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Primary hypophysitis

MedGen UID:
575013
Concept ID:
C0342410
Disease or Syndrome
Synonyms: Autoimmune Hypophysitides; Autoimmune Hypophysitis; Hypophysitides, Autoimmune; Hypophysitides, Lymphocytic; Hypophysitides, Lymphoid; Hypophysitis, Autoimmune; Hypophysitis, Lymphocytic; Hypophysitis, Lymphoid; Lymphocytic Hypophysitides; Lymphocytic Hypophysitis; Lymphoid Hypophysitides; Lymphoid Hypophysitis
SNOMED CT: Autoimmune hypophysitis (237706000)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0019835
Orphanet: ORPHA95506

Definition

An autoimmune condition affecting the pituitary gland, characterized by lymphocytic infiltration, commonly presenting with pituitary hormone deficiencies. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Atkins P, Ur E
Endocr Res 2020 Nov;45(4):246-253. Epub 2020 Sep 5 doi: 10.1080/07435800.2020.1817064. PMID: 32892666
Kluczyński Ł, Gilis-Januszewska A, Rogoziński D, Pantofliński J, Hubalewska-Dydejczyk A
Endokrynol Pol 2019;70(3):260-269. doi: 10.5603/EP.a2019.0015. PMID: 31290557
Joshi MN, Whitelaw BC, Carroll PV
Eur J Endocrinol 2018 Sep;179(3):R151-R163. Epub 2018 Jun 7 doi: 10.1530/EJE-17-0009. PMID: 29880706

Recent clinical studies

Etiology

Vakharia JD, Muhammed M, Remba-Shapiro I, Marsiglia M, Hadaway N, Chwalisz BK, Nachtigall LB
Eur J Endocrinol 2023 Sep 1;189(3):309-317. doi: 10.1093/ejendo/lvad115. PMID: 37602514Free PMC Article
Chatterjee S, Chatterjee S, Bhartiya S
Neurol India 2023 Jan-Feb;71(1):119-121. doi: 10.4103/0028-3886.370481. PMID: 36861584
Amereller F, Deutschbein T, Joshi M, Schopohl J, Schilbach K, Detomas M, Duffy L, Carroll P, Papa S, Störmann S
Pituitary 2022 Feb;25(1):152-158. Epub 2021 Sep 13 doi: 10.1007/s11102-021-01182-z. PMID: 34518996Free PMC Article
Atkins P, Ur E
Endocr Res 2020 Nov;45(4):246-253. Epub 2020 Sep 5 doi: 10.1080/07435800.2020.1817064. PMID: 32892666
Karaca Z, Kelestimur F
Minerva Endocrinol 2016 Sep;41(3):390-9. Epub 2016 Mar 10 PMID: 26963662

Diagnosis

Gubbi S, Hannah-Shmouni F, Stratakis CA, Koch CA
Rev Endocr Metab Disord 2018 Dec;19(4):335-347. doi: 10.1007/s11154-018-9480-1. PMID: 30547288
Joshi MN, Whitelaw BC, Carroll PV
Eur J Endocrinol 2018 Sep;179(3):R151-R163. Epub 2018 Jun 7 doi: 10.1530/EJE-17-0009. PMID: 29880706
Allix I, Rohmer V
Ann Endocrinol (Paris) 2015 Oct;76(5):585-94. Epub 2015 Oct 26 doi: 10.1016/j.ando.2015.08.003. PMID: 26514950
Hanna B, Li YM, Beutler T, Goyal P, Hall WA
J Clin Neurosci 2015 Jul;22(7):1091-7. Epub 2015 May 6 doi: 10.1016/j.jocn.2015.01.019. PMID: 25957783
Fukuoka H
Endocrinol Metab Clin North Am 2015 Mar;44(1):143-9. Epub 2014 Nov 4 doi: 10.1016/j.ecl.2014.10.011. PMID: 25732650

