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Salivary Gland Intraductal Carcinoma

MedGen UID:
364329
•Concept ID:
C1882972
•
Neoplastic Process
Synonyms: Low Grade Salivary Duct Carcinoma; Salivary Gland Low Grade Cribriform Cystadenocarcinoma

Definition

A rare, low-grade adenocarcinoma that arises from the salivary glands. It is characterized by the presence of cystic structures lined by ductal cells which are arranged in cribriform patterns. Adjacent ducts show intraductal proliferation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSalivary Gland Intraductal Carcinoma

Professional guidelines

PubMed

Oncocytoid Salivary Tumors: Differential Diagnosis and Utility of Newly Described Immunohistochemistry.
Katabi N
Head Neck Pathol 2024 Mar 19;18(1):20. doi: 10.1007/s12105-024-01622-9. PMID: 38502259Free PMC Article
The Decline of Salivary Adenocarcinoma Not Otherwise Specified as a Tumor Entity: Reclassification Using Contemporary Immunohistochemical Profiling and Diagnostic Criteria.
Rooper LM, Mansour M, Yonescu R, Oliai BR, Bishop JA, Westra WH
Am J Surg Pathol 2021 Jun 1;45(6):753-764. doi: 10.1097/PAS.0000000000001636. PMID: 33284193

Recent clinical studies

Etiology

Salivary Gland Intraductal Carcinoma: How Do 183 Reported Cases Fit Into a Developing Classification.
Thompson LDR, Bishop JA
Adv Anat Pathol 2023 Mar 1;30(2):112-129. Epub 2022 Aug 30 doi: 10.1097/PAP.0000000000000362. PMID: 36040027

Diagnosis

Detection of salivary gland and sinonasal fusions by a next-generation sequencing based, ligation-dependent, multiplex RT-PCR assay.
Lanic MD, Guérin R, Wassef M, Durdilly P, Rainville V, Sater V, Jardin F, Ruminy P, Costes-Martineau V, Laé M
Histopathology 2023 Nov;83(5):685-699. Epub 2023 Jun 22 doi: 10.1111/his.14971. PMID: 37350081
Salivary Gland Intraductal Carcinoma: How Do 183 Reported Cases Fit Into a Developing Classification.
Thompson LDR, Bishop JA
Adv Anat Pathol 2023 Mar 1;30(2):112-129. Epub 2022 Aug 30 doi: 10.1097/PAP.0000000000000362. PMID: 36040027
Oncocytic intraductal carcinoma of salivary glands: a distinct variant with TRIM33-RET fusions and BRAF V600E mutations.
Bishop JA, Nakaguro M, Whaley RD, Ogura K, Imai H, Laklouk I, Faquin WC, Sadow PM, Gagan J, Nagao T
Histopathology 2021 Sep;79(3):338-346. Epub 2021 Mar 31 doi: 10.1111/his.14296. PMID: 33135196Free PMC Article
Intraductal Carcinoma of Salivary Gland Originating from an Intraparotid Lymph Node: A Case Report.
Lin SC, Ko RT, Kang BH, Wang JS
Malays J Pathol 2019 Aug;41(2):207-211. PMID: 31427558

Prognosis

Intraductal Carcinoma of Salivary Gland Originating from an Intraparotid Lymph Node: A Case Report.
Lin SC, Ko RT, Kang BH, Wang JS
Malays J Pathol 2019 Aug;41(2):207-211. PMID: 31427558

Clinical prediction guides

Salivary Gland Intraductal Carcinoma: How Do 183 Reported Cases Fit Into a Developing Classification.
Thompson LDR, Bishop JA
Adv Anat Pathol 2023 Mar 1;30(2):112-129. Epub 2022 Aug 30 doi: 10.1097/PAP.0000000000000362. PMID: 36040027

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