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Metastatic Vulvar Carcinoma

MedGen UID:
1658842
•Concept ID:
C4744545
•
Neoplastic Process

Definition

A carcinoma that arises from the vulva and has metastasized to another anatomic site. [from NCI]

Professional guidelines

PubMed

Extramammary Paget's Disease: Diagnosis, Pathogenesis, and Treatment with Focus on Recent Developments.
Ishizuki S, Nakamura Y
Curr Oncol 2021 Aug 5;28(4):2969-2986. doi: 10.3390/curroncol28040260. PMID: 34436026Free PMC Article
Systemic treatment of vulvar cancer.
Mahner S, Prieske K, Grimm D, Trillsch F, Prieske S, von Amsberg G, Petersen C, Mueller V, Jaenicke F, Woelber L
Expert Rev Anticancer Ther 2015 Jun;15(6):629-37. Epub 2015 May 21 doi: 10.1586/14737140.2015.1037837. PMID: 25997120
FIGO staging for carcinoma of the vulva, cervix, and corpus uteri.
FIGO Committee on Gynecologic Oncology
Int J Gynaecol Obstet 2014 May;125(2):97-8. Epub 2014 Feb 22 doi: 10.1016/j.ijgo.2014.02.003. PMID: 24630859

Recent clinical studies

Etiology

Phase II study on paclitaxel in patients with recurrent, metastatic or locally advanced vulvar cancer not amenable to surgery or radiotherapy: a study of the EORTC-GCG (European Organisation for Research and Treatment of Cancer--Gynaecological Cancer Group).
Witteveen PO, van der Velden J, Vergote I, Guerra C, Scarabeli C, Coens C, Demonty G, Reed N
Ann Oncol 2009 Sep;20(9):1511-1516. Epub 2009 Jun 1 doi: 10.1093/annonc/mdp043. PMID: 19487487Free PMC Article

Diagnosis

HPV16 viral characteristics in primary, recurrent and metastatic vulvar carcinoma.
Lillsunde Larsson G, Kaliff M, Sorbe B, Helenius G, Karlsson MG
Papillomavirus Res 2018 Dec;6:63-69. Epub 2018 Nov 2 doi: 10.1016/j.pvr.2018.10.008. PMID: 30391517Free PMC Article
Multimodal endovascular palliation for femoral arterial blowout in the setting of metastatic vulvar carcinoma.
Nassiri N, Kogan S, Gibbon DG, Graham A
Ann Vasc Surg 2015 Jan;29(1):127.e11-5. Epub 2014 Oct 8 doi: 10.1016/j.avsg.2014.08.012. PMID: 25305425

Therapy

Phase II study on paclitaxel in patients with recurrent, metastatic or locally advanced vulvar cancer not amenable to surgery or radiotherapy: a study of the EORTC-GCG (European Organisation for Research and Treatment of Cancer--Gynaecological Cancer Group).
Witteveen PO, van der Velden J, Vergote I, Guerra C, Scarabeli C, Coens C, Demonty G, Reed N
Ann Oncol 2009 Sep;20(9):1511-1516. Epub 2009 Jun 1 doi: 10.1093/annonc/mdp043. PMID: 19487487Free PMC Article
Recurrent metastatic vulvar carcinoma treated with cisplatin plus cetuximab.
Richard SD, Krivak TC, Beriwal S, Zorn KK
Int J Gynecol Cancer 2008 Sep-Oct;18(5):1132-5. Epub 2007 Nov 16 doi: 10.1111/j.1525-1438.2007.01145.x. PMID: 18021214

Supplemental Content

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