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Cardiac Biphasic Synovial Sarcoma

MedGen UID:
313001
•Concept ID:
C1707293
•
Neoplastic Process
Synonym: Heart Biphasic Synovial Sarcoma

Definition

A biphasic synovial sarcoma arising from the heart. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCardiac Biphasic Synovial Sarcoma

Recent clinical studies

Etiology

Primary cardiac synovial sarcoma: a clinicopathological, immunohistochemical, and molecular genetics study of five clinical cases.
Teng F, Chen D, Li Y, Fang W, Yang S, Shang J, Liu G, Cui Y, Zhao Y, Lian G
Cardiovasc Pathol 2021 Jan-Feb;50:107286. Epub 2020 Sep 16 doi: 10.1016/j.carpath.2020.107286. PMID: 32947039
Primary cardiac synovial sarcoma that was continuous with the mitral valve caused severe thrombocytopenia: a case report.
Zhang G, Gao Q, Chen S, Chen Y
J Cardiothorac Surg 2019 Feb 4;14(1):30. doi: 10.1186/s13019-019-0852-8. PMID: 30717777Free PMC Article

Diagnosis

Right atrial synovial sarcoma with thrombocytopenia: A deceptive presentation.
Shah D, Gupta K, Naik D, Bhavsar N
J Card Surg 2021 Aug;36(8):2992-2995. Epub 2021 May 12 doi: 10.1111/jocs.15631. PMID: 33982302
Delayed PET/CT of Pericardial Synovial Sarcoma.
Stefanelli A, Savelli G, Bonacina M, Zaniboni A
Clin Nucl Med 2021 Sep 1;46(9):e451-e453. doi: 10.1097/RLU.0000000000003603. PMID: 33782303
Primary cardiac synovial sarcoma: a clinicopathological, immunohistochemical, and molecular genetics study of five clinical cases.
Teng F, Chen D, Li Y, Fang W, Yang S, Shang J, Liu G, Cui Y, Zhao Y, Lian G
Cardiovasc Pathol 2021 Jan-Feb;50:107286. Epub 2020 Sep 16 doi: 10.1016/j.carpath.2020.107286. PMID: 32947039
Primary cardiac synovial sarcoma that was continuous with the mitral valve caused severe thrombocytopenia: a case report.
Zhang G, Gao Q, Chen S, Chen Y
J Cardiothorac Surg 2019 Feb 4;14(1):30. doi: 10.1186/s13019-019-0852-8. PMID: 30717777Free PMC Article
Posterior mediastinal biphasic synovial sarcoma in a 12 year-old boy: a case report and review of literature.
Pal M, Ghosh BN, Roy C, Manna AK
J Cancer Res Ther 2010 Oct-Dec;6(4):564-6. doi: 10.4103/0973-1482.77075. PMID: 21358103

Therapy

Synovial sarcoma of the heart: Report of a case with diagnosis by endoscopic ultrasound-guided fine needle aspiration biopsy.
Policarpio-Nicolas ML, Alasadi R, Nayar R, De Frias DV
Acta Cytol 2006 Nov-Dec;50(6):683-6. doi: 10.1159/000326042. PMID: 17152284

Prognosis

Primary cardiac synovial sarcoma: a clinicopathological, immunohistochemical, and molecular genetics study of five clinical cases.
Teng F, Chen D, Li Y, Fang W, Yang S, Shang J, Liu G, Cui Y, Zhao Y, Lian G
Cardiovasc Pathol 2021 Jan-Feb;50:107286. Epub 2020 Sep 16 doi: 10.1016/j.carpath.2020.107286. PMID: 32947039
Primary synovial sarcoma of the right heart involving the tricuspid valve in an elderly Chinese woman: a case report.
Huo Z, Lu H, Mao Q, Jin Z, Wu H, Feng X, Xiao Y, Wang Y, Guo L
Diagn Pathol 2015 Jun 26;10:80. doi: 10.1186/s13000-015-0300-6. PMID: 26112006Free PMC Article
Prox1 transcription factor as a marker for vascular tumors-evaluation of 314 vascular endothelial and 1086 nonvascular tumors.
Miettinen M, Wang ZF
Am J Surg Pathol 2012 Mar;36(3):351-9. doi: 10.1097/PAS.0b013e318236c312. PMID: 22067331Free PMC Article

Clinical prediction guides

Primary cardiac synovial sarcoma: a clinicopathological, immunohistochemical, and molecular genetics study of five clinical cases.
Teng F, Chen D, Li Y, Fang W, Yang S, Shang J, Liu G, Cui Y, Zhao Y, Lian G
Cardiovasc Pathol 2021 Jan-Feb;50:107286. Epub 2020 Sep 16 doi: 10.1016/j.carpath.2020.107286. PMID: 32947039
Primary synovial sarcoma of the right heart involving the tricuspid valve in an elderly Chinese woman: a case report.
Huo Z, Lu H, Mao Q, Jin Z, Wu H, Feng X, Xiao Y, Wang Y, Guo L
Diagn Pathol 2015 Jun 26;10:80. doi: 10.1186/s13000-015-0300-6. PMID: 26112006Free PMC Article
Prox1 transcription factor as a marker for vascular tumors-evaluation of 314 vascular endothelial and 1086 nonvascular tumors.
Miettinen M, Wang ZF
Am J Surg Pathol 2012 Mar;36(3):351-9. doi: 10.1097/PAS.0b013e318236c312. PMID: 22067331Free PMC Article

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