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Head and neck neoplasm

MedGen UID:
6728
•Concept ID:
C0018671
•
Neoplastic Process
Synonyms: Head and Neck Neoplasms; Neoplasm of head and neck
SNOMED CT: Neoplasm of head and neck (255055008); Neoplasm of head AND/OR neck (255055008); Tumor of head and neck (255055008)
 
HPO: HP:0012288
Monarch Initiative: MONDO:0005586

Definition

A tumor (abnormal growth of tissue) of the head and neck region with origin in the lip, oral cavity, nasal cavity, paranasal sinuses, pharynx, or larynx. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Head and neck neoplasm

Professional guidelines

PubMed

Challenges in diagnosing head and neck cancer in primary health care.
Nieminen M, Aro K, Mäkitie A, Harlin V, Kainulainen S, Jouhi L, Atula T
Ann Med 2021 Dec;53(1):26-33. Epub 2020 Aug 5 doi: 10.1080/07853890.2020.1802060. PMID: 32746635Free PMC Article
Outcome of multidisciplinary treatment in laryngeal cancer. Retrospective study with 10-years follow-up.
Gurrola-Machuca H, Miranda-Aguirre AP, Villavicencio-Quejeiro M, Nuñez-Guardado G, Juárez-Ramiro A
Cir Cir 2020;88(4):461-466. doi: 10.24875/CIRU.19001540. PMID: 32567606
Head and neck teratoma: from diagnosis to treatment.
Kadlub N, Touma J, Leboulanger N, Garel C, Soupre V, L'Herminé AC, Vazquez MP, Picard A
J Craniomaxillofac Surg 2014 Dec;42(8):1598-603. Epub 2014 May 2 doi: 10.1016/j.jcms.2014.04.028. PMID: 24954765

Recent clinical studies

Etiology

Extra-Nodal Lymphomas of the Head and Neck and Oral Cavity: A Retrospective Study.
Sorrentino A, Ferragina F, Barca I, Arrotta A, Cristofaro MG
Curr Oncol 2022 Sep 29;29(10):7189-7197. doi: 10.3390/curroncol29100566. PMID: 36290843Free PMC Article
Antibiotic prophylaxis in head and neck cancer surgery: Systematic review and Bayesian network meta-analysis.
Iocca O, Copelli C, Ramieri G, Zocchi J, Savo M, Di Maio P
Head Neck 2022 Jan;44(1):254-261. Epub 2021 Nov 6 doi: 10.1002/hed.26908. PMID: 34741354
Head and Neck Cancer Treatments through Chemotherapy to Magnetic Systems: Perspectives and Challenges.
de Lima NRB, de Souza Junior FG, Roullin VG, Pal K, da Silva ND
Curr Radiopharm 2022;15(1):2-20. doi: 10.2174/1874471014999210128183231. PMID: 33511961
Oral cancers: Current status.
D'Cruz AK, Vaish R, Dhar H
Oral Oncol 2018 Dec;87:64-69. Epub 2018 Oct 24 doi: 10.1016/j.oraloncology.2018.10.013. PMID: 30527245
Image guided surgery in the management of head and neck cancer.
Iqbal H, Pan Q
Oral Oncol 2016 Jun;57:32-9. Epub 2016 Apr 25 doi: 10.1016/j.oraloncology.2016.04.007. PMID: 27208842

