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Cranial nerve neuropathy

MedGen UID:
1160
•Concept ID:
C0010266
•
Disease or Syndrome
Synonyms: Cranial Nerve Disease; Cranial Nerve Diseases; Cranial Nerve Disorder; Cranial Nerve Disorders; Cranial Neuropathies; Cranial Neuropathy; Nervus Cranialis Disorder; Nervus Cranialis Disorders; Neuropathies, Cranial; Neuropathy, Cranial
SNOMED CT: Cranial nerve disorder (73013002); Cranial neuropathy (73013002); Disorder of cranial nerve (73013002)
 
Monarch Initiative: MONDO:0003569

Definition

A neoplastic or non-neoplastic disorder that affects one of the cranial nerves. [from NCI]

Professional guidelines

PubMed

Management and long-term comorbidities of patients with necrotizing otitis externa.
Arslan IB, Pekcevik Y, Cukurova I
Eur Arch Otorhinolaryngol 2023 Jun;280(6):2755-2761. Epub 2022 Dec 18 doi: 10.1007/s00405-022-07784-y. PMID: 36528642Free PMC Article
Radiotherapy in the treatment of benign meningioma of the skull base.
Nutting C, Brada M, Brazil L, Sibtain A, Saran F, Westbury C, Moore A, Thomas DG, Traish D, Ashley S
J Neurosurg 1999 May;90(5):823-7. doi: 10.3171/jns.1999.90.5.0823. PMID: 10223446

Recent clinical studies

Etiology

Prevalence of and risk factors for cranial neuropathy in diabetic and non-diabetic patients.
AlZailaie AK, Aseeri AM, Algahtany AM, Algahtany MM, Algahtany MA
Eur Rev Med Pharmacol Sci 2023 Jun;27(11):4990-4997. doi: 10.26355/eurrev_202306_32616. PMID: 37318473
COVID-19 associated cranial nerve neuropathy: A systematic review.
Finsterer J, Scorza FA, Scorza C, Fiorini A
Bosn J Basic Med Sci 2022 Feb 1;22(1):39-45. doi: 10.17305/bjbms.2021.6341. PMID: 34392827Free PMC Article
Neurological impact of eosinophilic granulomatosis with polyangiitis.
Gomes I, Girão A, Gomes J, Rebelo O, Jesus-Ribeiro J
Acta Neurol Belg 2022 Feb;122(1):123-128. Epub 2021 Apr 27 doi: 10.1007/s13760-021-01683-5. PMID: 33905106
Pembrolizumab Monotherapy for Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma: A Single-Arm Phase II Trial (KEYNOTE-629).
Grob JJ, Gonzalez R, Basset-Seguin N, Vornicova O, Schachter J, Joshi A, Meyer N, Grange F, Piulats JM, Bauman JR, Zhang P, Gumuscu B, Swaby RF, Hughes BGM
J Clin Oncol 2020 Sep 1;38(25):2916-2925. Epub 2020 Jul 16 doi: 10.1200/JCO.19.03054. PMID: 32673170Free PMC Article
Parapharyngeal space neoplasms.
Hughes KV 3rd, Olsen KD, McCaffrey TV
Head Neck 1995 Mar-Apr;17(2):124-30. doi: 10.1002/hed.2880170209. PMID: 7558809

Diagnosis

COVID-19 associated cranial nerve neuropathy: A systematic review.
Finsterer J, Scorza FA, Scorza C, Fiorini A
Bosn J Basic Med Sci 2022 Feb 1;22(1):39-45. doi: 10.17305/bjbms.2021.6341. PMID: 34392827Free PMC Article
Neurological impact of eosinophilic granulomatosis with polyangiitis.
Gomes I, Girão A, Gomes J, Rebelo O, Jesus-Ribeiro J
Acta Neurol Belg 2022 Feb;122(1):123-128. Epub 2021 Apr 27 doi: 10.1007/s13760-021-01683-5. PMID: 33905106
Relapsing Painful Ophthalmoplegic Neuropathy: No longer a "Migraine," but Still a Headache.
Smith SV, Schuster NM
Curr Pain Headache Rep 2018 Jun 14;22(7):50. doi: 10.1007/s11916-018-0705-5. PMID: 29904898
Gustatory rhinitis.
Jovancevic L, Georgalas C, Savovic S, Janjevic D
Rhinology 2010 Mar 2;48(1):7-10. doi: 10.4193/Rhin07.153. PMID: 20502728
Parapharyngeal space neoplasms.
Hughes KV 3rd, Olsen KD, McCaffrey TV
Head Neck 1995 Mar-Apr;17(2):124-30. doi: 10.1002/hed.2880170209. PMID: 7558809

