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Microvascular complications of diabetes, protection against

MedGen UID:
866266
•Concept ID:
C4017829
•
Finding
Synonym: Microvascular complications of diabetes, protection from
 
OMIM®: 603933

Professional guidelines

PubMed

Diabetes pathogenesis and management: the endothelium comes of age.
Love KM, Barrett EJ, Malin SK, Reusch JEB, Regensteiner JG, Liu Z
J Mol Cell Biol 2021 Oct 21;13(7):500-512. doi: 10.1093/jmcb/mjab024. PMID: 33787922Free PMC Article
Pharmacological treatment of hyperglycemia in type 2 diabetes.
Taylor SI, Yazdi ZS, Beitelshees AL
J Clin Invest 2021 Jan 19;131(2) doi: 10.1172/JCI142243. PMID: 33463546Free PMC Article
Prevention and treatment of diabetic retinopathy: evidence from clinical trials and perspectives.
Abbate M, Cravedi P, Iliev I, Remuzzi G, Ruggenenti P
Curr Diabetes Rev 2011 May;7(3):190-200. doi: 10.2174/157339911795843168. PMID: 21438851

Recent clinical studies

Etiology

Incretins and microvascular complications of diabetes: neuropathy, nephropathy, retinopathy and microangiopathy.
Goldney J, Sargeant JA, Davies MJ
Diabetologia 2023 Oct;66(10):1832-1845. Epub 2023 Aug 19 doi: 10.1007/s00125-023-05988-3. PMID: 37597048Free PMC Article
Genetics of diabetes-associated microvascular complications.
Lyssenko V, Vaag A
Diabetologia 2023 Sep;66(9):1601-1613. Epub 2023 Jul 14 doi: 10.1007/s00125-023-05964-x. PMID: 37452207Free PMC Article
Dietary Intake and Diabetic Retinopathy: A Systematic Review of the Literature.
Shah J, Cheong ZY, Tan B, Wong D, Liu X, Chua J
Nutrients 2022 Nov 25;14(23) doi: 10.3390/nu14235021. PMID: 36501054Free PMC Article
Pharmacological treatment of hyperglycemia in type 2 diabetes.
Taylor SI, Yazdi ZS, Beitelshees AL
J Clin Invest 2021 Jan 19;131(2) doi: 10.1172/JCI142243. PMID: 33463546Free PMC Article
Microvascular complications in diabetes: A growing concern for cardiologists.
Avogaro A, Fadini GP
Int J Cardiol 2019 Sep 15;291:29-35. Epub 2019 Feb 25 doi: 10.1016/j.ijcard.2019.02.030. PMID: 30833106

Diagnosis

Microvascular complications in diabetes: A growing concern for cardiologists.
Avogaro A, Fadini GP
Int J Cardiol 2019 Sep 15;291:29-35. Epub 2019 Feb 25 doi: 10.1016/j.ijcard.2019.02.030. PMID: 30833106
Ginsenoside Rb1 as an Anti-Diabetic Agent and Its Underlying Mechanism Analysis.
Zhou P, Xie W, He S, Sun Y, Meng X, Sun G, Sun X
Cells 2019 Feb 28;8(3) doi: 10.3390/cells8030204. PMID: 30823412Free PMC Article
Histopathological changes in major amputations due to diabetic foot - a review.
Gherman D, Dumitrescu CI, Ciocan A, Melincovici CS
Rom J Morphol Embryol 2018;59(3):699-702. PMID: 30534807
The protean role of haptoglobin and haptoglobin genotypes on vascular complications in diabetes mellitus.
Dalan R, Liuh Ling G
Eur J Prev Cardiol 2018 Sep;25(14):1502-1519. Epub 2018 May 25 doi: 10.1177/2047487318776829. PMID: 29799294
Glucose lowering and cardiovascular disease: what do we know and what should we do?
Cheng AY, Leiter LA
Eur J Cardiovasc Prev Rehabil 2010 May;17 Suppl 1:S25-31. doi: 10.1097/01.hjr.0000368194.32356.5f. PMID: 20489417

Therapy

Incretins and microvascular complications of diabetes: neuropathy, nephropathy, retinopathy and microangiopathy.
Goldney J, Sargeant JA, Davies MJ
Diabetologia 2023 Oct;66(10):1832-1845. Epub 2023 Aug 19 doi: 10.1007/s00125-023-05988-3. PMID: 37597048Free PMC Article
Targeted pharmacotherapy against neurodegeneration and neuroinflammation in early diabetic retinopathy.
Rolev KD, Shu XS, Ying Y
Neuropharmacology 2021 Apr 1;187:108498. Epub 2021 Feb 12 doi: 10.1016/j.neuropharm.2021.108498. PMID: 33582150
Pharmacological treatment of hyperglycemia in type 2 diabetes.
Taylor SI, Yazdi ZS, Beitelshees AL
J Clin Invest 2021 Jan 19;131(2) doi: 10.1172/JCI142243. PMID: 33463546Free PMC Article
Microvascular complications in diabetes: A growing concern for cardiologists.
Avogaro A, Fadini GP
Int J Cardiol 2019 Sep 15;291:29-35. Epub 2019 Feb 25 doi: 10.1016/j.ijcard.2019.02.030. PMID: 30833106
Ginsenoside Rb1 as an Anti-Diabetic Agent and Its Underlying Mechanism Analysis.
Zhou P, Xie W, He S, Sun Y, Meng X, Sun G, Sun X
Cells 2019 Feb 28;8(3) doi: 10.3390/cells8030204. PMID: 30823412Free PMC Article