Diagnosis

Extra-Nodal Lymphomas of the Head and Neck and Oral Cavity: A Retrospective Study.
Sorrentino A, Ferragina F, Barca I, Arrotta A, Cristofaro MG
Curr Oncol 2022 Sep 29;29(10):7189-7197. doi: 10.3390/curroncol29100566. PMID: 36290843Free PMC Article
Head and Neck Cancer Treatments through Chemotherapy to Magnetic Systems: Perspectives and Challenges.
de Lima NRB, de Souza Junior FG, Roullin VG, Pal K, da Silva ND
Curr Radiopharm 2022;15(1):2-20. doi: 10.2174/1874471014999210128183231. PMID: 33511961
Challenges in diagnosing head and neck cancer in primary health care.
Nieminen M, Aro K, Mäkitie A, Harlin V, Kainulainen S, Jouhi L, Atula T
Ann Med 2021 Dec;53(1):26-33. Epub 2020 Aug 5 doi: 10.1080/07853890.2020.1802060. PMID: 32746635Free PMC Article
Oral cancers: Current status.
D'Cruz AK, Vaish R, Dhar H
Oral Oncol 2018 Dec;87:64-69. Epub 2018 Oct 24 doi: 10.1016/j.oraloncology.2018.10.013. PMID: 30527245
Head and neck teratoma: from diagnosis to treatment.
Kadlub N, Touma J, Leboulanger N, Garel C, Soupre V, L'Herminé AC, Vazquez MP, Picard A
J Craniomaxillofac Surg 2014 Dec;42(8):1598-603. Epub 2014 May 2 doi: 10.1016/j.jcms.2014.04.028. PMID: 24954765

Therapy

Antibiotic prophylaxis in head and neck cancer surgery: Systematic review and Bayesian network meta-analysis.
Iocca O, Copelli C, Ramieri G, Zocchi J, Savo M, Di Maio P
Head Neck 2022 Jan;44(1):254-261. Epub 2021 Nov 6 doi: 10.1002/hed.26908. PMID: 34741354
Multimodal Analgesia in Head and Neck Free Flap Reconstruction: A Systematic Review.
Go BC, Go CC, Chorath K, Moreira A, Rajasekaran K
Otolaryngol Head Neck Surg 2022 May;166(5):820-831. Epub 2021 Aug 10 doi: 10.1177/01945998211032910. PMID: 34372726
Head and Neck Cancer Treatments through Chemotherapy to Magnetic Systems: Perspectives and Challenges.
de Lima NRB, de Souza Junior FG, Roullin VG, Pal K, da Silva ND
Curr Radiopharm 2022;15(1):2-20. doi: 10.2174/1874471014999210128183231. PMID: 33511961
Immunonutrition in head and neck cancer: Systematic review and metanalysis of its clinical and nutritional effects.
Lyra MMF, Meira JEC, Guedes GDS, Bueno NB
Clin Nutr ESPEN 2021 Feb;41:30-41. Epub 2021 Jan 11 doi: 10.1016/j.clnesp.2020.12.014. PMID: 33487281
Oral cancers: Current status.
D'Cruz AK, Vaish R, Dhar H
Oral Oncol 2018 Dec;87:64-69. Epub 2018 Oct 24 doi: 10.1016/j.oraloncology.2018.10.013. PMID: 30527245

Prognosis

Head-and-neck dermatofibrosarcoma protuberans: Survival analysis and Clinically relevant immunohistochemical indicators.
Dai Z, He Y, Zhang X, Tian Z, Zhu G, Ren Z, Ye L, Liu Z, Ma C, Cao W, Ji T
Oral Dis 2024 Apr;30(3):1040-1051. Epub 2023 Feb 3 doi: 10.1111/odi.14495. PMID: 36597156
Antibiotic prophylaxis in head and neck cancer surgery: Systematic review and Bayesian network meta-analysis.
Iocca O, Copelli C, Ramieri G, Zocchi J, Savo M, Di Maio P
Head Neck 2022 Jan;44(1):254-261. Epub 2021 Nov 6 doi: 10.1002/hed.26908. PMID: 34741354
Challenges in diagnosing head and neck cancer in primary health care.
Nieminen M, Aro K, Mäkitie A, Harlin V, Kainulainen S, Jouhi L, Atula T
Ann Med 2021 Dec;53(1):26-33. Epub 2020 Aug 5 doi: 10.1080/07853890.2020.1802060. PMID: 32746635Free PMC Article
E-cigarettes and head and neck cancers: A systematic review of the current literature.
Flach S, Maniam P, Manickavasagam J
Clin Otolaryngol 2019 Sep;44(5):749-756. Epub 2019 Jul 23 doi: 10.1111/coa.13384. PMID: 31148389
Image guided surgery in the management of head and neck cancer.
Iqbal H, Pan Q
Oral Oncol 2016 Jun;57:32-9. Epub 2016 Apr 25 doi: 10.1016/j.oraloncology.2016.04.007. PMID: 27208842

