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Microvascular complications of diabetes, susceptibility to, 7(MVCD7)

MedGen UID:
382123
•Concept ID:
C2673520
•
Finding
Synonym: Microvascular complications of diabetes 7
 
Monarch Initiative: MONDO:0012971
OMIM®: 612635

Definition

Any microvascular complications of diabetes, susceptibility in which the cause of the disease is a mutation in the HFE gene. [from MONDO]

Professional guidelines

PubMed

Diabetes mellitus: novel insights, analysis and interpretation of pathophysiology and complications management with imidazole-containing peptidomimetic antioxidants.
Babizhayev MA, Lankin VZ, Savel'Yeva EL, Deyev AI, Yegorov YE
Recent Pat Drug Deliv Formul 2013 Dec;7(3):216-56. doi: 10.2174/1872211307666131117121058. PMID: 24236935
Report of the Committee on the classification and diagnostic criteria of diabetes mellitus.
Kuzuya T, Nakagawa S, Satoh J, Kanazawa Y, Iwamoto Y, Kobayashi M, Nanjo K, Sasaki A, Seino Y, Ito C, Shima K, Nonaka K, Kadowaki T; Committee of the Japan Diabetes Society on the diagnostic criteria of diabetes mellitus
Diabetes Res Clin Pract 2002 Jan;55(1):65-85. doi: 10.1016/s0168-8227(01)00365-5. PMID: 11755481

Recent clinical studies

Etiology

Genetic risk score is associated with T2DM and diabetes complications risks.
Hubacek JA, Dlouha L, Adamkova V, Dlouha D, Pacal L, Kankova K, Galuska D, Lanska V, Veleba J, Pelikanova T
Gene 2023 Jan 15;849:146921. Epub 2022 Sep 26 doi: 10.1016/j.gene.2022.146921. PMID: 36174902
Do Long-Term Complications of Type 2 Diabetes Increase Susceptibility to Geriatric Syndromes in Older Adults?
Çakmak G, Ganidağlı S, Efendioğlu EM, Öztürk E, Öztürk ZA
Medicina (Kaunas) 2021 Sep 15;57(9) doi: 10.3390/medicina57090968. PMID: 34577891Free PMC Article
TCF7L2 gene polymorphism as a risk for type 2 diabetes mellitus and diabetic microvascular complications.
Aboelkhair NT, Kasem HE, Abdelmoaty AA, El-Edel RH
Mol Biol Rep 2021 Jun;48(6):5283-5290. Epub 2021 Jul 7 doi: 10.1007/s11033-021-06537-0. PMID: 34232465
Associations of TP53 codon 72 polymorphism with complications and comorbidities in patients with type 1 diabetes.
Słomiński B, Skrzypkowska M, Ryba-Stanisławowska M, Myśliwiec M, Trzonkowski P
J Mol Med (Berl) 2021 May;99(5):675-683. Epub 2021 Jan 25 doi: 10.1007/s00109-020-02035-1. PMID: 33495869Free PMC Article
Microvascular Disease, Peripheral Artery Disease, and Amputation.
Beckman JA, Duncan MS, Damrauer SM, Wells QS, Barnett JV, Wasserman DH, Bedimo RJ, Butt AA, Marconi VC, Sico JJ, Tindle HA, Bonaca MP, Aday AW, Freiberg MS
Circulation 2019 Aug 6;140(6):449-458. Epub 2019 Jul 8 doi: 10.1161/CIRCULATIONAHA.119.040672. PMID: 31280589Free PMC Article

