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Neoplasms, Ductal, Lobular, and Medullary

MedGen UID:
104937
•Concept ID:
C0206768
•
Neoplastic Process
Synonym: Ductal, Lobular, and Medullary Neoplasms

Definition

Neoplasms, usually carcinoma, located within the center of an organ or within small lobes, and in the case of the breast, intraductally. The emphasis of the name is on the location of the neoplastic tissue rather than on its histological type. Most cancers of this type are located in the breast. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeoplasms, Ductal, Lobular, and Medullary

Professional guidelines

PubMed

Pancreatic Cancer: Pathogenesis, Screening, Diagnosis, and Treatment.
Wood LD, Canto MI, Jaffee EM, Simeone DM
Gastroenterology 2022 Aug;163(2):386-402.e1. Epub 2022 Apr 7 doi: 10.1053/j.gastro.2022.03.056. PMID: 35398344Free PMC Article
Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes.
McGuigan A, Kelly P, Turkington RC, Jones C, Coleman HG, McCain RS
World J Gastroenterol 2018 Nov 21;24(43):4846-4861. doi: 10.3748/wjg.v24.i43.4846. PMID: 30487695Free PMC Article
Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas.
Tanaka M, Fernández-Del Castillo C, Kamisawa T, Jang JY, Levy P, Ohtsuka T, Salvia R, Shimizu Y, Tada M, Wolfgang CL
Pancreatology 2017 Sep-Oct;17(5):738-753. Epub 2017 Jul 13 doi: 10.1016/j.pan.2017.07.007. PMID: 28735806

Recent clinical studies

Etiology

Pathology of invasive breast disease.
Corben AD
Surg Clin North Am 2013 Apr;93(2):363-92. Epub 2013 Feb 13 doi: 10.1016/j.suc.2013.01.003. PMID: 23464691
Prognostic significance of co-expression of RON and MET receptors in node-negative breast cancer patients.
Lee WY, Chen HH, Chow NH, Su WC, Lin PW, Guo HR
Clin Cancer Res 2005 Mar 15;11(6):2222-8. doi: 10.1158/1078-0432.CCR-04-1761. PMID: 15788670
DNA hypomethylation is prevalent even in low-grade breast cancers.
Jackson K, Yu MC, Arakawa K, Fiala E, Youn B, Fiegl H, Müller-Holzner E, Widschwendter M, Ehrlich M
Cancer Biol Ther 2004 Dec;3(12):1225-31. Epub 2004 Dec 9 doi: 10.4161/cbt.3.12.1222. PMID: 15539937
Estrogen receptor codon 594 and HER2 codon 655 polymorphisms and breast cancer risk.
Akisik E, Dalay N
Exp Mol Pathol 2004 Jun;76(3):260-3. doi: 10.1016/j.yexmp.2003.12.005. PMID: 15126109
Contemporary approach to the classification of renal epithelial tumors.
Reuter VE, Presti JC Jr
Semin Oncol 2000 Apr;27(2):124-37. PMID: 10768592

Diagnosis

False-positive and false-negative cases of fine-needle aspiration cytology for palpable breast lesions.
Ishikawa T, Hamaguchi Y, Tanabe M, Momiyama N, Chishima T, Nakatani Y, Nozawa A, Sasaki T, Kitamura H, Shimada H
Breast Cancer 2007;14(4):388-92. doi: 10.2325/jbcs.14.388. PMID: 17986804
Clinical characteristics of different histologic types of breast cancer.
Li CI, Uribe DJ, Daling JR
Br J Cancer 2005 Oct 31;93(9):1046-52. doi: 10.1038/sj.bjc.6602787. PMID: 16175185Free PMC Article
Missed breast carcinoma: pitfalls and pearls.
Majid AS, de Paredes ES, Doherty RD, Sharma NR, Salvador X
Radiographics 2003 Jul-Aug;23(4):881-95. doi: 10.1148/rg.234025083. PMID: 12853663
Breast cancer: diagnosis, treatment and prognosis.
Watson L
Radiol Technol 2001 Sep-Oct;73(1):45-61; quiz 62-4, 67. PMID: 11579771
Primary bilateral mucosa-associated lymphoid tissue lymphoma of the breast with atypical ductal hyperplasia and localized amyloidosis. A case report and review of the literature.
Gupta D, Shidham V, Zemba-Palko V, Keshgegian A
Arch Pathol Lab Med 2000 Aug;124(8):1233-6. doi: 10.5858/2000-124-1233-PBMALT. PMID: 10923092

