Decreased proportion of CD8-positive, alpha-beta memory T cells

MedGen UID:: 1698626
•Concept ID:: C5139546
•: Finding

HPO:	HP:0410385

Definition

Decreased proportion of CD8-positive, alpha-beta memory T cells compared to the total number of T cells in the blood. A CD8-positive, alpha-beta T cell with memory phenotype is CD45RO and CD127-positive. This cell type is also described as being CD25-negative, CD44-high, and CD122-high. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVDecreased proportion of CD8-positive, alpha-beta memory T cells

Abnormal leukocyte count
- Abnormal lymphocyte count
  - Abnormal T cell count
    - Abnormal T cell subset distribution
      - Abnormal proportion of memory T cells
        Decreased proportion of memory T cells
        Decreased proportion of CD8-positive, alpha-beta memory T cells
        Decreased proportion of CD8-positive, alpha-beta TEMRA T cells
        Decreased proportion of central memory CD8-positive, alpha-beta T cells
        Decreased proportion of effector memory CD8-positive, alpha-beta T cells

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Decreased proportion of CD8-positive, alpha-beta memory T cells

Definition

Term Hierarchy

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