Diagnosis

Relationship between circulating metabolites and diabetic retinopathy: a two-sample Mendelian randomization analysis.
Ma L, Dong Y, Li Z, Meng J, Zhao B, Wang Q
Sci Rep 2024 Feb 29;14(1):4964. doi: 10.1038/s41598-024-55704-3. PMID: 38424453Free PMC Article
Microvascular and macrovascular complications of type 2 diabetes mellitus: Exome wide association analyses.
Mansour A, Mousa M, Abdelmannan D, Tay G, Hassoun A, Alsafar H
Front Endocrinol (Lausanne) 2023;14:1143067. Epub 2023 Mar 23 doi: 10.3389/fendo.2023.1143067. PMID: 37033211Free PMC Article
Do Long-Term Complications of Type 2 Diabetes Increase Susceptibility to Geriatric Syndromes in Older Adults?
Çakmak G, Ganidağlı S, Efendioğlu EM, Öztürk E, Öztürk ZA
Medicina (Kaunas) 2021 Sep 15;57(9) doi: 10.3390/medicina57090968. PMID: 34577891Free PMC Article
Young-onset type 2 diabetes and younger current age: increased susceptibility to retinopathy in contrast to other complications.
Middleton TL, Constantino MI, Molyneaux L, D'Souza M, Twigg SM, Wu T, Yue DK, Zoungas S, Wong J
Diabet Med 2020 Jun;37(6):991-999. Epub 2020 Feb 5 doi: 10.1111/dme.14238. PMID: 31968129Free PMC Article
Microvascular Disease, Peripheral Artery Disease, and Amputation.
Beckman JA, Duncan MS, Damrauer SM, Wells QS, Barnett JV, Wasserman DH, Bedimo RJ, Butt AA, Marconi VC, Sico JJ, Tindle HA, Bonaca MP, Aday AW, Freiberg MS
Circulation 2019 Aug 6;140(6):449-458. Epub 2019 Jul 8 doi: 10.1161/CIRCULATIONAHA.119.040672. PMID: 31280589Free PMC Article

Therapy

Relationship between circulating metabolites and diabetic retinopathy: a two-sample Mendelian randomization analysis.
Ma L, Dong Y, Li Z, Meng J, Zhao B, Wang Q
Sci Rep 2024 Feb 29;14(1):4964. doi: 10.1038/s41598-024-55704-3. PMID: 38424453Free PMC Article
Associations between the polymorphisms of main components in PI3K/Akt pathway and risk of diabetic kidney disease: A meta-analysis.
Fu H, Guo C, Zhang J, Xu L, Jiang S, Guo S, Sheng Q, Zhao J, Liao L
IUBMB Life 2023 Jul;75(7):624-642. Epub 2023 Mar 1 doi: 10.1002/iub.2711. PMID: 36856001
Investigation of angiotensin-1 converting enzyme 2 gene (G8790A) polymorphism in patients of type 2 diabetes mellitus with diabetic nephropathy in Pakistani population.
Younas H, Ijaz T, Choudhry N
PLoS One 2022;17(2):e0264038. Epub 2022 Feb 17 doi: 10.1371/journal.pone.0264038. PMID: 35176079Free PMC Article
Diabetes mellitus: novel insights, analysis and interpretation of pathophysiology and complications management with imidazole-containing peptidomimetic antioxidants.
Babizhayev MA, Lankin VZ, Savel'Yeva EL, Deyev AI, Yegorov YE
Recent Pat Drug Deliv Formul 2013 Dec;7(3):216-56. doi: 10.2174/1872211307666131117121058. PMID: 24236935
Chromosome 7q35 and susceptibility to diabetic microvascular complications.
Patel A, Hibberd ML, Millward BA, Demaine AG
J Diabetes Complications 1996 Mar-Apr;10(2):62-7. doi: 10.1016/1056-8727(95)00004-6. PMID: 8777332