Prognosis

Role of vitamin D in diabetic retinopathy: Pathophysiological and clinical aspects.
Tecilazich F, Formenti AM, Giustina A
Rev Endocr Metab Disord 2021 Dec;22(4):715-727. doi: 10.1007/s11154-020-09575-4. PMID: 33026598Free PMC Article
Microvascular complications in diabetes: A growing concern for cardiologists.
Avogaro A, Fadini GP
Int J Cardiol 2019 Sep 15;291:29-35. Epub 2019 Feb 25 doi: 10.1016/j.ijcard.2019.02.030. PMID: 30833106
Histopathological changes in major amputations due to diabetic foot - a review.
Gherman D, Dumitrescu CI, Ciocan A, Melincovici CS
Rom J Morphol Embryol 2018;59(3):699-702. PMID: 30534807
The protean role of haptoglobin and haptoglobin genotypes on vascular complications in diabetes mellitus.
Dalan R, Liuh Ling G
Eur J Prev Cardiol 2018 Sep;25(14):1502-1519. Epub 2018 May 25 doi: 10.1177/2047487318776829. PMID: 29799294
Association Between HbA1c Variability and Risk of Microvascular Complications in Adolescents With Type 1 Diabetes.
Virk SA, Donaghue KC, Cho YH, Benitez-Aguirre P, Hing S, Pryke A, Chan A, Craig ME
J Clin Endocrinol Metab 2016 Sep;101(9):3257-63. Epub 2016 May 17 doi: 10.1210/jc.2015-3604. PMID: 27186858

Clinical prediction guides

Incretins and microvascular complications of diabetes: neuropathy, nephropathy, retinopathy and microangiopathy.
Goldney J, Sargeant JA, Davies MJ
Diabetologia 2023 Oct;66(10):1832-1845. Epub 2023 Aug 19 doi: 10.1007/s00125-023-05988-3. PMID: 37597048Free PMC Article
Protection by metformin against severe Covid-19: An in-depth mechanistic analysis.
Wiernsperger N, Al-Salameh A, Cariou B, Lalau JD
Diabetes Metab 2022 Jul;48(4):101359. Epub 2022 May 31 doi: 10.1016/j.diabet.2022.101359. PMID: 35662580Free PMC Article
Role of vitamin D in diabetic retinopathy: Pathophysiological and clinical aspects.
Tecilazich F, Formenti AM, Giustina A
Rev Endocr Metab Disord 2021 Dec;22(4):715-727. doi: 10.1007/s11154-020-09575-4. PMID: 33026598Free PMC Article
Microvascular complications in diabetes: A growing concern for cardiologists.
Avogaro A, Fadini GP
Int J Cardiol 2019 Sep 15;291:29-35. Epub 2019 Feb 25 doi: 10.1016/j.ijcard.2019.02.030. PMID: 30833106
Prevention and treatment of diabetic retinopathy: evidence from clinical trials and perspectives.
Abbate M, Cravedi P, Iliev I, Remuzzi G, Ruggenenti P
Curr Diabetes Rev 2011 May;7(3):190-200. doi: 10.2174/157339911795843168. PMID: 21438851

Recent systematic reviews

Lipid variability and risk of microvascular complications in patients with diabetes: a systematic review and meta-analysis.
Karimi MA, Vaezi A, Ansari A, Archin I, Dadgar K, Rasouli A, Ghannadikhosh P, Alishiri G, Tizro N, Gharei F, Imanparvar S, Salehi S, Mazhari SA, Etemadi MH, Alipour M, Deravi N, Naziri M
BMC Endocr Disord 2024 Jan 2;24(1):4. doi: 10.1186/s12902-023-01526-9. PMID: 38167035Free PMC Article
Dietary Intake and Diabetic Retinopathy: A Systematic Review of the Literature.
Shah J, Cheong ZY, Tan B, Wong D, Liu X, Chua J
Nutrients 2022 Nov 25;14(23) doi: 10.3390/nu14235021. PMID: 36501054Free PMC Article
Influence of antioxidants' gene variants on risk of diabetes mellitus and its complications: a systematic review.
Bitarafan F, Khodaeian M, Tabatabaei-Malazy O, Amoli MM
Minerva Endocrinol 2019 Sep;44(3):310-325. Epub 2017 May 26 doi: 10.23736/S0391-1977.17.02632-3. PMID: 28548478
Diet and risk of diabetic retinopathy: a systematic review.
Dow C, Mancini F, Rajaobelina K, Boutron-Ruault MC, Balkau B, Bonnet F, Fagherazzi G
Eur J Epidemiol 2018 Feb;33(2):141-156. Epub 2017 Dec 4 doi: 10.1007/s10654-017-0338-8. PMID: 29204902
Effects of vitamin E supplementation on glycaemic control in type 2 diabetes: systematic review of randomized controlled trials.
Suksomboon N, Poolsup N, Sinprasert S
J Clin Pharm Ther 2011 Feb;36(1):53-63. doi: 10.1111/j.1365-2710.2009.01154.x. PMID: 21198720

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