Therapy

Amereller F, Deutschbein T, Joshi M, Schopohl J, Schilbach K, Detomas M, Duffy L, Carroll P, Papa S, Störmann S
Pituitary 2022 Feb;25(1):152-158. Epub 2021 Sep 13 doi: 10.1007/s11102-021-01182-z. PMID: 34518996Free PMC Article
Krishnappa B, Shah R, Sarathi V, Lila AR, Sehemby MK, Patil VA, Sankhe S, Shah N, Bandgar T
Neuroendocrinology 2022;112(2):186-195. Epub 2021 Mar 19 doi: 10.1159/000516006. PMID: 33744880
Karaca Z, Kelestimur F
Minerva Endocrinol 2016 Sep;41(3):390-9. Epub 2016 Mar 10 PMID: 26963662
Allix I, Rohmer V
Ann Endocrinol (Paris) 2015 Oct;76(5):585-94. Epub 2015 Oct 26 doi: 10.1016/j.ando.2015.08.003. PMID: 26514950
Hanna B, Li YM, Beutler T, Goyal P, Hall WA
J Clin Neurosci 2015 Jul;22(7):1091-7. Epub 2015 May 6 doi: 10.1016/j.jocn.2015.01.019. PMID: 25957783

Prognosis

Krishnappa B, Shah R, Sarathi V, Lila AR, Sehemby MK, Patil VA, Sankhe S, Shah N, Bandgar T
Neuroendocrinology 2022;112(2):186-195. Epub 2021 Mar 19 doi: 10.1159/000516006. PMID: 33744880
Zhu J, Wang Z, Wang W, Fan J, Zhang Y, Li X, Liu J, Jiang S, Deng K, Duan L, Yao Y, Zhu H
Front Endocrinol (Lausanne) 2021;12:735655. Epub 2021 Oct 1 doi: 10.3389/fendo.2021.735655. PMID: 34659121Free PMC Article
Oguz SH, Soylemezoglu F, Sendur SN, Mut M, Oguz KK, Dagdelen S, Erbas T
Horm Metab Res 2020 Apr;52(4):220-227. Epub 2020 Apr 8 doi: 10.1055/a-1113-7777. PMID: 32268423
Kluczyński Ł, Gilis-Januszewska A, Rogoziński D, Pantofliński J, Hubalewska-Dydejczyk A
Endokrynol Pol 2019;70(3):260-269. doi: 10.5603/EP.a2019.0015. PMID: 31290557
Fukuoka H
Endocrinol Metab Clin North Am 2015 Mar;44(1):143-9. Epub 2014 Nov 4 doi: 10.1016/j.ecl.2014.10.011. PMID: 25732650

Clinical prediction guides

Amereller F, Küppers AM, Schilbach K, Schopohl J, Störmann S
Exp Clin Endocrinol Diabetes 2021 Mar;129(3):234-240. Epub 2020 Aug 7 doi: 10.1055/a-1163-7304. PMID: 32770534
Atkins P, Ur E
Endocr Res 2020 Nov;45(4):246-253. Epub 2020 Sep 5 doi: 10.1080/07435800.2020.1817064. PMID: 32892666
Oguz SH, Soylemezoglu F, Sendur SN, Mut M, Oguz KK, Dagdelen S, Erbas T
Horm Metab Res 2020 Apr;52(4):220-227. Epub 2020 Apr 8 doi: 10.1055/a-1113-7777. PMID: 32268423
Angelousi A, Cohen C, Sosa S, Danilowicz K, Papanastasiou L, Tsoli M, Pal A, Piaditis G, Grossman A, Kaltsas G
Horm Metab Res 2018 Apr;50(4):296-302. Epub 2018 Feb 19 doi: 10.1055/s-0044-101036. PMID: 29458219
Karaca Z, Kelestimur F
Minerva Endocrinol 2016 Sep;41(3):390-9. Epub 2016 Mar 10 PMID: 26963662

Recent systematic reviews

Zhu J, Wang Z, Wang W, Fan J, Zhang Y, Li X, Liu J, Jiang S, Deng K, Duan L, Yao Y, Zhu H
Front Endocrinol (Lausanne) 2021;12:735655. Epub 2021 Oct 1 doi: 10.3389/fendo.2021.735655. PMID: 34659121Free PMC Article

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