Prognosis

Relationship between circulating metabolites and diabetic retinopathy: a two-sample Mendelian randomization analysis.
Ma L, Dong Y, Li Z, Meng J, Zhao B, Wang Q
Sci Rep 2024 Feb 29;14(1):4964. doi: 10.1038/s41598-024-55704-3. PMID: 38424453Free PMC Article
Genetic risk score is associated with T2DM and diabetes complications risks.
Hubacek JA, Dlouha L, Adamkova V, Dlouha D, Pacal L, Kankova K, Galuska D, Lanska V, Veleba J, Pelikanova T
Gene 2023 Jan 15;849:146921. Epub 2022 Sep 26 doi: 10.1016/j.gene.2022.146921. PMID: 36174902
Associations of TP53 codon 72 polymorphism with complications and comorbidities in patients with type 1 diabetes.
Słomiński B, Skrzypkowska M, Ryba-Stanisławowska M, Myśliwiec M, Trzonkowski P
J Mol Med (Berl) 2021 May;99(5):675-683. Epub 2021 Jan 25 doi: 10.1007/s00109-020-02035-1. PMID: 33495869Free PMC Article
Systematic Genetic Study of Youth With Diabetes in a Single Country Reveals the Prevalence of Diabetes Subtypes, Novel Candidate Genes, and Response to Precision Therapy.
Stankute I, Verkauskiene R, Blouin JL, Klee P, Dobrovolskiene R, Danyte E, Dirlewanger M, Santoni F, Razanskaite-Virbickiene D, Marciulionyte D, Jasinskiene E, Mockeviciene G, Schwitzgebel VM
Diabetes 2020 May;69(5):1065-1071. Epub 2020 Feb 21 doi: 10.2337/db19-0974. PMID: 32086287
Microvascular Disease, Peripheral Artery Disease, and Amputation.
Beckman JA, Duncan MS, Damrauer SM, Wells QS, Barnett JV, Wasserman DH, Bedimo RJ, Butt AA, Marconi VC, Sico JJ, Tindle HA, Bonaca MP, Aday AW, Freiberg MS
Circulation 2019 Aug 6;140(6):449-458. Epub 2019 Jul 8 doi: 10.1161/CIRCULATIONAHA.119.040672. PMID: 31280589Free PMC Article

Clinical prediction guides

Relationship between circulating metabolites and diabetic retinopathy: a two-sample Mendelian randomization analysis.
Ma L, Dong Y, Li Z, Meng J, Zhao B, Wang Q
Sci Rep 2024 Feb 29;14(1):4964. doi: 10.1038/s41598-024-55704-3. PMID: 38424453Free PMC Article
Genetic risk score is associated with T2DM and diabetes complications risks.
Hubacek JA, Dlouha L, Adamkova V, Dlouha D, Pacal L, Kankova K, Galuska D, Lanska V, Veleba J, Pelikanova T
Gene 2023 Jan 15;849:146921. Epub 2022 Sep 26 doi: 10.1016/j.gene.2022.146921. PMID: 36174902
Do Long-Term Complications of Type 2 Diabetes Increase Susceptibility to Geriatric Syndromes in Older Adults?
Çakmak G, Ganidağlı S, Efendioğlu EM, Öztürk E, Öztürk ZA
Medicina (Kaunas) 2021 Sep 15;57(9) doi: 10.3390/medicina57090968. PMID: 34577891Free PMC Article
Association of Combined TCF7L2 and KCNQ1 Gene Polymorphisms with Diabetic Micro- and Macrovascular Complications in Type 2 Diabetes Mellitus.
Rattanatham R, Settasatian N, Komanasin N, Kukongviriyapan U, Sawanyawisuth K, Intharaphet P, Senthong V, Settasatian C
Diabetes Metab J 2021 Jul;45(4):578-593. Epub 2021 Mar 22 doi: 10.4093/dmj.2020.0101. PMID: 33752320Free PMC Article
Associations of TP53 codon 72 polymorphism with complications and comorbidities in patients with type 1 diabetes.
Słomiński B, Skrzypkowska M, Ryba-Stanisławowska M, Myśliwiec M, Trzonkowski P
J Mol Med (Berl) 2021 May;99(5):675-683. Epub 2021 Jan 25 doi: 10.1007/s00109-020-02035-1. PMID: 33495869Free PMC Article

Recent systematic reviews

(Ultra-)long-acting insulin analogues versus NPH insulin (human isophane insulin) for adults with type 2 diabetes mellitus.
Semlitsch T, Engler J, Siebenhofer A, Jeitler K, Berghold A, Horvath K
Cochrane Database Syst Rev 2020 Nov 9;11(11):CD005613. doi: 10.1002/14651858.CD005613.pub4. PMID: 33166419Free PMC Article

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