Therapy

Prevalence of and risk factors for cranial neuropathy in diabetic and non-diabetic patients.
AlZailaie AK, Aseeri AM, Algahtany AM, Algahtany MM, Algahtany MA
Eur Rev Med Pharmacol Sci 2023 Jun;27(11):4990-4997. doi: 10.26355/eurrev_202306_32616. PMID: 37318473
Recurrent Painful Ophthalmoplegic Neuropathy with Unilateral Oculomotor and Trochlear Nerve Palsy in an 8-year-old Girl.
Akhondian J, Ashrafzadeh F, Seilanian Toosi F, Esmaeilzadeh M, Beiraghi Toosi M, Imannezhad S, Saeedi Zand N, Hashemi N
J Binocul Vis Ocul Motil 2022 Oct-Dec;72(4):199-204. Epub 2022 Jul 22 PMID: 35867412
Pembrolizumab Monotherapy for Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma: A Single-Arm Phase II Trial (KEYNOTE-629).
Grob JJ, Gonzalez R, Basset-Seguin N, Vornicova O, Schachter J, Joshi A, Meyer N, Grange F, Piulats JM, Bauman JR, Zhang P, Gumuscu B, Swaby RF, Hughes BGM
J Clin Oncol 2020 Sep 1;38(25):2916-2925. Epub 2020 Jul 16 doi: 10.1200/JCO.19.03054. PMID: 32673170Free PMC Article
Single fraction versus fractionated linac-based stereotactic radiotherapy for vestibular schwannoma: a single-institution experience.
Collen C, Ampe B, Gevaert T, Moens M, Linthout N, De Ridder M, Verellen D, D'Haens J, Storme G
Int J Radiat Oncol Biol Phys 2011 Nov 15;81(4):e503-9. Epub 2011 Jun 12 doi: 10.1016/j.ijrobp.2011.04.066. PMID: 21665381
The usefulness of the blink reflex in the early diagnosis of cranial nerve neuropathy associated with diabetes mellitus.
Al-Azzawi LM, Mirza Kb, Kummoona R
Electromyogr Clin Neurophysiol 2004 Sep;44(6):323-7. PMID: 15473343

Prognosis

Recurrent Painful Ophthalmoplegic Neuropathy and Oculomotor Nerve Schwannoma: A Pediatric Case Report with Long-Term MRI Follow-Up and Literature Review.
Petruzzelli MG, Margari M, Furente F, Costanza MC, Legrottaglie AR, Dicuonzo F, Margari L
Pain Res Manag 2019;2019:5392945. Epub 2019 Sep 25 doi: 10.1155/2019/5392945. PMID: 31662812Free PMC Article
Relapsing Painful Ophthalmoplegic Neuropathy: No longer a "Migraine," but Still a Headache.
Smith SV, Schuster NM
Curr Pain Headache Rep 2018 Jun 14;22(7):50. doi: 10.1007/s11916-018-0705-5. PMID: 29904898
Single fraction versus fractionated linac-based stereotactic radiotherapy for vestibular schwannoma: a single-institution experience.
Collen C, Ampe B, Gevaert T, Moens M, Linthout N, De Ridder M, Verellen D, D'Haens J, Storme G
Int J Radiat Oncol Biol Phys 2011 Nov 15;81(4):e503-9. Epub 2011 Jun 12 doi: 10.1016/j.ijrobp.2011.04.066. PMID: 21665381
Otogenic cranial base osteomyelitis: a proposed prognosis-based system for disease classification.
Lee S, Hooper R, Fuller A, Turlakow A, Cousins V, Nouraei R
Otol Neurotol 2008 Aug;29(5):666-72. doi: 10.1097/MAO.0b013e318179972f. PMID: 18520626
Parapharyngeal space neoplasms.
Hughes KV 3rd, Olsen KD, McCaffrey TV
Head Neck 1995 Mar-Apr;17(2):124-30. doi: 10.1002/hed.2880170209. PMID: 7558809

Clinical prediction guides

Management and long-term comorbidities of patients with necrotizing otitis externa.
Arslan IB, Pekcevik Y, Cukurova I
Eur Arch Otorhinolaryngol 2023 Jun;280(6):2755-2761. Epub 2022 Dec 18 doi: 10.1007/s00405-022-07784-y. PMID: 36528642Free PMC Article
3D aneurysm wall enhancement is associated with symptomatic presentation.
Raghuram A, Sanchez S, Wendt L, Cochran S, Ishii D, Osorno C, Bathla G, Koscik TR, Torner J, Hasan D, Samaniego EA
J Neurointerv Surg 2023 Aug;15(8):747-752. Epub 2022 Jul 19 doi: 10.1136/jnis-2022-019125. PMID: 35853699Free PMC Article
Neurological impact of eosinophilic granulomatosis with polyangiitis.
Gomes I, Girão A, Gomes J, Rebelo O, Jesus-Ribeiro J
Acta Neurol Belg 2022 Feb;122(1):123-128. Epub 2021 Apr 27 doi: 10.1007/s13760-021-01683-5. PMID: 33905106
Single fraction versus fractionated linac-based stereotactic radiotherapy for vestibular schwannoma: a single-institution experience.
Collen C, Ampe B, Gevaert T, Moens M, Linthout N, De Ridder M, Verellen D, D'Haens J, Storme G
Int J Radiat Oncol Biol Phys 2011 Nov 15;81(4):e503-9. Epub 2011 Jun 12 doi: 10.1016/j.ijrobp.2011.04.066. PMID: 21665381
Gustatory rhinitis.
Jovancevic L, Georgalas C, Savovic S, Janjevic D
Rhinology 2010 Mar 2;48(1):7-10. doi: 10.4193/Rhin07.153. PMID: 20502728

Recent systematic reviews

COVID-19 associated cranial nerve neuropathy: A systematic review.
Finsterer J, Scorza FA, Scorza C, Fiorini A
Bosn J Basic Med Sci 2022 Feb 1;22(1):39-45. doi: 10.17305/bjbms.2021.6341. PMID: 34392827Free PMC Article
Stereotactic Radiosurgery in Large Intracranial Meningiomas: A Systematic Review.
Fatima N, Meola A, Pollom E, Chaudhary N, Soltys S, Chang SD
World Neurosurg 2019 Sep;129:269-275. Epub 2019 Jun 19 doi: 10.1016/j.wneu.2019.06.064. PMID: 31226450

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