2):79-95. Epub 2019 Sep 25 doi: 10.1177/1093526619875228. PMID: 31554479
Kulik L, El-Serag HB
Gastroenterology 2019 Jan;156(2):477-491.e1. Epub 2018 Oct 24 doi: 10.1053/j.gastro.2018.08.065. PMID: 30367835Free PMC Article
Reuben A
Clin Liver Dis 2015 May;19(2):xiii-xvi. doi: 10.1016/j.cld.2015.02.001. PMID: 25921673

Diagnosis

Zentner D, Phan K, Gorelik A, Keung C, Grigg L, Sood S, Gibson R, Nicoll AJ
Heart Lung Circ 2023 Apr;32(4):535-543. Epub 2023 Jan 13 doi: 10.1016/j.hlc.2022.12.007. PMID: 36642589
Ranganathan S, Lopez-Terrada D, Alaggio R
Pediatr Dev Pathol 2020 Mar-Apr;23(2):79-95. Epub 2019 Sep 25 doi: 10.1177/1093526619875228. PMID: 31554479
Kulik L, El-Serag HB
Gastroenterology 2019 Jan;156(2):477-491.e1. Epub 2018 Oct 24 doi: 10.1053/j.gastro.2018.08.065. PMID: 30367835Free PMC Article
Vyas M, Jain D
Indian J Pathol Microbiol 2018 Jan-Mar;61(1):2-17. doi: 10.4103/IJPM.IJPM_578_17. PMID: 29567877
European Association For The Study Of The Liver; European Organisation For Research And Treatment Of Cancer
J Hepatol 2012 Apr;56(4):908-43. doi: 10.1016/j.jhep.2011.12.001. PMID: 22424438

Therapy

Wu F, Chen B, Dong D, Rong W, Wang H, Wang L, Wang S, Jin J, Song Y, Liu Y, Fang H, Tang Y, Li N, Zhu X, Li Y, Wang W, Wu J
JAMA Surg 2022 Dec 1;157(12):1089-1096. doi: 10.1001/jamasurg.2022.4702. PMID: 36197682Free PMC Article
Kim TH, Koh YH, Kim BH, Kim MJ, Lee JH, Park B, Park JW
J Hepatol 2021 Mar;74(3):603-612. Epub 2020 Oct 5 doi: 10.1016/j.jhep.2020.09.026. PMID: 33031846
Sonbol MB, Riaz IB, Naqvi SAA, Almquist DR, Mina S, Almasri J, Shah S, Almader-Douglas D, Uson Junior PLS, Mahipal A, Ma WW, Jin Z, Mody K, Starr J, Borad MJ, Ahn DH, Murad MH, Bekaii-Saab T
JAMA Oncol 2020 Dec 1;6(12):e204930. Epub 2020 Dec 10 doi: 10.1001/jamaoncol.2020.4930. PMID: 33090186Free PMC Article
Yamashita T, Kudo M, Ikeda K, Izumi N, Tateishi R, Ikeda M, Aikata H, Kawaguchi Y, Wada Y, Numata K, Inaba Y, Kuromatsu R, Kobayashi M, Okusaka T, Tamai T, Kitamura C, Saito K, Haruna K, Okita K, Kumada H
J Gastroenterol 2020 Jan;55(1):113-122. Epub 2019 Nov 12 doi: 10.1007/s00535-019-01642-1. PMID: 31720835Free PMC Article
Yoon SM, Ryoo BY, Lee SJ, Kim JH, Shin JH, An JH, Lee HC, Lim YS
JAMA Oncol 2018 May 1;4(5):661-669. doi: 10.1001/jamaoncol.2017.5847. PMID: 29543938Free PMC Article

