Abnormal proportion of double-negative alpha-beta regulatory T cell

MedGen UID:: 1621823
•Concept ID:: C4531150
•: Finding

Synonyms:	Abnormal CD4-negative, CD8-negative, alpha-beta regulatory T cell distribution; Abnormal DN Treg distribution; Abnormal Double negative Treg distribution; Abnormal double-negative alpha-beta regulatory T cell distribution

HPO:	HP:0031399

Definition

An abnormal proportion of CD4-negative, CD8-negative (double negative or DN) alpha-beta regulatory T cells (Tregs) as compared to total number of T cells. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAbnormal proportion of double-negative alpha-beta regulatory T cell

Abnormal cellular immune system morphology
- Abnormal leukocyte morphology
  - Abnormal leukocyte count
    - Abnormal lymphocyte count
      - Abnormal T cell count
        Abnormal T cell subset distribution
        Abnormal proportion of double-negative alpha-beta regulatory T cell
        Elevated proportion of CD4-negative, CD8-negative, alpha-beta regulatory T cells
        Reduced proportion of CD4-negative, CD8-negative, alpha-beta regulatory T cells

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Abnormal proportion of double-negative alpha-beta regulatory T cell

Definition

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