Therapy

Promoter methylation of RASSF1A modulates the effect of the microtubule-targeting agent docetaxel in breast cancer.
Gil EY, Jo UH, Jeong H, Whang YM, Woo OH, Cho KR, Seo JH, Kim A, Lee ES, Koh I, Kim YH, Park KH
Int J Oncol 2012 Aug;41(2):611-20. Epub 2012 May 10 doi: 10.3892/ijo.2012.1470. PMID: 22581300
Monitoring multiple angiogenesis-related molecules in the blood of cancer patients shows a correlation between VEGF-A and MMP-9 levels before treatment and divergent changes after surgical vs. conservative therapy.
Zaman K, Driscoll R, Hahn D, Werffeli P, Goodman SL, Bauer J, Leyvraz S, Lejeune F, Stupp R, Rüegg C
Int J Cancer 2006 Feb 1;118(3):755-64. doi: 10.1002/ijc.21408. PMID: 16114015
Effects of breast-conserving therapy on lactation after pregnancy.
Moran MS, Colasanto JM, Haffty BG, Wilson LD, Lund MW, Higgins SA
Cancer J 2005 Sep-Oct;11(5):399-403. doi: 10.1097/00130404-200509000-00007. PMID: 16259870
Tissue and serum MUC1 mucin detection in breast cancer patients.
Croce MV, Isla-Larrain MT, Demichelis SO, Gori JR, Price MR, Segal-Eiras A
Breast Cancer Res Treat 2003 Oct;81(3):195-207. doi: 10.1023/A:1026110417294. PMID: 14620915
Histopathologic validation of the sentinel lymph node hypothesis for breast carcinoma.
Turner RR, Ollila DW, Krasne DL, Giuliano AE
Ann Surg 1997 Sep;226(3):271-6; discussion 276-8. doi: 10.1097/00000658-199709000-00006. PMID: 9339933Free PMC Article

Prognosis

Pathology of invasive breast disease.
Corben AD
Surg Clin North Am 2013 Apr;93(2):363-92. Epub 2013 Feb 13 doi: 10.1016/j.suc.2013.01.003. PMID: 23464691
Prognostic significance of co-expression of RON and MET receptors in node-negative breast cancer patients.
Lee WY, Chen HH, Chow NH, Su WC, Lin PW, Guo HR
Clin Cancer Res 2005 Mar 15;11(6):2222-8. doi: 10.1158/1078-0432.CCR-04-1761. PMID: 15788670
DNA hypomethylation is prevalent even in low-grade breast cancers.
Jackson K, Yu MC, Arakawa K, Fiala E, Youn B, Fiegl H, Müller-Holzner E, Widschwendter M, Ehrlich M
Cancer Biol Ther 2004 Dec;3(12):1225-31. Epub 2004 Dec 9 doi: 10.4161/cbt.3.12.1222. PMID: 15539937
Estrogen receptor codon 594 and HER2 codon 655 polymorphisms and breast cancer risk.
Akisik E, Dalay N
Exp Mol Pathol 2004 Jun;76(3):260-3. doi: 10.1016/j.yexmp.2003.12.005. PMID: 15126109
Breast cancer: diagnosis, treatment and prognosis.
Watson L
Radiol Technol 2001 Sep-Oct;73(1):45-61; quiz 62-4, 67. PMID: 11579771

Clinical prediction guides

Pathology of invasive breast disease.
Corben AD
Surg Clin North Am 2013 Apr;93(2):363-92. Epub 2013 Feb 13 doi: 10.1016/j.suc.2013.01.003. PMID: 23464691
Clinical characteristics of different histologic types of breast cancer.
Li CI, Uribe DJ, Daling JR
Br J Cancer 2005 Oct 31;93(9):1046-52. doi: 10.1038/sj.bjc.6602787. PMID: 16175185Free PMC Article
Prognostic significance of co-expression of RON and MET receptors in node-negative breast cancer patients.
Lee WY, Chen HH, Chow NH, Su WC, Lin PW, Guo HR
Clin Cancer Res 2005 Mar 15;11(6):2222-8. doi: 10.1158/1078-0432.CCR-04-1761. PMID: 15788670
Estrogen receptor codon 594 and HER2 codon 655 polymorphisms and breast cancer risk.
Akisik E, Dalay N
Exp Mol Pathol 2004 Jun;76(3):260-3. doi: 10.1016/j.yexmp.2003.12.005. PMID: 15126109
Uptake and washout of 99mTcV-dimercaptosuccinic acid and 99mTc-sestamibi in the assessment of histological type and grade in breast cancer.
Papantoniou V, Christodoulidou J, Papadaki E, Valotassiou V, Souvatzoglou M, Louvrou A, Feida H, Sotiropoulou M, Pampouras G, Michalas S, Zerva C
Nucl Med Commun 2002 May;23(5):461-7. doi: 10.1097/00006231-200205000-00006. PMID: 11973487

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