Prognosis

Varol Fİ
J Gastrointest Cancer 2020 Dec;51(4):1169-1175. doi: 10.1007/s12029-020-00494-w. PMID: 32856229
Mazzaferro V, Citterio D, Bhoori S, Bongini M, Miceli R, De Carlis L, Colledan M, Salizzoni M, Romagnoli R, Antonelli B, Vivarelli M, Tisone G, Rossi M, Gruttadauria S, Di Sandro S, De Carlis R, Lucà MG, De Giorgio M, Mirabella S, Belli L, Fagiuoli S, Martini S, Iavarone M, Svegliati Baroni G, Angelico M, Ginanni Corradini S, Volpes R, Mariani L, Regalia E, Flores M, Droz Dit Busset M, Sposito C
Lancet Oncol 2020 Jul;21(7):947-956. doi: 10.1016/S1470-2045(20)30224-2. PMID: 32615109
Reccia I, Kumar J, Kusano T, Giakoustidis A, Zanellato A, Retsas P, Habib N, Jiao L, Spalding D, Pai M
Surg Oncol 2018 Sep;27(3):415-420. Epub 2018 May 29 doi: 10.1016/j.suronc.2018.05.024. PMID: 30217296
Lee SH, Lee JS, Na GH, You YK, Kim DG
Clin Transplant 2017 Jan;31(1) Epub 2016 Nov 11 doi: 10.1111/ctr.12852. PMID: 27653235
Qian Y, Fan JG
Hepatobiliary Pancreat Dis Int 2005 May;4(2):173-7. PMID: 15908310

Clinical prediction guides

Hassan OT, Behr SC, Ohliger MA, Fowler KJ, Gill RM, Fidelman N, Mehta N, Choi HH
Radiology 2023 Dec;309(3):e222776. doi: 10.1148/radiol.222776. PMID: 38112541
Nascimbeni F, Ballestri S, Machado MV, Mantovani A, Cortez-Pinto H, Targher G, Lonardo A
Expert Rev Gastroenterol Hepatol 2018 Apr;12(4):351-367. Epub 2017 Dec 26 doi: 10.1080/17474124.2018.1415756. PMID: 29224471
Wang J, Zhang S, Wu J, Lu Z, Yang J, Wu H, Chen H, Lin B, Cao T
Mol Med Rep 2017 Jul;16(1):499-506. Epub 2017 May 31 doi: 10.3892/mmr.2017.6660. PMID: 28586005Free PMC Article
Chan EE, Chow PK
Jpn J Clin Oncol 2017 Apr 1;47(4):287-293. doi: 10.1093/jjco/hyw185. PMID: 27980082
Takahashi Y, Fukusato T
World J Gastroenterol 2014 Nov 14;20(42):15539-48. doi: 10.3748/wjg.v20.i42.15539. PMID: 25400438Free PMC Article

Recent systematic reviews

Sonbol MB, Riaz IB, Naqvi SAA, Almquist DR, Mina S, Almasri J, Shah S, Almader-Douglas D, Uson Junior PLS, Mahipal A, Ma WW, Jin Z, Mody K, Starr J, Borad MJ, Ahn DH, Murad MH, Bekaii-Saab T
JAMA Oncol 2020 Dec 1;6(12):e204930. Epub 2020 Dec 10 doi: 10.1001/jamaoncol.2020.4930. PMID: 33090186Free PMC Article
Stockdale AJ, Kreuels B, Henrion MYR, Giorgi E, Kyomuhangi I, de Martel C, Hutin Y, Geretti AM
J Hepatol 2020 Sep;73(3):523-532. Epub 2020 Apr 23 doi: 10.1016/j.jhep.2020.04.008. PMID: 32335166Free PMC Article
Yang J, Fernández-Galilea M, Martínez-Fernández L, González-Muniesa P, Pérez-Chávez A, Martínez JA, Moreno-Aliaga MJ
Nutrients 2019 Apr 18;11(4) doi: 10.3390/nu11040872. PMID: 31003450Free PMC Article
Tzartzeva K, Obi J, Rich NE, Parikh ND, Marrero JA, Yopp A, Waljee AK, Singal AG
Gastroenterology 2018 May;154(6):1706-1718.e1. Epub 2018 Feb 6 doi: 10.1053/j.gastro.2018.01.064. PMID: 29425931Free PMC Article
Vernon G, Baranova A, Younossi ZM
Aliment Pharmacol Ther 2011 Aug;34(3):274-85. Epub 2011 May 30 doi: 10.1111/j.1365-2036.2011.04724.x. PMID: 21623852

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