Clinical prediction guides

Navigation-assisted maxillofacial reconstruction: accuracy and predictability.
Soh HY, Hu LH, Yu Y, Wang T, Zhang WB, Peng X
Int J Oral Maxillofac Surg 2022 Jul;51(7):874-882. Epub 2021 Nov 30 doi: 10.1016/j.ijom.2021.11.008. PMID: 34862088
Multimodal Analgesia in Head and Neck Free Flap Reconstruction: A Systematic Review.
Go BC, Go CC, Chorath K, Moreira A, Rajasekaran K
Otolaryngol Head Neck Surg 2022 May;166(5):820-831. Epub 2021 Aug 10 doi: 10.1177/01945998211032910. PMID: 34372726
Promoter methylation of galanin receptors as epigenetic biomarkers for head and neck squamous cell carcinomas.
Kanazawa T, Misawa K, Shinmura K, Misawa Y, Kusaka G, Maruta M, Sasaki T, Watanabe Y, Carey TE
Expert Rev Mol Diagn 2019 Feb;19(2):137-148. Epub 2019 Jan 21 doi: 10.1080/14737159.2019.1567334. PMID: 30640567
Head & neck reconstruction: Predictors of readmission.
Graboyes EM, Zenga J, Nussenbaum B
Oral Oncol 2017 Nov;74:159-162. Epub 2017 Jun 28 doi: 10.1016/j.oraloncology.2017.06.022. PMID: 28668299
Extranodal lymphoma of the head and neck: a 67-case series.
Picard A, Cardinne C, Denoux Y, Wagner I, Chabolle F, Bach CA
Eur Ann Otorhinolaryngol Head Neck Dis 2015 Apr;132(2):71-5. Epub 2014 Dec 29 doi: 10.1016/j.anorl.2014.07.005. PMID: 25553969

Recent systematic reviews

Antibiotic prophylaxis in head and neck cancer surgery: Systematic review and Bayesian network meta-analysis.
Iocca O, Copelli C, Ramieri G, Zocchi J, Savo M, Di Maio P
Head Neck 2022 Jan;44(1):254-261. Epub 2021 Nov 6 doi: 10.1002/hed.26908. PMID: 34741354
Multimodal Analgesia in Head and Neck Free Flap Reconstruction: A Systematic Review.
Go BC, Go CC, Chorath K, Moreira A, Rajasekaran K
Otolaryngol Head Neck Surg 2022 May;166(5):820-831. Epub 2021 Aug 10 doi: 10.1177/01945998211032910. PMID: 34372726
Immunonutrition in head and neck cancer: Systematic review and metanalysis of its clinical and nutritional effects.
Lyra MMF, Meira JEC, Guedes GDS, Bueno NB
Clin Nutr ESPEN 2021 Feb;41:30-41. Epub 2021 Jan 11 doi: 10.1016/j.clnesp.2020.12.014. PMID: 33487281
E-cigarettes and head and neck cancers: A systematic review of the current literature.
Flach S, Maniam P, Manickavasagam J
Clin Otolaryngol 2019 Sep;44(5):749-756. Epub 2019 Jul 23 doi: 10.1111/coa.13384. PMID: 31148389
Preoperative radiation and free flap outcomes for head and neck reconstruction: a systematic review and meta-analysis.
Herle P, Shukla L, Morrison WA, Shayan R
ANZ J Surg 2015 Mar;85(3):121-7. Epub 2014 Oct 23 doi: 10.1111/ans.12888. PMID: 25345755

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